Publication

Improved methods for binding acma-type protein anchor fusions yo cell-wall material of micro-organisms

Leenhouts, C., Ramasamy, R., Steen, A., Kok, J., Buist, G. & Kuipers, O., 19-Dec-2002, IPC No. A61K 38/ 00 A N, Patent No. WO02101026, Priority date 11-Jun-2001, Priority No. EP20010202239

Research output: PatentProfessional

The invention provides a method for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium, said substance comprising an AcmA cell wall binding domain or homolog or functional derivative thereof, said method comprising treating said cell-wall material with a solution capable of removing a cell-wall component such as a protein, (lipo) teichoic acid or carbohydrate from said cell-wall-material and contacting said substance with said cell-wall material.;The invention provides a method for binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium, said substance comprising an AcmA cell wall binding domain or homolog or functional derivative thereof, said method comprising treating said cell-wall material with a solution capable of removing a cell-wall component such as a protein, (lipo) teichoic acid or carbohydrate from said cell-wall-material and contacting said substance with said cell-wall material.

Original languageEnglish
Patent numberWO02101026
IPCA61K 38/ 00 A N
Priority date11/06/2001
Publication statusPublished - 19-Dec-2002

ID: 27605881