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Implications of Mitochondrial Dysfunction for the Anesthetic and Perioperative Management: A Case Report of Spinal Fusion, Genetic Confusion, and a Patient's Perspective

Aglio, L. S., Lockhart, B. T., Lunshof, J. E. & Nabzdyk, C. S., 1-Mar-2018, In : A & A Practice. 10, 5, p. 103-106 4 p.

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  • Implications of Mitochondrial Dysfunction for the Anesthetic and Perioperative Management

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DOI

We describe a patient's personal struggle with a symptom complex consisting of profound muscle weakness requiring pyridostigmine, and metabolic abnormalities suggestive of mitochondrial disease. This included a profound sensitivity to opioids, which in the past caused severe respiratory depression during a prior hospital admission. Interestingly, the patient herself is a professor of ethics in genomic sciences, and she and her medical team thus far have not been able to formally diagnose her with mitochondrial disease. The patient now presented for a multilevel lumbar spine fusion and her hospital course and perspective on her medical odyssey are described here.

Original languageEnglish
Pages (from-to)103-106
Number of pages4
JournalA & A Practice
Volume10
Issue number5
Publication statusPublished - 1-Mar-2018

    Keywords

  • DISORDERS, MYOPATHY, DEFECTS

ID: 71287003