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Hydrogen sulfide: physiological properties and therapeutic potential in ischaemia

Bos, E. M., van Goor, H., Joles, J. A., Whiteman, M. & Leuvenink, H. G. D., Mar-2015, In : British Journal of Pharmacology. 172, 6, p. 1479-1493 15 p.

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  • Hydrogen sulfide:physiological propertiesand therapeutic potentialin ischaemia

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DOI

Hydrogen sulfide (H2S) has become a molecule of high interest in recent years, and it is now recognized as the third gasotransmitter in addition to nitric oxide and carbon monoxide. In this review, we discuss the recent literature on the physiology of endogenous and exogenous H2S, focusing upon the protective effects of hydrogen sulfide in models of hypoxia and ischaemia.

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Original languageEnglish
Pages (from-to)1479-1493
Number of pages15
JournalBritish Journal of Pharmacology
Volume172
Issue number6
Publication statusPublished - Mar-2015

    Keywords

  • CYSTATHIONINE-BETA-SYNTHASE, NITRIC-OXIDE SYNTHASE, SMOOTH-MUSCLE-CELLS, HEPATIC ISCHEMIA/REPERFUSION INJURY, DONOR KIDNEY-TRANSPLANTATION, ENDOPLASMIC-RETICULUM STRESS, GAMMA-LYASE EXPRESSION, HYPOXIA-INDUCED INJURY, INDUCED HEART-FAILURE, ANIMATION-LIKE STATE

ID: 20602103