How to take a biopsy

Diercks, G. F. H. & Jonkman, M. F., 2016, Autoimmune bullous diseases: Text and Review. Jonkman, M. (ed.). Springer, p. 33-37 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

The skin is an organ that is easy to sample for microscopy. Sections of the skin may reveal the split level of the blister, the type and distribution of invading inflammatory cells, and the presence, class, and distribution pattern of autoantibodies. For this, one needs to take a biopsy from a location with smallest change of sample error and specially fixate and the transport the specimen for the requested microscopic technique. All together, this is the playing ground of the dermatologist. Due to special transport requirements, dermatologists even take conjunctiva biopsies for immunofluorescence (IF) in case of suspicion of an autoimmune bullous disease of the eye.
Original languageEnglish
Title of host publicationAutoimmune bullous diseases
Subtitle of host publicationText and Review
EditorsMarcel Jonkman
Number of pages5
ISBN (Electronic)978-3-319-23754-1
ISBN (Print)978-3-319-23753-4
Publication statusPublished - 2016


  • Histopathology, Immunofluorescence, Biopsy

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