Publication

How does ageing affect the impact of medically unexplained symptoms and medically explained symptoms on health-related quality of life?

Hilderink, P. H., Collard, R., Rosmalen, J. G. M. & Oude Voshaar, R., Jul-2015, In : International Journal of Geriatric Psychiatry. 30, 7, p. 737-743 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Hilderink, P. H., Collard, R., Rosmalen, J. G. M., & Oude Voshaar, R. (2015). How does ageing affect the impact of medically unexplained symptoms and medically explained symptoms on health-related quality of life? International Journal of Geriatric Psychiatry, 30(7), 737-743. https://doi.org/10.1002/gps.4219

Author

Hilderink, Peter H. ; Collard, Rose ; Rosmalen, Judith G. M. ; Oude Voshaar, Richard. / How does ageing affect the impact of medically unexplained symptoms and medically explained symptoms on health-related quality of life?. In: International Journal of Geriatric Psychiatry. 2015 ; Vol. 30, No. 7. pp. 737-743.

Harvard

Hilderink, PH, Collard, R, Rosmalen, JGM & Oude Voshaar, R 2015, 'How does ageing affect the impact of medically unexplained symptoms and medically explained symptoms on health-related quality of life?', International Journal of Geriatric Psychiatry, vol. 30, no. 7, pp. 737-743. https://doi.org/10.1002/gps.4219

Standard

How does ageing affect the impact of medically unexplained symptoms and medically explained symptoms on health-related quality of life? / Hilderink, Peter H.; Collard, Rose; Rosmalen, Judith G. M.; Oude Voshaar, Richard.

In: International Journal of Geriatric Psychiatry, Vol. 30, No. 7, 07.2015, p. 737-743.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Hilderink PH, Collard R, Rosmalen JGM, Oude Voshaar R. How does ageing affect the impact of medically unexplained symptoms and medically explained symptoms on health-related quality of life? International Journal of Geriatric Psychiatry. 2015 Jul;30(7):737-743. https://doi.org/10.1002/gps.4219


BibTeX

@article{32757da574024b1f93eba72c1fd68c77,
title = "How does ageing affect the impact of medically unexplained symptoms and medically explained symptoms on health-related quality of life?",
abstract = "BACKGROUND: Physical symptoms significantly impair health-related quality of life (HRQoL), but age effects and differential effects of medically unexplained symptoms (MUS) and medically explained symptoms (MES) have hardly been examined. Our objective was to determine the effect of age on the impact of MUS and MES on HRQoL.METHODS: In a population-based cohort (n = 946, aged 28-75 years), MUS and MES were measured using the Composite International Diagnostic Interview and HRQoL using the EuroQol-5 dimensions (EQ-5D). Using multiple linear regression, we regressed MUS, MES and their interaction with age on HRQoL, adjusted for socio-demographic variables and the presence of depressive and anxiety disorders. In case of significant interaction terms, age-stratified results will be presented.RESULTS: In the whole study population, the association between MUS and HRQoL was stronger (β = -0.35; p < 0.001) than between MES and HRQoL (β = -0.26; p < 0.001). Adjusted for depressive and anxiety disorders, differences between these associations decline (MUS: β = -0.28, p < 0.001; MES: β = -0.25, p < 0.001). Age significantly interacted with number of MUS in explaining variance in HRQoL but not with the number of MES. The impact of MUS on HRQoL is much larger in people aged below 65 years (β = -0.39, p < 0.001) versus those aged 65 years and over (β = -0.21, p = 0.002). In the older group, the association between MUS and HRQoL lost significance when adjusted for depressive and anxiety disorders (β = -0.12 p = 0.062).CONCLUSION: Our results show that age affects the association between MUS and HRQoL, which suggest that older persons cope better with MUS than younger persons. Copyright {\textcopyright} 2014 John Wiley & Sons, Ltd.",
keywords = "medically unexplained symptoms, quality of life, aged, medically explained, symptoms, INTERNATIONAL DIAGNOSTIC INTERVIEW, OLDER-PEOPLE, CHRONIC PAIN, FOLLOW-UP, SOMATOFORM DISORDERS, AGE, SOMATIZATION, POPULATION, DEPRESSION, COMPLAINTS",
author = "Hilderink, {Peter H.} and Rose Collard and Rosmalen, {Judith G. M.} and {Oude Voshaar}, Richard",
note = "Copyright {\textcopyright} 2014 John Wiley & Sons, Ltd.",
year = "2015",
month = jul,
doi = "10.1002/gps.4219",
language = "English",
volume = "30",
pages = "737--743",
journal = "International Journal of Geriatric Psychiatry",
issn = "0885-6230",
publisher = "Wiley",
number = "7",

}

RIS

TY - JOUR

T1 - How does ageing affect the impact of medically unexplained symptoms and medically explained symptoms on health-related quality of life?

AU - Hilderink, Peter H.

AU - Collard, Rose

AU - Rosmalen, Judith G. M.

AU - Oude Voshaar, Richard

N1 - Copyright © 2014 John Wiley & Sons, Ltd.

PY - 2015/7

Y1 - 2015/7

N2 - BACKGROUND: Physical symptoms significantly impair health-related quality of life (HRQoL), but age effects and differential effects of medically unexplained symptoms (MUS) and medically explained symptoms (MES) have hardly been examined. Our objective was to determine the effect of age on the impact of MUS and MES on HRQoL.METHODS: In a population-based cohort (n = 946, aged 28-75 years), MUS and MES were measured using the Composite International Diagnostic Interview and HRQoL using the EuroQol-5 dimensions (EQ-5D). Using multiple linear regression, we regressed MUS, MES and their interaction with age on HRQoL, adjusted for socio-demographic variables and the presence of depressive and anxiety disorders. In case of significant interaction terms, age-stratified results will be presented.RESULTS: In the whole study population, the association between MUS and HRQoL was stronger (β = -0.35; p < 0.001) than between MES and HRQoL (β = -0.26; p < 0.001). Adjusted for depressive and anxiety disorders, differences between these associations decline (MUS: β = -0.28, p < 0.001; MES: β = -0.25, p < 0.001). Age significantly interacted with number of MUS in explaining variance in HRQoL but not with the number of MES. The impact of MUS on HRQoL is much larger in people aged below 65 years (β = -0.39, p < 0.001) versus those aged 65 years and over (β = -0.21, p = 0.002). In the older group, the association between MUS and HRQoL lost significance when adjusted for depressive and anxiety disorders (β = -0.12 p = 0.062).CONCLUSION: Our results show that age affects the association between MUS and HRQoL, which suggest that older persons cope better with MUS than younger persons. Copyright © 2014 John Wiley & Sons, Ltd.

AB - BACKGROUND: Physical symptoms significantly impair health-related quality of life (HRQoL), but age effects and differential effects of medically unexplained symptoms (MUS) and medically explained symptoms (MES) have hardly been examined. Our objective was to determine the effect of age on the impact of MUS and MES on HRQoL.METHODS: In a population-based cohort (n = 946, aged 28-75 years), MUS and MES were measured using the Composite International Diagnostic Interview and HRQoL using the EuroQol-5 dimensions (EQ-5D). Using multiple linear regression, we regressed MUS, MES and their interaction with age on HRQoL, adjusted for socio-demographic variables and the presence of depressive and anxiety disorders. In case of significant interaction terms, age-stratified results will be presented.RESULTS: In the whole study population, the association between MUS and HRQoL was stronger (β = -0.35; p < 0.001) than between MES and HRQoL (β = -0.26; p < 0.001). Adjusted for depressive and anxiety disorders, differences between these associations decline (MUS: β = -0.28, p < 0.001; MES: β = -0.25, p < 0.001). Age significantly interacted with number of MUS in explaining variance in HRQoL but not with the number of MES. The impact of MUS on HRQoL is much larger in people aged below 65 years (β = -0.39, p < 0.001) versus those aged 65 years and over (β = -0.21, p = 0.002). In the older group, the association between MUS and HRQoL lost significance when adjusted for depressive and anxiety disorders (β = -0.12 p = 0.062).CONCLUSION: Our results show that age affects the association between MUS and HRQoL, which suggest that older persons cope better with MUS than younger persons. Copyright © 2014 John Wiley & Sons, Ltd.

KW - medically unexplained symptoms

KW - quality of life

KW - aged

KW - medically explained

KW - symptoms

KW - INTERNATIONAL DIAGNOSTIC INTERVIEW

KW - OLDER-PEOPLE

KW - CHRONIC PAIN

KW - FOLLOW-UP

KW - SOMATOFORM DISORDERS

KW - AGE

KW - SOMATIZATION

KW - POPULATION

KW - DEPRESSION

KW - COMPLAINTS

U2 - 10.1002/gps.4219

DO - 10.1002/gps.4219

M3 - Article

C2 - 25349149

VL - 30

SP - 737

EP - 743

JO - International Journal of Geriatric Psychiatry

JF - International Journal of Geriatric Psychiatry

SN - 0885-6230

IS - 7

ER -

ID: 15172434