Publication

Het effect van de CBG-waarschuwing op de trend in SSRI-gebruik in Nederland van 1998 tot 2010

Bijlsma, M. J., Oortgiesen, B. E., Beernink, R. H. J., Bos, J., Wilffert, B. & Hak, E., 21-Feb-2014, In : Pharmaceutisch Weekblad Wetenschappelijk Platform. 149, 8, p. 32-36 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Bijlsma, M. J., Oortgiesen, B. E., Beernink, R. H. J., Bos, J., Wilffert, B., & Hak, E. (2014). Het effect van de CBG-waarschuwing op de trend in SSRI-gebruik in Nederland van 1998 tot 2010. Pharmaceutisch Weekblad Wetenschappelijk Platform, 149(8), 32-36.

Author

Bijlsma, Maarten J. ; Oortgiesen, Berdien E. ; Beernink, Rik H. J. ; Bos, Jens ; Wilffert, Bob ; Hak, Eelko. / Het effect van de CBG-waarschuwing op de trend in SSRI-gebruik in Nederland van 1998 tot 2010. In: Pharmaceutisch Weekblad Wetenschappelijk Platform. 2014 ; Vol. 149, No. 8. pp. 32-36.

Harvard

Bijlsma, MJ, Oortgiesen, BE, Beernink, RHJ, Bos, J, Wilffert, B & Hak, E 2014, 'Het effect van de CBG-waarschuwing op de trend in SSRI-gebruik in Nederland van 1998 tot 2010' Pharmaceutisch Weekblad Wetenschappelijk Platform, vol. 149, no. 8, pp. 32-36.

Standard

Het effect van de CBG-waarschuwing op de trend in SSRI-gebruik in Nederland van 1998 tot 2010. / Bijlsma, Maarten J.; Oortgiesen, Berdien E.; Beernink, Rik H. J.; Bos, Jens; Wilffert, Bob; Hak, Eelko.

In: Pharmaceutisch Weekblad Wetenschappelijk Platform, Vol. 149, No. 8, 21.02.2014, p. 32-36.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Bijlsma MJ, Oortgiesen BE, Beernink RHJ, Bos J, Wilffert B, Hak E. Het effect van de CBG-waarschuwing op de trend in SSRI-gebruik in Nederland van 1998 tot 2010. Pharmaceutisch Weekblad Wetenschappelijk Platform. 2014 Feb 21;149(8):32-36.


BibTeX

@article{a0a0710a17aa475380834f4ee6f95db4,
title = "Het effect van de CBG-waarschuwing op de trend in SSRI-gebruik in Nederland van 1998 tot 2010",
abstract = "OBJECTIVE: To determine the effect of the warning by the Dutch Medicines Evaluation Board (CBG) in 2004 concerning SSRI use by children on the trend of SSRI utilization in the Dutch population in the period 1998-2010. DESIGN: Interrupted time series analysis. METHODS: Yearly prevalence of SSRI utilization (excluding fluoxetine) was calculated for the age categories 12-18, 19-24, 25-49, 50-64 and 65-84 years. Regression was used to determine whether the trend in SSRI utilization after 2004 changed significantly from the trend before 2004. RESULTS: Prevalence in SSRI utilization in age groups 12-18, 19-24 and 25-49 years increased in the period 1998 to 2004 and started to decline after 2004 (P <0.001) until 2010. Prevalence in age categories 50-64 and 64-84 years increased in the period 1998 to 2004 and the increase in prevalence afterwards is not significantly different from 0. Prevalence of fluoxetine utilization declined throughout the study period. CONCLUSION: The CBG warning appears to strongly affect the trends in the utilization of SSRIs (excluding fluoxetine) in the Netherlands. It is noteworthy that the trends in SSRI utilization in age categories above 24 years, at which the warning was not aimed, significantly changed after 2004.",
keywords = "serotonin uptake inhibitor, adolescent, adult, aged, article, child, child care, drug utilization, human, middle aged, Netherlands, prevalence, school child, very elderly, young adult",
author = "Bijlsma, {Maarten J.} and Oortgiesen, {Berdien E.} and Beernink, {Rik H. J.} and Jens Bos and Bob Wilffert and Eelko Hak",
year = "2014",
month = "2",
day = "21",
language = "Dutch",
volume = "149",
pages = "32--36",
journal = "Pharmaceutisch Weekblad",
issn = "0031-6911",
number = "8",

}

RIS

TY - JOUR

T1 - Het effect van de CBG-waarschuwing op de trend in SSRI-gebruik in Nederland van 1998 tot 2010

AU - Bijlsma, Maarten J.

AU - Oortgiesen, Berdien E.

AU - Beernink, Rik H. J.

AU - Bos, Jens

AU - Wilffert, Bob

AU - Hak, Eelko

PY - 2014/2/21

Y1 - 2014/2/21

N2 - OBJECTIVE: To determine the effect of the warning by the Dutch Medicines Evaluation Board (CBG) in 2004 concerning SSRI use by children on the trend of SSRI utilization in the Dutch population in the period 1998-2010. DESIGN: Interrupted time series analysis. METHODS: Yearly prevalence of SSRI utilization (excluding fluoxetine) was calculated for the age categories 12-18, 19-24, 25-49, 50-64 and 65-84 years. Regression was used to determine whether the trend in SSRI utilization after 2004 changed significantly from the trend before 2004. RESULTS: Prevalence in SSRI utilization in age groups 12-18, 19-24 and 25-49 years increased in the period 1998 to 2004 and started to decline after 2004 (P <0.001) until 2010. Prevalence in age categories 50-64 and 64-84 years increased in the period 1998 to 2004 and the increase in prevalence afterwards is not significantly different from 0. Prevalence of fluoxetine utilization declined throughout the study period. CONCLUSION: The CBG warning appears to strongly affect the trends in the utilization of SSRIs (excluding fluoxetine) in the Netherlands. It is noteworthy that the trends in SSRI utilization in age categories above 24 years, at which the warning was not aimed, significantly changed after 2004.

AB - OBJECTIVE: To determine the effect of the warning by the Dutch Medicines Evaluation Board (CBG) in 2004 concerning SSRI use by children on the trend of SSRI utilization in the Dutch population in the period 1998-2010. DESIGN: Interrupted time series analysis. METHODS: Yearly prevalence of SSRI utilization (excluding fluoxetine) was calculated for the age categories 12-18, 19-24, 25-49, 50-64 and 65-84 years. Regression was used to determine whether the trend in SSRI utilization after 2004 changed significantly from the trend before 2004. RESULTS: Prevalence in SSRI utilization in age groups 12-18, 19-24 and 25-49 years increased in the period 1998 to 2004 and started to decline after 2004 (P <0.001) until 2010. Prevalence in age categories 50-64 and 64-84 years increased in the period 1998 to 2004 and the increase in prevalence afterwards is not significantly different from 0. Prevalence of fluoxetine utilization declined throughout the study period. CONCLUSION: The CBG warning appears to strongly affect the trends in the utilization of SSRIs (excluding fluoxetine) in the Netherlands. It is noteworthy that the trends in SSRI utilization in age categories above 24 years, at which the warning was not aimed, significantly changed after 2004.

KW - serotonin uptake inhibitor

KW - adolescent

KW - adult

KW - aged

KW - article

KW - child

KW - child care

KW - drug utilization

KW - human

KW - middle aged

KW - Netherlands

KW - prevalence

KW - school child

KW - very elderly

KW - young adult

M3 - Article

VL - 149

SP - 32

EP - 36

JO - Pharmaceutisch Weekblad

JF - Pharmaceutisch Weekblad

SN - 0031-6911

IS - 8

ER -

ID: 14124685