Het denosumab-dilemma: Na 5 jaar stoppen of doorgaan bij patiënten met osteoporose?

Wolffenbuttel, B. H. R., Abma, E. M. & Appelman-Dijkstra, N. M., 18-May-2018, In : Nederlands Tijdschrift voor Geneeskunde. 162, 21, 3 p., D2831.

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  • Het denosumab-dilemma

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Denosumab is an effective treatment for osteoporosis. However, an increasing number of patients are developing so-called rebound vertebral fractures, because of a considerable increase of bone resorption after cessation of denosumab therapy. The prevalence of these new vertebral fractures is still unknown. In patients with high risk of new fractures, it is recommended to consider continuing denosumab treatment, or to switch to another antiresorptive medication such as bisphosphonates.

Original languageDutch
Article numberD2831
Number of pages3
JournalNederlands Tijdschrift voor Geneeskunde
Issue number21
Publication statusPublished - 18-May-2018

ID: 77222117