Publication

Health-Related Quality of Life in Older Persons with Medically Unexplained Symptoms

Hanssen, D. J. C., Lucassen, P. L. B. J., Hilderink, P. H., Naarding, P. & Oude Voshaar, R., Nov-2016, In : American Journal of Geriatric Psychiatry. 24, 11, p. 1117-1127 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Hanssen, D. J. C., Lucassen, P. L. B. J., Hilderink, P. H., Naarding, P., & Oude Voshaar, R. (2016). Health-Related Quality of Life in Older Persons with Medically Unexplained Symptoms. American Journal of Geriatric Psychiatry, 24(11), 1117-1127. https://doi.org/10.1016/j.jagp.2016.07.013

Author

Hanssen, Denise J. C. ; Lucassen, Peter L. B. J. ; Hilderink, Peter H. ; Naarding, Paul ; Oude Voshaar, Richard. / Health-Related Quality of Life in Older Persons with Medically Unexplained Symptoms. In: American Journal of Geriatric Psychiatry. 2016 ; Vol. 24, No. 11. pp. 1117-1127.

Harvard

Hanssen, DJC, Lucassen, PLBJ, Hilderink, PH, Naarding, P & Oude Voshaar, R 2016, 'Health-Related Quality of Life in Older Persons with Medically Unexplained Symptoms', American Journal of Geriatric Psychiatry, vol. 24, no. 11, pp. 1117-1127. https://doi.org/10.1016/j.jagp.2016.07.013

Standard

Health-Related Quality of Life in Older Persons with Medically Unexplained Symptoms. / Hanssen, Denise J. C.; Lucassen, Peter L. B. J.; Hilderink, Peter H.; Naarding, Paul; Oude Voshaar, Richard.

In: American Journal of Geriatric Psychiatry, Vol. 24, No. 11, 11.2016, p. 1117-1127.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Hanssen DJC, Lucassen PLBJ, Hilderink PH, Naarding P, Oude Voshaar R. Health-Related Quality of Life in Older Persons with Medically Unexplained Symptoms. American Journal of Geriatric Psychiatry. 2016 Nov;24(11):1117-1127. https://doi.org/10.1016/j.jagp.2016.07.013


BibTeX

@article{8fc2bbac894e4be6895ada58e28b9631,
title = "Health-Related Quality of Life in Older Persons with Medically Unexplained Symptoms",
abstract = "Objective: Research on health-related quality of life (HRQoL) in older persons with medically unexplained symptoms (MUS) is scarce, and, in contrast with younger patients, interactions with chronic somatic diseases are more complex. Design: In the current study we compared HRQoL between older persons with MUS and older persons with medically explained symptoms (MES). Our study sample consisted of 118 older MUS-patients and 154 older MES-patients. Setting/Measurements: The diagnosis of MUS was ascertained by the general practitioner and confirmed by a geriatrician within a multidisciplinary diagnostic assessment. Additional characteristics, including the HRQoL (Short Form-36), were assessed during a home visit. MES-patients received two home visits to assess all measures. Multiple linear regression analyses, adjusted for age, sex, education, cognitive functioning, and psychiatric diagnoses, were performed to assess the relationship between group (MUS/MES) and HRQoL. Analyses were repeated with additional adjustments for somatization and hypochondriacal cognitions. Results: Older patients with MUS had a significantly lower level of HRQoL compared with older patients with MES. Even after adjustments, the presence of MUS was still associated with both a lower physical and mental HRQoL. These associations disappeared, however, after additional adjustments for somatization and hypochondriacal cognitions. Within the subgroup of MUS-patients, higher levels of hypochondriac anxiety and of somatization were significantly associated with both lower physical and mental HRQoL. Conclusions: Associations between HRQoL and late-life MUS disappear when corrected for somatization and hypochondriacal cognitions, which is in line with the DSM-5 classification of somatic symptom disorder. Appropriate psychological treatment seems needed to improve HRQoL in older MUS-patients.",
keywords = "aged, medically unexplained symptoms, quality of life, somatization, IRRITABLE-BOWEL-SYNDROME, FUNCTIONAL SOMATIC SYNDROMES, PHYSICAL SYMPTOMS, CONCEPTUAL-MODEL, GENERAL-PRACTICE, CARE, SOMATIZATION, DISORDERS, POPULATION, IMPACT",
author = "Hanssen, {Denise J. C.} and Lucassen, {Peter L. B. J.} and Hilderink, {Peter H.} and Paul Naarding and {Oude Voshaar}, Richard",
year = "2016",
month = nov,
doi = "10.1016/j.jagp.2016.07.013",
language = "English",
volume = "24",
pages = "1117--1127",
journal = "American Journal of Geriatric Psychiatry",
issn = "1064-7481",
publisher = "ELSEVIER SCIENCE INC",
number = "11",

}

RIS

TY - JOUR

T1 - Health-Related Quality of Life in Older Persons with Medically Unexplained Symptoms

AU - Hanssen, Denise J. C.

AU - Lucassen, Peter L. B. J.

AU - Hilderink, Peter H.

AU - Naarding, Paul

AU - Oude Voshaar, Richard

PY - 2016/11

Y1 - 2016/11

N2 - Objective: Research on health-related quality of life (HRQoL) in older persons with medically unexplained symptoms (MUS) is scarce, and, in contrast with younger patients, interactions with chronic somatic diseases are more complex. Design: In the current study we compared HRQoL between older persons with MUS and older persons with medically explained symptoms (MES). Our study sample consisted of 118 older MUS-patients and 154 older MES-patients. Setting/Measurements: The diagnosis of MUS was ascertained by the general practitioner and confirmed by a geriatrician within a multidisciplinary diagnostic assessment. Additional characteristics, including the HRQoL (Short Form-36), were assessed during a home visit. MES-patients received two home visits to assess all measures. Multiple linear regression analyses, adjusted for age, sex, education, cognitive functioning, and psychiatric diagnoses, were performed to assess the relationship between group (MUS/MES) and HRQoL. Analyses were repeated with additional adjustments for somatization and hypochondriacal cognitions. Results: Older patients with MUS had a significantly lower level of HRQoL compared with older patients with MES. Even after adjustments, the presence of MUS was still associated with both a lower physical and mental HRQoL. These associations disappeared, however, after additional adjustments for somatization and hypochondriacal cognitions. Within the subgroup of MUS-patients, higher levels of hypochondriac anxiety and of somatization were significantly associated with both lower physical and mental HRQoL. Conclusions: Associations between HRQoL and late-life MUS disappear when corrected for somatization and hypochondriacal cognitions, which is in line with the DSM-5 classification of somatic symptom disorder. Appropriate psychological treatment seems needed to improve HRQoL in older MUS-patients.

AB - Objective: Research on health-related quality of life (HRQoL) in older persons with medically unexplained symptoms (MUS) is scarce, and, in contrast with younger patients, interactions with chronic somatic diseases are more complex. Design: In the current study we compared HRQoL between older persons with MUS and older persons with medically explained symptoms (MES). Our study sample consisted of 118 older MUS-patients and 154 older MES-patients. Setting/Measurements: The diagnosis of MUS was ascertained by the general practitioner and confirmed by a geriatrician within a multidisciplinary diagnostic assessment. Additional characteristics, including the HRQoL (Short Form-36), were assessed during a home visit. MES-patients received two home visits to assess all measures. Multiple linear regression analyses, adjusted for age, sex, education, cognitive functioning, and psychiatric diagnoses, were performed to assess the relationship between group (MUS/MES) and HRQoL. Analyses were repeated with additional adjustments for somatization and hypochondriacal cognitions. Results: Older patients with MUS had a significantly lower level of HRQoL compared with older patients with MES. Even after adjustments, the presence of MUS was still associated with both a lower physical and mental HRQoL. These associations disappeared, however, after additional adjustments for somatization and hypochondriacal cognitions. Within the subgroup of MUS-patients, higher levels of hypochondriac anxiety and of somatization were significantly associated with both lower physical and mental HRQoL. Conclusions: Associations between HRQoL and late-life MUS disappear when corrected for somatization and hypochondriacal cognitions, which is in line with the DSM-5 classification of somatic symptom disorder. Appropriate psychological treatment seems needed to improve HRQoL in older MUS-patients.

KW - aged

KW - medically unexplained symptoms

KW - quality of life

KW - somatization

KW - IRRITABLE-BOWEL-SYNDROME

KW - FUNCTIONAL SOMATIC SYNDROMES

KW - PHYSICAL SYMPTOMS

KW - CONCEPTUAL-MODEL

KW - GENERAL-PRACTICE

KW - CARE

KW - SOMATIZATION

KW - DISORDERS

KW - POPULATION

KW - IMPACT

U2 - 10.1016/j.jagp.2016.07.013

DO - 10.1016/j.jagp.2016.07.013

M3 - Article

C2 - 27618643

VL - 24

SP - 1117

EP - 1127

JO - American Journal of Geriatric Psychiatry

JF - American Journal of Geriatric Psychiatry

SN - 1064-7481

IS - 11

ER -

ID: 37474301