Publication

Hansenula polymorpha Tup1p is important for peroxisome degradation

Leão-Helder, A. N., Krikken, A. M., Lunenborg, M. G. J., Kiel, J. A. K. W., Veenhuis, M. & van der Klei, I. J., 2004, In : Fems Yeast Research. 4, 8, p. 789 - 794 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Leão-Helder, A. N., Krikken, A. M., Lunenborg, M. G. J., Kiel, J. A. K. W., Veenhuis, M., & van der Klei, I. J. (2004). Hansenula polymorpha Tup1p is important for peroxisome degradation. Fems Yeast Research, 4(8), 789 - 794. https://doi.org/10.1016/j.femsyr.2004.04.006

Author

Leão-Helder, Adriana N ; Krikken, Arjen M ; Lunenborg, Marcel G J ; Kiel, Jan A K W ; Veenhuis, Marten ; van der Klei, Ida J. / Hansenula polymorpha Tup1p is important for peroxisome degradation. In: Fems Yeast Research. 2004 ; Vol. 4, No. 8. pp. 789 - 794.

Harvard

Leão-Helder, AN, Krikken, AM, Lunenborg, MGJ, Kiel, JAKW, Veenhuis, M & van der Klei, IJ 2004, 'Hansenula polymorpha Tup1p is important for peroxisome degradation', Fems Yeast Research, vol. 4, no. 8, pp. 789 - 794. https://doi.org/10.1016/j.femsyr.2004.04.006

Standard

Hansenula polymorpha Tup1p is important for peroxisome degradation. / Leão-Helder, Adriana N; Krikken, Arjen M; Lunenborg, Marcel G J; Kiel, Jan A K W; Veenhuis, Marten; van der Klei, Ida J.

In: Fems Yeast Research, Vol. 4, No. 8, 2004, p. 789 - 794.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Leão-Helder AN, Krikken AM, Lunenborg MGJ, Kiel JAKW, Veenhuis M, van der Klei IJ. Hansenula polymorpha Tup1p is important for peroxisome degradation. Fems Yeast Research. 2004;4(8):789 - 794. https://doi.org/10.1016/j.femsyr.2004.04.006


BibTeX

@article{64d65fc7eabe45a19ff160e837740dc6,
title = "Hansenula polymorpha Tup1p is important for peroxisome degradation",
abstract = "In the yeast Hansenula polymorpha peroxisomes are selectively degraded upon a shift of cells from methanol to glucose-containing media. We identified the H. polymorpha TUP1 gene by functional complementation of the peroxisome degradation deficient mutant pdd2-4. Tup1 proteins function in transcriptional repression of specific sets of genes involved in various cellular processes. Our combined data indicate that H. polymorpha TUP1 is involved in regulation of the switch between peroxisome biogenesis and selective degradation. The initial DNA fragment that complemented H. polymorpha pdd2-4 contained a second gene, encoding H. polymorpha Vps4p. Deletion of the VPS4 gene did not affect selective peroxisome degradation.",
keywords = "Amino Acid Sequence, Gene Expression Regulation, Fungal, Genes, Fungal, Genetic Complementation Test, Molecular Sequence Data, Peroxisomes, Pichia",
author = "Le{\~a}o-Helder, {Adriana N} and Krikken, {Arjen M} and Lunenborg, {Marcel G J} and Kiel, {Jan A K W} and Marten Veenhuis and {van der Klei}, {Ida J}",
note = "Relation: https://www.rug.nl/gbb/ date_submitted:2007 Rights: University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute",
year = "2004",
doi = "10.1016/j.femsyr.2004.04.006",
language = "English",
volume = "4",
pages = "789 -- 794",
journal = "Fems Yeast Research",
issn = "1567-1356",
number = "8",

}

RIS

TY - JOUR

T1 - Hansenula polymorpha Tup1p is important for peroxisome degradation

AU - Leão-Helder, Adriana N

AU - Krikken, Arjen M

AU - Lunenborg, Marcel G J

AU - Kiel, Jan A K W

AU - Veenhuis, Marten

AU - van der Klei, Ida J

N1 - Relation: https://www.rug.nl/gbb/ date_submitted:2007 Rights: University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute

PY - 2004

Y1 - 2004

N2 - In the yeast Hansenula polymorpha peroxisomes are selectively degraded upon a shift of cells from methanol to glucose-containing media. We identified the H. polymorpha TUP1 gene by functional complementation of the peroxisome degradation deficient mutant pdd2-4. Tup1 proteins function in transcriptional repression of specific sets of genes involved in various cellular processes. Our combined data indicate that H. polymorpha TUP1 is involved in regulation of the switch between peroxisome biogenesis and selective degradation. The initial DNA fragment that complemented H. polymorpha pdd2-4 contained a second gene, encoding H. polymorpha Vps4p. Deletion of the VPS4 gene did not affect selective peroxisome degradation.

AB - In the yeast Hansenula polymorpha peroxisomes are selectively degraded upon a shift of cells from methanol to glucose-containing media. We identified the H. polymorpha TUP1 gene by functional complementation of the peroxisome degradation deficient mutant pdd2-4. Tup1 proteins function in transcriptional repression of specific sets of genes involved in various cellular processes. Our combined data indicate that H. polymorpha TUP1 is involved in regulation of the switch between peroxisome biogenesis and selective degradation. The initial DNA fragment that complemented H. polymorpha pdd2-4 contained a second gene, encoding H. polymorpha Vps4p. Deletion of the VPS4 gene did not affect selective peroxisome degradation.

KW - Amino Acid Sequence

KW - Gene Expression Regulation, Fungal

KW - Genes, Fungal

KW - Genetic Complementation Test

KW - Molecular Sequence Data

KW - Peroxisomes

KW - Pichia

U2 - 10.1016/j.femsyr.2004.04.006

DO - 10.1016/j.femsyr.2004.04.006

M3 - Article

C2 - 15450185

VL - 4

SP - 789

EP - 794

JO - Fems Yeast Research

JF - Fems Yeast Research

SN - 1567-1356

IS - 8

ER -

ID: 2960031