Gut Microbiota in Obesity and Undernutrition

de Clercq, N. C., Groen, A. K., Romijn, J. A. & Nieuwdorp, M., Nov-2016, In : Advances in nutrition. 7, 6, p. 1080-1089 10 p.

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  • Gut Microbiota in Obesity and Undernutrition

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Malnutrition is the result of an inadequate balance between energy intake and energy expenditure that ultimately leads to either obesity or undernutrition. Several factors are associated with the onset and preservation of malnutrition. One of these factors is the gut microbiota, which has been recognized as an important pathophysiologic factor in the development and sustainment of malnutrition. However, to our knowledge, the extent to which the microbiota influences malnutrition has yet to be elucidated. In this review, we summarize the mechanisms via which the gut microbiota may influence energy homeostasis in relation to malnutrition. In addition, we discuss potential therapeutic modalities to ameliorate obesity or undernutrition.

Original languageEnglish
Pages (from-to)1080-1089
Number of pages10
JournalAdvances in nutrition
Issue number6
Publication statusPublished - Nov-2016
Event5th Annual Advances and Controversies in Clinical Nutrition Confernce - Long Beach, Canada
Duration: 4-Dec-20156-Dec-2015


5th Annual Advances and Controversies in Clinical Nutrition Confernce


Long Beach, Canada

Event: Conference


  • malnutrition, obesity, undernutrition, gut microbiota, energy homeostasis, appetite, gut, brain axis, probiotics, prebiotics, fecal transplantation, CHAIN FATTY-ACIDS, GLUCAGON-LIKE PEPTIDE-1, DIET-INDUCED OBESITY, RANDOMIZED CONTROLLED-TRIAL, NERVOUS-SYSTEM CONTROL, BODY-WEIGHT, ADIPOSE-TISSUE, FOOD-INTAKE, INTESTINAL MICROBIOTA, ENERGY-EXPENDITURE

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