Glycoconjugates via Phosphorus YlidesGhonchepour, E., Neochoritis, C. G., Kurpiewska, K., Kalinowska-Tluscik, J., Islami, M. R. & Domling, A., 16-Jun-2019, In : European Journal of Organic Chemistry. 2019, 22, p. 3632-3635 4 p.
Research output: Contribution to journal › Article › Academic › peer-review
A facile, high yielding access to rare chimeric compounds combining phosphorus ylides with complex glycosyl formamides is described. We determined X-ray structures gaining structural insight into this compounds class. In addition, data mining of similar compounds deposited within the Cambridge Structural Database was performed. These derivatives could be used either as synthetic intermediates via the ylide functionalization and glyco chemical biology synthons or improving the pharmacokinetic properties of a potential bioactive molecule, exploiting the glycosyl moiety.
|Number of pages||4|
|Journal||European Journal of Organic Chemistry|
|Publication status||Published - 16-Jun-2019|
- Phosphorus Ylides, Glycoconjugates, Glycosyl Formamides, Multi-Component Reactions, Chemical Biology, ONE-POT SYNTHESIS, ACETYLENIC ESTERS, DIMETHYL ACETYLENEDICARBOXYLATE, 3-COMPONENT REACTION, VINYLPHOSPHONIUM SALTS, TRIPHENYLPHOSPHINE, EFFICIENT, FACILE