Publication

Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography

Arif, W. M., Elsinga, P. H., Gasca-Salas, C., Versluis, M., Martínez-Fernández, R., Dierckx, R. A. J. O., Borra, R. J. H. & Luurtsema, G., 10-Aug-2020, In : Journal of controlled release : official journal of the Controlled Release Society. 324, p. 303-316 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

APA

Arif, W. M., Elsinga, P. H., Gasca-Salas, C., Versluis, M., Martínez-Fernández, R., Dierckx, R. A. J. O., Borra, R. J. H., & Luurtsema, G. (2020). Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography. Journal of controlled release : official journal of the Controlled Release Society, 324, 303-316. https://doi.org/10.1016/j.jconrel.2020.05.020

Author

Arif, Wejdan M ; Elsinga, Philip H ; Gasca-Salas, Carmen ; Versluis, Michel ; Martínez-Fernández, Raaúl ; Dierckx, Rudi A J O ; Borra, Ronald J H ; Luurtsema, Gert. / Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography. In: Journal of controlled release : official journal of the Controlled Release Society. 2020 ; Vol. 324. pp. 303-316.

Harvard

Arif, WM, Elsinga, PH, Gasca-Salas, C, Versluis, M, Martínez-Fernández, R, Dierckx, RAJO, Borra, RJH & Luurtsema, G 2020, 'Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography', Journal of controlled release : official journal of the Controlled Release Society, vol. 324, pp. 303-316. https://doi.org/10.1016/j.jconrel.2020.05.020

Standard

Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography. / Arif, Wejdan M; Elsinga, Philip H; Gasca-Salas, Carmen; Versluis, Michel; Martínez-Fernández, Raaúl; Dierckx, Rudi A J O; Borra, Ronald J H; Luurtsema, Gert.

In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 324, 10.08.2020, p. 303-316.

Research output: Contribution to journalReview articleAcademicpeer-review

Vancouver

Arif WM, Elsinga PH, Gasca-Salas C, Versluis M, Martínez-Fernández R, Dierckx RAJO et al. Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography. Journal of controlled release : official journal of the Controlled Release Society. 2020 Aug 10;324:303-316. https://doi.org/10.1016/j.jconrel.2020.05.020


BibTeX

@article{7e3bb8d7c2ae4999afa75d64d546d994,
title = "Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography",
abstract = "Focused ultrasound (FUS) is a minimally-invasive technology used for treatment of many diseases, including diseases related to the colon, uterus, prostate, and brain. Although it has been mainly used for ablative procedures, the ability of FUS to open the blood-brain barrier (BBB) presents a promising new application. However, the mechanism of BBB opening by FUS remains unclear. This review focuses on the use of FUS to open the BBB for enhancing drug delivery and investigating how Positron Emission Tomography (PET) provides insight into the underlying mechanism. ",
keywords = "FUS, microbubbles, RADIOTRACER, BBB transporters",
author = "Arif, {Wejdan M} and Elsinga, {Philip H} and Carmen Gasca-Salas and Michel Versluis and Raa{\'u}l Mart{\'i}nez-Fern{\'a}ndez and Dierckx, {Rudi A J O} and Borra, {Ronald J H} and Gert Luurtsema",
note = "Copyright {\textcopyright} 2019. Published by Elsevier B.V.",
year = "2020",
month = aug,
day = "10",
doi = "10.1016/j.jconrel.2020.05.020",
language = "English",
volume = "324",
pages = "303--316",
journal = "Journal of Controlled Release",
issn = "0168-3659",
publisher = "Elsevier Bedrijfsinformatie b.v.",

}

RIS

TY - JOUR

T1 - Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography

AU - Arif, Wejdan M

AU - Elsinga, Philip H

AU - Gasca-Salas, Carmen

AU - Versluis, Michel

AU - Martínez-Fernández, Raaúl

AU - Dierckx, Rudi A J O

AU - Borra, Ronald J H

AU - Luurtsema, Gert

N1 - Copyright © 2019. Published by Elsevier B.V.

PY - 2020/8/10

Y1 - 2020/8/10

N2 - Focused ultrasound (FUS) is a minimally-invasive technology used for treatment of many diseases, including diseases related to the colon, uterus, prostate, and brain. Although it has been mainly used for ablative procedures, the ability of FUS to open the blood-brain barrier (BBB) presents a promising new application. However, the mechanism of BBB opening by FUS remains unclear. This review focuses on the use of FUS to open the BBB for enhancing drug delivery and investigating how Positron Emission Tomography (PET) provides insight into the underlying mechanism.

AB - Focused ultrasound (FUS) is a minimally-invasive technology used for treatment of many diseases, including diseases related to the colon, uterus, prostate, and brain. Although it has been mainly used for ablative procedures, the ability of FUS to open the blood-brain barrier (BBB) presents a promising new application. However, the mechanism of BBB opening by FUS remains unclear. This review focuses on the use of FUS to open the BBB for enhancing drug delivery and investigating how Positron Emission Tomography (PET) provides insight into the underlying mechanism.

KW - FUS

KW - microbubbles

KW - RADIOTRACER

KW - BBB transporters

U2 - 10.1016/j.jconrel.2020.05.020

DO - 10.1016/j.jconrel.2020.05.020

M3 - Review article

C2 - 32428519

VL - 324

SP - 303

EP - 316

JO - Journal of Controlled Release

JF - Journal of Controlled Release

SN - 0168-3659

ER -

ID: 125784354