Publication

Flap choice does not affect complication rates or functional outcomes following extremity soft tissue sarcoma reconstruction

Slump, J., Hofer, S. O. P., Ferguson, P. C., Wunder, J. S., Griffin, A. M., Hoekstra, H. J., Bastiaannet, E. & O'Neill, A. C., Jul-2018, In : Journal of Plastic Reconstructive and Aesthetic Surgery. 71, 7, p. 989-996 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Slump, J., Hofer, S. O. P., Ferguson, P. C., Wunder, J. S., Griffin, A. M., Hoekstra, H. J., ... O'Neill, A. C. (2018). Flap choice does not affect complication rates or functional outcomes following extremity soft tissue sarcoma reconstruction. Journal of Plastic Reconstructive and Aesthetic Surgery, 71(7), 989-996. https://doi.org/10.1016/j.bjps.2018.04.002

Author

Slump, Jelena ; Hofer, Stefan O. P. ; Ferguson, Peter C. ; Wunder, Jay S. ; Griffin, Anthony M. ; Hoekstra, Harald J. ; Bastiaannet, Esther ; O'Neill, Anne C. / Flap choice does not affect complication rates or functional outcomes following extremity soft tissue sarcoma reconstruction. In: Journal of Plastic Reconstructive and Aesthetic Surgery. 2018 ; Vol. 71, No. 7. pp. 989-996.

Harvard

Slump, J, Hofer, SOP, Ferguson, PC, Wunder, JS, Griffin, AM, Hoekstra, HJ, Bastiaannet, E & O'Neill, AC 2018, 'Flap choice does not affect complication rates or functional outcomes following extremity soft tissue sarcoma reconstruction', Journal of Plastic Reconstructive and Aesthetic Surgery, vol. 71, no. 7, pp. 989-996. https://doi.org/10.1016/j.bjps.2018.04.002

Standard

Flap choice does not affect complication rates or functional outcomes following extremity soft tissue sarcoma reconstruction. / Slump, Jelena; Hofer, Stefan O. P.; Ferguson, Peter C.; Wunder, Jay S.; Griffin, Anthony M.; Hoekstra, Harald J.; Bastiaannet, Esther; O'Neill, Anne C.

In: Journal of Plastic Reconstructive and Aesthetic Surgery, Vol. 71, No. 7, 07.2018, p. 989-996.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Slump J, Hofer SOP, Ferguson PC, Wunder JS, Griffin AM, Hoekstra HJ et al. Flap choice does not affect complication rates or functional outcomes following extremity soft tissue sarcoma reconstruction. Journal of Plastic Reconstructive and Aesthetic Surgery. 2018 Jul;71(7):989-996. https://doi.org/10.1016/j.bjps.2018.04.002


BibTeX

@article{436a8fd60a10417dae45165ec695dbc8,
title = "Flap choice does not affect complication rates or functional outcomes following extremity soft tissue sarcoma reconstruction",
abstract = "Background: Flap reconstruction plays an essential role in facilitating limb preservation in patients with extremity soft tissue sarcoma (ESTS). However, the effect of flap choice on the rates of postoperative complications and functional outcomes has not been clearly established. This study directly compares the outcomes of free and pedicled flap reconstructions in patients with ESTS.Methods: Two hundred sixty-six patients who underwent flap reconstruction following ESTS resection were included. Associations between flap type and complications were determined using logistic regression analyses. Functional outcome was evaluated using the Toronto Extremity Salvage Score (TESS) and the Musculoskeletal Tumor Society Scales (MSTS).Results: There was no significant difference between complication rates in the pedicled and free flap groups (32{\%} vs. 38{\%}, p = 0.38). In the lower limb, pedicled flaps had complication rates similar to those of free flaps on univariate analysis (odds ratio [OR] = 1.12, 95{\%} confidence interval [CI] = 0.56-2.26, p = 0.75). Conversely, in the upper limb, pedicled flaps were associated with fewer complications on univariate analysis (OR = 0.31, 95{\%} CI = 0.11-0.86, p = 0.03), but this was not significant on multivariate analysis (OR = 0.45, 95{\%} CI = 0.13-1.59, p = 0.22). Obesity was a strong predictor of complications in the upper limb group on multivariate analysis (body mass index [BMI] = 30 kg/m(2), OR= 7.01, 95{\%} CI = 1.28-38.51, p = 0.03). There was no significant difference in functional outcomes between both flap groups in either upper or lower limbs.Conclusions: Postoperative complications and functional outcomes for patients undergoing free and pedicled flaps are similar in ESTS reconstruction. Selecting the most suitable reconstructive option in each individual case is paramount to preserving function while minimizing postoperative morbidity. (C) 2018 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.",
keywords = "Extremity soft tissue sarcoma, Reconstruction, Free flap, Pedicled flap, LIMB SALVAGE SURGERY, PREOPERATIVE RADIATION, RADIOTHERAPY, PREDICTORS, MANAGEMENT, RESECTION, PATIENT, TUMOR",
author = "Jelena Slump and Hofer, {Stefan O. P.} and Ferguson, {Peter C.} and Wunder, {Jay S.} and Griffin, {Anthony M.} and Hoekstra, {Harald J.} and Esther Bastiaannet and O'Neill, {Anne C.}",
year = "2018",
month = "7",
doi = "10.1016/j.bjps.2018.04.002",
language = "English",
volume = "71",
pages = "989--996",
journal = "Journal of Plastic Reconstructive and Aesthetic Surgery",
issn = "1748-6815",
publisher = "ELSEVIER SCI LTD",
number = "7",

}

RIS

TY - JOUR

T1 - Flap choice does not affect complication rates or functional outcomes following extremity soft tissue sarcoma reconstruction

AU - Slump, Jelena

AU - Hofer, Stefan O. P.

AU - Ferguson, Peter C.

AU - Wunder, Jay S.

AU - Griffin, Anthony M.

AU - Hoekstra, Harald J.

AU - Bastiaannet, Esther

AU - O'Neill, Anne C.

PY - 2018/7

Y1 - 2018/7

N2 - Background: Flap reconstruction plays an essential role in facilitating limb preservation in patients with extremity soft tissue sarcoma (ESTS). However, the effect of flap choice on the rates of postoperative complications and functional outcomes has not been clearly established. This study directly compares the outcomes of free and pedicled flap reconstructions in patients with ESTS.Methods: Two hundred sixty-six patients who underwent flap reconstruction following ESTS resection were included. Associations between flap type and complications were determined using logistic regression analyses. Functional outcome was evaluated using the Toronto Extremity Salvage Score (TESS) and the Musculoskeletal Tumor Society Scales (MSTS).Results: There was no significant difference between complication rates in the pedicled and free flap groups (32% vs. 38%, p = 0.38). In the lower limb, pedicled flaps had complication rates similar to those of free flaps on univariate analysis (odds ratio [OR] = 1.12, 95% confidence interval [CI] = 0.56-2.26, p = 0.75). Conversely, in the upper limb, pedicled flaps were associated with fewer complications on univariate analysis (OR = 0.31, 95% CI = 0.11-0.86, p = 0.03), but this was not significant on multivariate analysis (OR = 0.45, 95% CI = 0.13-1.59, p = 0.22). Obesity was a strong predictor of complications in the upper limb group on multivariate analysis (body mass index [BMI] = 30 kg/m(2), OR= 7.01, 95% CI = 1.28-38.51, p = 0.03). There was no significant difference in functional outcomes between both flap groups in either upper or lower limbs.Conclusions: Postoperative complications and functional outcomes for patients undergoing free and pedicled flaps are similar in ESTS reconstruction. Selecting the most suitable reconstructive option in each individual case is paramount to preserving function while minimizing postoperative morbidity. (C) 2018 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

AB - Background: Flap reconstruction plays an essential role in facilitating limb preservation in patients with extremity soft tissue sarcoma (ESTS). However, the effect of flap choice on the rates of postoperative complications and functional outcomes has not been clearly established. This study directly compares the outcomes of free and pedicled flap reconstructions in patients with ESTS.Methods: Two hundred sixty-six patients who underwent flap reconstruction following ESTS resection were included. Associations between flap type and complications were determined using logistic regression analyses. Functional outcome was evaluated using the Toronto Extremity Salvage Score (TESS) and the Musculoskeletal Tumor Society Scales (MSTS).Results: There was no significant difference between complication rates in the pedicled and free flap groups (32% vs. 38%, p = 0.38). In the lower limb, pedicled flaps had complication rates similar to those of free flaps on univariate analysis (odds ratio [OR] = 1.12, 95% confidence interval [CI] = 0.56-2.26, p = 0.75). Conversely, in the upper limb, pedicled flaps were associated with fewer complications on univariate analysis (OR = 0.31, 95% CI = 0.11-0.86, p = 0.03), but this was not significant on multivariate analysis (OR = 0.45, 95% CI = 0.13-1.59, p = 0.22). Obesity was a strong predictor of complications in the upper limb group on multivariate analysis (body mass index [BMI] = 30 kg/m(2), OR= 7.01, 95% CI = 1.28-38.51, p = 0.03). There was no significant difference in functional outcomes between both flap groups in either upper or lower limbs.Conclusions: Postoperative complications and functional outcomes for patients undergoing free and pedicled flaps are similar in ESTS reconstruction. Selecting the most suitable reconstructive option in each individual case is paramount to preserving function while minimizing postoperative morbidity. (C) 2018 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

KW - Extremity soft tissue sarcoma

KW - Reconstruction

KW - Free flap

KW - Pedicled flap

KW - LIMB SALVAGE SURGERY

KW - PREOPERATIVE RADIATION

KW - RADIOTHERAPY

KW - PREDICTORS

KW - MANAGEMENT

KW - RESECTION

KW - PATIENT

KW - TUMOR

U2 - 10.1016/j.bjps.2018.04.002

DO - 10.1016/j.bjps.2018.04.002

M3 - Article

VL - 71

SP - 989

EP - 996

JO - Journal of Plastic Reconstructive and Aesthetic Surgery

JF - Journal of Plastic Reconstructive and Aesthetic Surgery

SN - 1748-6815

IS - 7

ER -

ID: 75526574