Feasibility of a 2(nd) generation MR-compatible manipulator for transrectal prostate biopsy guidance

Bomers, J. G. R., Bosboom, D. G. H., Tigelaar, G. H., Sabisch, J., Futterer, J. J. & Yakar, D., Apr-2017, In : European Radiology. 27, 4, p. 1776-1782 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

  • J. G. R. Bomers
  • D. G. H. Bosboom
  • G. H. Tigelaar
  • J. Sabisch
  • J. J. Futterer
  • D. Yakar

To assess the feasibility of a 2(nd) generation MR-compatible, remote-controlled manipulator (RCM) as an aid to perform MR-guided transrectal prostate biopsy in males with suspicion of prostate cancer (PCa).

This prospective phase I study was approved by the local ethical committee and written informed consent was obtained from each patient. Twenty patients with >= 1 cancer suspicious region (CSR) with a PI-RADS score of >= 3 detected on the diagnostic multi-parametric MRI and no prior prostate treatment underwent MR-guided biopsy with the aid of the RCM. Complications were classified according to the modified Clavien system for reporting surgical complications. For evaluation of the workflow, procedure- and manipulation times were recorded.

All CSR's (n=20) were reachable with the MR-compatible RCM and the cancer detection rate was 70 %. The median procedure time was 36:44 minutes (range, 23 - 61 minutes) and the median manipulation time for needle guide movement was 5:48 minutes (range, 1:15 - 18:35 minutes). Two Clavien grade 1 complications were reported.

It is feasible and safe to perform transrectal MR-guided prostate biopsy using a MR-compatible RCM as an aid. It is a fast and efficient way to biopsy suspicious prostate lesions with a minimum number of biopsies per patient.

It is feasible to perform transrectal prostate biopsy using a MR-compatible RCM.

Using a RCM for MR-guided biopsy is safe, fast, and efficient.

All cancer suspicious regions were reachable with the RCM.

Original languageEnglish
Pages (from-to)1776-1782
Number of pages7
JournalEuropean Radiology
Issue number4
Publication statusPublished - Apr-2017


  • Prostate cancer, MRI, Biopsy, Robotics, Feasibility, GUIDED BIOPSY, ULTRASOUND FUSION, CANCER DETECTION, COHORT

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