Family environment is associated with HPA-axis activity in adolescents: The TRAILS studyMarsman, R., Nederhof, E., Rosmalen, J. G., Oldehinkel, A. J., Ormel, J. & Buitelaar, J. K., Feb-2012, In : Biological Psychology. 89, 2, p. 460-466 7 p.
Research output: Contribution to journal › Article › Academic › peer-review
The purpose of the present study was to investigate the developmental programming part of the theory of biological sensitivity to context using family environmental factors and hypothalamus-pituitary-adrenal (HPA) axis functioning. Specifically, we investigated whether perceived parenting (Rejection and Emotional Warmth) and socio-economic status (SES) predicted basal cortisol levels and the cortisol awakening response (CAR). In a population-based cohort of 1594 adolescents (mean age=11.08, SD=0.54) we assessed salivary cortisol, SES and perceived parenting. Perceived parental Emotional Warmth showed an inverse, linear association with basal cortisol levels. In addition, there was a curvilinear relationship between SES and both basal cortisol levels and the CAR. Our findings with regard to basal cortisol levels confirmed our hypothesis: lower basal HPA-axis activity in both high and low SES families compared to intermediate SES families
|Number of pages||7|
|Publication status||Published - Feb-2012|
- Adolescence, Parenting, SES, HPA-axis, Cortisol awakening response, MENTAL-HEALTH PROBLEMS, EVOLUTIONARY-DEVELOPMENTAL THEORY, PITUITARY-ADRENAL AXIS, BIOLOGICAL SENSITIVITY, STRESS REACTIVITY, EXTERNALIZING BEHAVIOR, ANTISOCIAL-BEHAVIOR, SALIVARY CORTISOL, POPULATION-SAMPLE, SOCIAL STRESS