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Factors Associated with Self-Rated Health after Kidney Transplantation: A Prospective Study

Majernikova, M., Prihodova, L., Rosenberger, J., Nagyova, I., Roland, R., Groothoff, J. W. & van Dijk, J. P., 2011, In : American Journal of Nephrology. 33, 4, p. 364-369 6 p.

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Background: This prospective study explores and compares the relationship between patients' self-rated health (SRH) after kidney transplantation (KT) at different follow-up periods and its medical and nonmedical predictors over time. Methods: Patients (n = 128) who completed a questionnaire (the SRH question of the SF-36 and the End-Stage Renal Disease Symptom Checklist - Transplantation Module) were enrolled. Clinical data were retrieved from medical files. The sample was stratified into early (n = 89) and late (n = 39) cohorts according to time since KT at baseline. Linear regression was used to identify predictors of SRH at follow-up. Results: In both cohorts, a change in glomerular filtration rate (GFR) over time remained a predictor of SRH; in the early cohort, age was an additional predictor; in the late cohort, a change in transplantation-associated psychological distress over time and the number of late acute rejection episodes during the observation period were additional predictors. Conclusions: Improvement in GFR over time predicted better SRH at each period after KT. Decreased transplantation-associated psychological distress and fewer late acute rejection episodes seemed to predict better SRH at a later follow-up period. Despite these observations, higher SRH was associated with better clinical outcomes. Copyright (C) 2011 S. Karger AG, Basel

Original languageEnglish
Pages (from-to)364-369
Number of pages6
JournalAmerican Journal of Nephrology
Volume33
Issue number4
Publication statusPublished - 2011

    Keywords

  • Kidney transplantation, Self-rated health, Glomerular filtration rate, Rejection, Immunosuppressant side effects, QUALITY-OF-LIFE, STAGE RENAL-DISEASE, LATE ACUTE REJECTION, LIVER-TRANSPLANTATION, MORTALITY, GRAFT, SF-36, DETERIORATION, PREDICTION, DIALYSIS

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