Publication

Experimental studies on the ring opening polymerization of p-dioxanone using an Al((OPr)-Pr-i)(3)-monosaccharide initiator system

Sugih, A. K., Picchioni, F. & Heeres, H. J., Jan-2009, In : European Polymer Journal. 45, 1, p. 155-164 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Sugih, A. K., Picchioni, F., & Heeres, H. J. (2009). Experimental studies on the ring opening polymerization of p-dioxanone using an Al((OPr)-Pr-i)(3)-monosaccharide initiator system. European Polymer Journal, 45(1), 155-164. https://doi.org/10.1016/j.eurpolymj.2008.10.010

Author

Sugih, Asaf Kleopas ; Picchioni, Francesco ; Heeres, Hero J. / Experimental studies on the ring opening polymerization of p-dioxanone using an Al((OPr)-Pr-i)(3)-monosaccharide initiator system. In: European Polymer Journal. 2009 ; Vol. 45, No. 1. pp. 155-164.

Harvard

Sugih, AK, Picchioni, F & Heeres, HJ 2009, 'Experimental studies on the ring opening polymerization of p-dioxanone using an Al((OPr)-Pr-i)(3)-monosaccharide initiator system', European Polymer Journal, vol. 45, no. 1, pp. 155-164. https://doi.org/10.1016/j.eurpolymj.2008.10.010

Standard

Experimental studies on the ring opening polymerization of p-dioxanone using an Al((OPr)-Pr-i)(3)-monosaccharide initiator system. / Sugih, Asaf Kleopas; Picchioni, Francesco; Heeres, Hero J.

In: European Polymer Journal, Vol. 45, No. 1, 01.2009, p. 155-164.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Sugih AK, Picchioni F, Heeres HJ. Experimental studies on the ring opening polymerization of p-dioxanone using an Al((OPr)-Pr-i)(3)-monosaccharide initiator system. European Polymer Journal. 2009 Jan;45(1):155-164. https://doi.org/10.1016/j.eurpolymj.2008.10.010


BibTeX

@article{1038a100dd1447f7b5e8ee2a7ce2a18a,
title = "Experimental studies on the ring opening polymerization of p-dioxanone using an Al((OPr)-Pr-i)(3)-monosaccharide initiator system",
abstract = "The ring opening polymerization (ROP) of p-dioxanone using a protected monosaccharide (1,2;3.4-di-O-isopropylidene-alpha-D-galactopyranose)/Al((OPr)-Pr-i)(3) initiator system to yield polydioxanone with a protected monosaccharide end-group is described. The products were synthesized at 60-100 degrees C and characterized by H-1 and C-13 NMR, and MALDI-TOF mass spectrometry. Besides the desired polydioxanone functionalised with a monosaccharide end-group, also polydioxanone with an (OPr)-Pr-i end-group was formed (20-30%). Systematic studies showed that the polymer yield is a function of the reaction temperature and the reaction time, with higher temperatures (100 degrees C) leading to lower yields. The average chain length of the polymers is between 7 and 58 repeating units and may be tuned by the monomer to monosaccharide ratio (at constant Al((OPr)-Pr-i)(3) intake). A statistical model has been developed that successfully describes the experimentally observed relation between the average chain length of the functionalized polymer and reaction parameters. (C) 2008 Elsevier Ltd. All rights reserved.",
keywords = "Biodegradable, Polyesters, Poly-p-dioxanone, Ring-opening polymerization, EPSILON-CAPROLACTONE, CYCLIC ESTERS, 1,4-DIOXAN-2-ONE, LACTONES, POLYLACTONES, MECHANISM, KINETICS, LACTIDE, BULK",
author = "Sugih, {Asaf Kleopas} and Francesco Picchioni and Heeres, {Hero J.}",
year = "2009",
month = jan,
doi = "10.1016/j.eurpolymj.2008.10.010",
language = "English",
volume = "45",
pages = "155--164",
journal = "European Polymer Journal",
issn = "0014-3057",
publisher = "PERGAMON-ELSEVIER SCIENCE LTD",
number = "1",

}

RIS

TY - JOUR

T1 - Experimental studies on the ring opening polymerization of p-dioxanone using an Al((OPr)-Pr-i)(3)-monosaccharide initiator system

AU - Sugih, Asaf Kleopas

AU - Picchioni, Francesco

AU - Heeres, Hero J.

PY - 2009/1

Y1 - 2009/1

N2 - The ring opening polymerization (ROP) of p-dioxanone using a protected monosaccharide (1,2;3.4-di-O-isopropylidene-alpha-D-galactopyranose)/Al((OPr)-Pr-i)(3) initiator system to yield polydioxanone with a protected monosaccharide end-group is described. The products were synthesized at 60-100 degrees C and characterized by H-1 and C-13 NMR, and MALDI-TOF mass spectrometry. Besides the desired polydioxanone functionalised with a monosaccharide end-group, also polydioxanone with an (OPr)-Pr-i end-group was formed (20-30%). Systematic studies showed that the polymer yield is a function of the reaction temperature and the reaction time, with higher temperatures (100 degrees C) leading to lower yields. The average chain length of the polymers is between 7 and 58 repeating units and may be tuned by the monomer to monosaccharide ratio (at constant Al((OPr)-Pr-i)(3) intake). A statistical model has been developed that successfully describes the experimentally observed relation between the average chain length of the functionalized polymer and reaction parameters. (C) 2008 Elsevier Ltd. All rights reserved.

AB - The ring opening polymerization (ROP) of p-dioxanone using a protected monosaccharide (1,2;3.4-di-O-isopropylidene-alpha-D-galactopyranose)/Al((OPr)-Pr-i)(3) initiator system to yield polydioxanone with a protected monosaccharide end-group is described. The products were synthesized at 60-100 degrees C and characterized by H-1 and C-13 NMR, and MALDI-TOF mass spectrometry. Besides the desired polydioxanone functionalised with a monosaccharide end-group, also polydioxanone with an (OPr)-Pr-i end-group was formed (20-30%). Systematic studies showed that the polymer yield is a function of the reaction temperature and the reaction time, with higher temperatures (100 degrees C) leading to lower yields. The average chain length of the polymers is between 7 and 58 repeating units and may be tuned by the monomer to monosaccharide ratio (at constant Al((OPr)-Pr-i)(3) intake). A statistical model has been developed that successfully describes the experimentally observed relation between the average chain length of the functionalized polymer and reaction parameters. (C) 2008 Elsevier Ltd. All rights reserved.

KW - Biodegradable

KW - Polyesters

KW - Poly-p-dioxanone

KW - Ring-opening polymerization

KW - EPSILON-CAPROLACTONE

KW - CYCLIC ESTERS

KW - 1,4-DIOXAN-2-ONE

KW - LACTONES

KW - POLYLACTONES

KW - MECHANISM

KW - KINETICS

KW - LACTIDE

KW - BULK

U2 - 10.1016/j.eurpolymj.2008.10.010

DO - 10.1016/j.eurpolymj.2008.10.010

M3 - Article

VL - 45

SP - 155

EP - 164

JO - European Polymer Journal

JF - European Polymer Journal

SN - 0014-3057

IS - 1

ER -

ID: 4845964