Publication

Existing Self-Replicators Can Direct the Emergence of New Ones

Altay, Y., Altay, M. & Otto, S., 14-Aug-2018, In : Chemistry. 24, 46, p. 11911-11915 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Altay, Y., Altay, M., & Otto, S. (2018). Existing Self-Replicators Can Direct the Emergence of New Ones. Chemistry, 24(46), 11911-11915. https://doi.org/10.1002/chem.201803027

Author

Altay, Yigit ; Altay, Meniz ; Otto, Sijbren. / Existing Self-Replicators Can Direct the Emergence of New Ones. In: Chemistry. 2018 ; Vol. 24, No. 46. pp. 11911-11915.

Harvard

Altay, Y, Altay, M & Otto, S 2018, 'Existing Self-Replicators Can Direct the Emergence of New Ones' Chemistry, vol. 24, no. 46, pp. 11911-11915. https://doi.org/10.1002/chem.201803027

Standard

Existing Self-Replicators Can Direct the Emergence of New Ones. / Altay, Yigit; Altay, Meniz; Otto, Sijbren.

In: Chemistry, Vol. 24, No. 46, 14.08.2018, p. 11911-11915.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Altay Y, Altay M, Otto S. Existing Self-Replicators Can Direct the Emergence of New Ones. Chemistry. 2018 Aug 14;24(46):11911-11915. https://doi.org/10.1002/chem.201803027


BibTeX

@article{6ee0f2c8fecd43d3a8142156b4aafe7a,
title = "Existing Self-Replicators Can Direct the Emergence of New Ones",
abstract = "The study of the interplay between different self-replicating molecules constitutes an important new phase in the synthesis of life and in unravelling the origin of life. Here we show how existing replicators can direct the nature of a newly formed replicator. Starting from the same building block, 6-ring replicators formed when the mixture was exposed to pre-existing 6-membered replicators, while pre-formed 8-membered replicators funneled the building block into 8-ring replicators. Not only ring size, but also the mode of assembly of the rings into stacks was inherited from the pre-existing replicators. These results show that the nature of self-replicating molecules can be strongly influenced by the interplay between different self-replicators, overriding preferences innate to the structure of the building block.",
keywords = "DYNAMIC COMBINATORIAL CHEMISTRY, SYNTHETIC REPLICATORS, MOLECULAR NETWORKS, SYSTEMS CHEMISTRY, LIBRARY, ROAD, COMPETITION, MECHANISM, EVOLUTION, DRIVES",
author = "Yigit Altay and Meniz Altay and Sijbren Otto",
note = "{\circledC} 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2018",
month = "8",
day = "14",
doi = "10.1002/chem.201803027",
language = "English",
volume = "24",
pages = "11911--11915",
journal = "Chemistry",
issn = "0947-6539",
publisher = "WILEY-V C H VERLAG GMBH",
number = "46",

}

RIS

TY - JOUR

T1 - Existing Self-Replicators Can Direct the Emergence of New Ones

AU - Altay, Yigit

AU - Altay, Meniz

AU - Otto, Sijbren

N1 - © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

PY - 2018/8/14

Y1 - 2018/8/14

N2 - The study of the interplay between different self-replicating molecules constitutes an important new phase in the synthesis of life and in unravelling the origin of life. Here we show how existing replicators can direct the nature of a newly formed replicator. Starting from the same building block, 6-ring replicators formed when the mixture was exposed to pre-existing 6-membered replicators, while pre-formed 8-membered replicators funneled the building block into 8-ring replicators. Not only ring size, but also the mode of assembly of the rings into stacks was inherited from the pre-existing replicators. These results show that the nature of self-replicating molecules can be strongly influenced by the interplay between different self-replicators, overriding preferences innate to the structure of the building block.

AB - The study of the interplay between different self-replicating molecules constitutes an important new phase in the synthesis of life and in unravelling the origin of life. Here we show how existing replicators can direct the nature of a newly formed replicator. Starting from the same building block, 6-ring replicators formed when the mixture was exposed to pre-existing 6-membered replicators, while pre-formed 8-membered replicators funneled the building block into 8-ring replicators. Not only ring size, but also the mode of assembly of the rings into stacks was inherited from the pre-existing replicators. These results show that the nature of self-replicating molecules can be strongly influenced by the interplay between different self-replicators, overriding preferences innate to the structure of the building block.

KW - DYNAMIC COMBINATORIAL CHEMISTRY

KW - SYNTHETIC REPLICATORS

KW - MOLECULAR NETWORKS

KW - SYSTEMS CHEMISTRY

KW - LIBRARY

KW - ROAD

KW - COMPETITION

KW - MECHANISM

KW - EVOLUTION

KW - DRIVES

U2 - 10.1002/chem.201803027

DO - 10.1002/chem.201803027

M3 - Article

VL - 24

SP - 11911

EP - 11915

JO - Chemistry

JF - Chemistry

SN - 0947-6539

IS - 46

ER -

ID: 93869131