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Existing Self-Replicators Can Direct the Emergence of New Ones

Altay, Y., Altay, M. & Otto, S., 14-Aug-2018, In : Chemistry. 24, 46, p. 11911-11915 5 p.

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DOI

The study of the interplay between different self-replicating molecules constitutes an important new phase in the synthesis of life and in unravelling the origin of life. Here we show how existing replicators can direct the nature of a newly formed replicator. Starting from the same building block, 6-ring replicators formed when the mixture was exposed to pre-existing 6-membered replicators, while pre-formed 8-membered replicators funneled the building block into 8-ring replicators. Not only ring size, but also the mode of assembly of the rings into stacks was inherited from the pre-existing replicators. These results show that the nature of self-replicating molecules can be strongly influenced by the interplay between different self-replicators, overriding preferences innate to the structure of the building block.

Original languageEnglish
Pages (from-to)11911-11915
Number of pages5
JournalChemistry
Volume24
Issue number46
Publication statusPublished - 14-Aug-2018

    Keywords

  • DYNAMIC COMBINATORIAL CHEMISTRY, SYNTHETIC REPLICATORS, MOLECULAR NETWORKS, SYSTEMS CHEMISTRY, LIBRARY, ROAD, COMPETITION, MECHANISM, EVOLUTION, DRIVES

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