Excess drug prescriptions during influenza and RSV seasons in the Netherlands: Potential implications for extended influenza vaccinationAssink, M. D., Kiewiet, J. P., Rozenbaum, M. H., van den Berg, P. B., Hak, E., Buskens, E. J., Wilschut, J. C., Kroes, A. C. & Postma, M. J., 11-Feb-2009, In : Vaccine. 27, 7, p. 1119-1126 8 p.
Research output: Contribution to journal › Article › Academic › peer-review
Influenza and respiratory syncytial Virus (RSV) infections are responsible for considerable morbidity, mortality and health-care resource use. For the Netherlands, we estimated age and risk-group Specific numbers of antibiotics, otologicals and cardiovascular prescriptions per 10,000 person-years during periods with elevated activity of influenza or RSV, and compared these with peri-season rates. Data were taken from the University of Groningen in-house prescription database (www.iadb.nl) and Virological Surveillance for the period 1998-2006. During influenza and RSV periods excess antibiotic prescriptions were estimated for all age groups. In the age groups 0-1 and 2-4 years. excess antibiotic prescriptions during periods with elevated RSV activity (65% and 59% of peri-seasonal rates) exceeded the surpluses estimated during the influenza-activity periods (24% and 34% of peri-seasonal rates) while for otologicals excess prescriptions were higher for influenza (22% and 27%) than for RSV (14% and 17%). Among persons of 50 years and older, notably those without medical high-risk conditions, excess prescriptions for cardiovascular medications were estimated during the influenza periods at approximately 10% (this was also already seen in persons aged 45-49). Our results may have implications for influenza vaccination policies. In particular, extension of influenza vaccination to groups of non-elderly adults and young children may lower excess prescriptions during these influenza periods for all three types of drug prescriptions investigated. (C) 2008 Elsevier Ltd. All rights reserved.
|Number of pages||8|
|Publication status||Published - 11-Feb-2009|
- Respiratory syncytial viruses, Influenza viruses, Excess prescriptions, RESPIRATORY SYNCYTIAL-VIRUS, ACUTE OTITIS-MEDIA, YOUNG-CHILDREN, PARAINFLUENZA VIRUSES, ELDERLY-PEOPLE, HOSPITALIZATIONS, MORBIDITY, MORTALITY, INFECTION, DISEASE