Publication

Evolutionary applications of MIRs and SINEs

Buchanan, F., Crawford, A., Strobeck, C., Palsboll, P. & Plante, Y., Feb-1999, In : Animal genetics. 30, 1, p. 47-50 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Buchanan, F., Crawford, A., Strobeck, C., Palsboll, P., & Plante, Y. (1999). Evolutionary applications of MIRs and SINEs. Animal genetics, 30(1), 47-50. https://doi.org/10.1046/j.1365-2052.1999.00388.x

Author

Buchanan, F ; Crawford, A ; Strobeck, C ; Palsboll, P ; Plante, Y. / Evolutionary applications of MIRs and SINEs. In: Animal genetics. 1999 ; Vol. 30, No. 1. pp. 47-50.

Harvard

Buchanan, F, Crawford, A, Strobeck, C, Palsboll, P & Plante, Y 1999, 'Evolutionary applications of MIRs and SINEs', Animal genetics, vol. 30, no. 1, pp. 47-50. https://doi.org/10.1046/j.1365-2052.1999.00388.x

Standard

Evolutionary applications of MIRs and SINEs. / Buchanan, F; Crawford, A; Strobeck, C; Palsboll, P; Plante, Y.

In: Animal genetics, Vol. 30, No. 1, 02.1999, p. 47-50.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Buchanan F, Crawford A, Strobeck C, Palsboll P, Plante Y. Evolutionary applications of MIRs and SINEs. Animal genetics. 1999 Feb;30(1):47-50. https://doi.org/10.1046/j.1365-2052.1999.00388.x


BibTeX

@article{ab0f8aaad7ee4322b70e5573e3572c13,
title = "Evolutionary applications of MIRs and SINEs",
abstract = "It is believed that short interspersed elements (SINEs) are irreversibly inserted into genomes. We use this concept to try to deduce the evolution of whales using sequence and hybridization studies. The observation that microsatellites are associated with SINEs lead us to screen sequences surrounding cetacean microsatellites for artiodactyl-derived SINEs. Two sequences that were thought to be cetacean SINEs and the bovine SINE were aligned for comparison to sequences flanking microsatellites from ungulates. The bovine SINE was observed only in ruminants while CetSINE1 and 2 were found in mammals. Hybridization studies using these three SINEs revealed that CetSINE1 was found in all ungulates and cetaceans with the strongest hybridization signal observed in the hippopotamus and beluga; CetSINE2 hybridized to all ungulate suborders, while the bovine SINE was only observed in Ruminantia. It is proposed that these putative SINEs are not 'generic' SINEs but mammalian-wide interspersed repeats (MIRs). Caution is urged: what initially appears to be a SINE may instead be a MIR and have reduced evolutionary resolving power.",
keywords = "artiodactyl, cetacean, mammalian-wide interspersed repeat, short interspersed element, MOLECULAR EVIDENCE, MICROSATELLITES, RETROPOSONS, CETACEANS",
author = "F Buchanan and A Crawford and C Strobeck and P Palsboll and Y Plante",
year = "1999",
month = "2",
doi = "10.1046/j.1365-2052.1999.00388.x",
language = "English",
volume = "30",
pages = "47--50",
journal = "Animal genetics",
issn = "0268-9146",
number = "1",

}

RIS

TY - JOUR

T1 - Evolutionary applications of MIRs and SINEs

AU - Buchanan, F

AU - Crawford, A

AU - Strobeck, C

AU - Palsboll, P

AU - Plante, Y

PY - 1999/2

Y1 - 1999/2

N2 - It is believed that short interspersed elements (SINEs) are irreversibly inserted into genomes. We use this concept to try to deduce the evolution of whales using sequence and hybridization studies. The observation that microsatellites are associated with SINEs lead us to screen sequences surrounding cetacean microsatellites for artiodactyl-derived SINEs. Two sequences that were thought to be cetacean SINEs and the bovine SINE were aligned for comparison to sequences flanking microsatellites from ungulates. The bovine SINE was observed only in ruminants while CetSINE1 and 2 were found in mammals. Hybridization studies using these three SINEs revealed that CetSINE1 was found in all ungulates and cetaceans with the strongest hybridization signal observed in the hippopotamus and beluga; CetSINE2 hybridized to all ungulate suborders, while the bovine SINE was only observed in Ruminantia. It is proposed that these putative SINEs are not 'generic' SINEs but mammalian-wide interspersed repeats (MIRs). Caution is urged: what initially appears to be a SINE may instead be a MIR and have reduced evolutionary resolving power.

AB - It is believed that short interspersed elements (SINEs) are irreversibly inserted into genomes. We use this concept to try to deduce the evolution of whales using sequence and hybridization studies. The observation that microsatellites are associated with SINEs lead us to screen sequences surrounding cetacean microsatellites for artiodactyl-derived SINEs. Two sequences that were thought to be cetacean SINEs and the bovine SINE were aligned for comparison to sequences flanking microsatellites from ungulates. The bovine SINE was observed only in ruminants while CetSINE1 and 2 were found in mammals. Hybridization studies using these three SINEs revealed that CetSINE1 was found in all ungulates and cetaceans with the strongest hybridization signal observed in the hippopotamus and beluga; CetSINE2 hybridized to all ungulate suborders, while the bovine SINE was only observed in Ruminantia. It is proposed that these putative SINEs are not 'generic' SINEs but mammalian-wide interspersed repeats (MIRs). Caution is urged: what initially appears to be a SINE may instead be a MIR and have reduced evolutionary resolving power.

KW - artiodactyl

KW - cetacean

KW - mammalian-wide interspersed repeat

KW - short interspersed element

KW - MOLECULAR EVIDENCE

KW - MICROSATELLITES

KW - RETROPOSONS

KW - CETACEANS

U2 - 10.1046/j.1365-2052.1999.00388.x

DO - 10.1046/j.1365-2052.1999.00388.x

M3 - Article

VL - 30

SP - 47

EP - 50

JO - Animal genetics

JF - Animal genetics

SN - 0268-9146

IS - 1

ER -

ID: 15730542