Evaluation of continuous beam rescanning versus pulsed beam in pencil beam scanned proton therapy for lung tumours

Ribeiro, C. O., Terpstra, J., Janssens, G., Langendijk, J. A., Both, S., Muijs, C. T., Wijsman, R., Knopf, A-C. & Meijers, A., 7-Dec-2020, In : Physics in Medicine and Biology. 65, 23, 9 p., ARTN 23NT01.

Research output: Contribution to journalArticleAcademicpeer-review

The treatment of moving targets with pencil beam scanned proton therapy (PBS-PT) may rely on rescanning strategies to smooth out motion induced dosimetric disturbances. PBS-PT machines, such as Proteus (R) Plus (PPlus) and Proteus (R) One (POne), deliver a continuous or a pulsed beam, respectively. In PPlus, scaled (or no) rescanning can be applied, while POne implies intrinsic 'rescanning' due to its pulsed delivery. We investigated the efficacy of these PBS-PT delivery types for the treatment of lung tumours. In general, clinically acceptable plans were achieved, and PPlus and POne showed similar effectiveness.

Original languageEnglish
Article numberARTN 23NT01
Number of pages9
JournalPhysics in Medicine and Biology
Issue number23
Early online date2020
Publication statusPublished - 7-Dec-2020


  • pencil beam scanned proton therapy, lung cancer, continuous beam, pulsed beam, rescanning, 4D robustness evaluation, CLINICAL IMPLEMENTATION, ROBUSTNESS EVALUATION, RANGE UNCERTAINTIES, MOVING TARGETS, SPOT SIZE, MOTION, RADIOTHERAPY, SETUP, 4D, OPTIMIZATION

ID: 144178061