Publication

Enzymatic Biodiesel Synthesis by the Biphasic Esterification of Oleic Acid and 1-Butanol in Microreactors

Hommes, A., de Wit, T., Euverink, G-J. & Yue, J., 28-Aug-2019, In : Industrial & Engineering Chemistry Research. 58, 34, p. 15432-15444 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Hommes, A., de Wit, T., Euverink, G-J., & Yue, J. (2019). Enzymatic Biodiesel Synthesis by the Biphasic Esterification of Oleic Acid and 1-Butanol in Microreactors. Industrial & Engineering Chemistry Research, 58(34), 15432-15444. https://doi.org/10.1021/acs.iecr.9b02693, https://doi.org/10.1021/acs.iecr.9b02693

Author

Hommes, Arne ; de Wit, Tom ; Euverink, Gert-Jan ; Yue, Jun. / Enzymatic Biodiesel Synthesis by the Biphasic Esterification of Oleic Acid and 1-Butanol in Microreactors. In: Industrial & Engineering Chemistry Research. 2019 ; Vol. 58, No. 34. pp. 15432-15444.

Harvard

Hommes, A, de Wit, T, Euverink, G-J & Yue, J 2019, 'Enzymatic Biodiesel Synthesis by the Biphasic Esterification of Oleic Acid and 1-Butanol in Microreactors' Industrial & Engineering Chemistry Research, vol. 58, no. 34, pp. 15432-15444. https://doi.org/10.1021/acs.iecr.9b02693, https://doi.org/10.1021/acs.iecr.9b02693

Standard

Enzymatic Biodiesel Synthesis by the Biphasic Esterification of Oleic Acid and 1-Butanol in Microreactors. / Hommes, Arne; de Wit, Tom; Euverink, Gert-Jan; Yue, Jun.

In: Industrial & Engineering Chemistry Research, Vol. 58, No. 34, 28.08.2019, p. 15432-15444.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Hommes A, de Wit T, Euverink G-J, Yue J. Enzymatic Biodiesel Synthesis by the Biphasic Esterification of Oleic Acid and 1-Butanol in Microreactors. Industrial & Engineering Chemistry Research. 2019 Aug 28;58(34):15432-15444. https://doi.org/10.1021/acs.iecr.9b02693, https://doi.org/10.1021/acs.iecr.9b02693


BibTeX

@article{446acc8047804b588c52aa950a363e0d,
title = "Enzymatic Biodiesel Synthesis by the Biphasic Esterification of Oleic Acid and 1-Butanol in Microreactors",
abstract = "The enzymatic esterification of oleic acid and 1-butanol to butyl oleate was performed in an aqueous-organic system in capillary microreactors with various inner diameters operated under slug flow. The free Rhizomucor miehei lipase in the aqueous phase was used as catalyst and n-heptane as the organic solvent. A close to 100{\%} yield of butyl oleate could be achieved in the microreactor made of polytetrafluoroethylene within 30 min residence time at 30 °C. The reaction rate is well described by the existing kinetic model based on a Ping Pong Bi Bi mechanism with competitive inhibition of 1-butanol. This model was extended to describe the effect of the interfacial area and aqueous to organic flow ratio in microreactors. By performing the reaction at low aqueous to organic flow ratios in hydrophilic microreactors (e.g., made of stainless steel), the enzyme turnover number could be enhanced significantly making it promising for process intensification.",
author = "Arne Hommes and {de Wit}, Tom and Gert-Jan Euverink and Jun Yue",
year = "2019",
month = "8",
day = "28",
doi = "10.1021/acs.iecr.9b02693",
language = "English",
volume = "58",
pages = "15432--15444",
journal = "Industrial and Engineering Chemistry Research",
issn = "0888-5885",
publisher = "AMER CHEMICAL SOC",
number = "34",

}

RIS

TY - JOUR

T1 - Enzymatic Biodiesel Synthesis by the Biphasic Esterification of Oleic Acid and 1-Butanol in Microreactors

AU - Hommes, Arne

AU - de Wit, Tom

AU - Euverink, Gert-Jan

AU - Yue, Jun

PY - 2019/8/28

Y1 - 2019/8/28

N2 - The enzymatic esterification of oleic acid and 1-butanol to butyl oleate was performed in an aqueous-organic system in capillary microreactors with various inner diameters operated under slug flow. The free Rhizomucor miehei lipase in the aqueous phase was used as catalyst and n-heptane as the organic solvent. A close to 100% yield of butyl oleate could be achieved in the microreactor made of polytetrafluoroethylene within 30 min residence time at 30 °C. The reaction rate is well described by the existing kinetic model based on a Ping Pong Bi Bi mechanism with competitive inhibition of 1-butanol. This model was extended to describe the effect of the interfacial area and aqueous to organic flow ratio in microreactors. By performing the reaction at low aqueous to organic flow ratios in hydrophilic microreactors (e.g., made of stainless steel), the enzyme turnover number could be enhanced significantly making it promising for process intensification.

AB - The enzymatic esterification of oleic acid and 1-butanol to butyl oleate was performed in an aqueous-organic system in capillary microreactors with various inner diameters operated under slug flow. The free Rhizomucor miehei lipase in the aqueous phase was used as catalyst and n-heptane as the organic solvent. A close to 100% yield of butyl oleate could be achieved in the microreactor made of polytetrafluoroethylene within 30 min residence time at 30 °C. The reaction rate is well described by the existing kinetic model based on a Ping Pong Bi Bi mechanism with competitive inhibition of 1-butanol. This model was extended to describe the effect of the interfacial area and aqueous to organic flow ratio in microreactors. By performing the reaction at low aqueous to organic flow ratios in hydrophilic microreactors (e.g., made of stainless steel), the enzyme turnover number could be enhanced significantly making it promising for process intensification.

U2 - 10.1021/acs.iecr.9b02693

DO - 10.1021/acs.iecr.9b02693

M3 - Article

VL - 58

SP - 15432

EP - 15444

JO - Industrial and Engineering Chemistry Research

JF - Industrial and Engineering Chemistry Research

SN - 0888-5885

IS - 34

ER -

ID: 92196890