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Embryonic growth rate affects telomere attrition: An experiment in a wild bird

Vedder, O., Verhulst, S., Zuidersma, E. & Bouwhuis, S., 10-Aug-2018, In : Journal of Experimental Biology. 221, 15, 4 p., 181586.

Research output: Contribution to journalArticleAcademicpeer-review

High growth rate is associated with a short lifespan, but the physiological basis for this trade-off is not well known. Telomere length predicts individual lifespan and in this study we investigated whether embryonic growth rate, manipulated using incubation temperature, affects erythrocyte telomere length in a wild bird species, the common tern (Sterna hirundo). A 1 degrees C lower incubation temperature decreased growth rate by 5%, without affecting size at hatching. The slower growth was associated with an average telomere length that was 147 base pairs longer at hatching. If carried through to adulthood, this effect would correspond with an approximately 3 year longer lifespan. Our results thus suggest that an effect of growth rate on lifespan may be mediated by telomere dynamics or a physiological process reflected by telomere length.

Original languageEnglish
Article number181586
Number of pages4
JournalJournal of Experimental Biology
Volume221
Issue number15
Publication statusPublished - 10-Aug-2018

    Keywords

  • Ageing, Embryonic development, Cell division, Life-history trade-off, Lifespan, Senescence, COMMON TERNS, LIFE-SPAN, LENGTH, TEMPERATURE, TURNOVER, TIME, AGE

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