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Early neonatal morbidities and neurological functioning of preterm infants 2 weeks after birth

Hempenius, M. A., Verhagen, E. A., Tanis, J. C., Einspieler, C. & Bos, A. F., Nov-2018, In : Journal of perinatology. 38, 11, p. 1518-1525 8 p.

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  • Early neonatal morbidities and neurological functioning

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DOI

Objective: To determine the association between potential neonatal risk factors and the quality of general movements (GMs) in preterm infants.

Study design: Prospective cohort study in 67 preterm infants. From video recordings made on Days 8 and 15, we scored the GMs as normal/abnormal and detailed aspects using the general movement optimality score (GMOS). Risk factors included respiratory insufficiency requiring mechanical ventilation, patent ductus arteriosus (PDA), and abnormal blood glucose levels. We used multiple regression analyses.

Result: On Day 8 after birth, the presence of a PDA remained in the multivariable model, explaining 17.1% of the variance in GMOS (beta, -0.414). On Day 15, duration of mechanical ventilation and frequency of hypoglycemic episodes explained 38.8% of the variance (betas, -0.382 and -0.466, respectively).

Conclusion: In preterm infants, PDA, duration of mechanical ventilation, and frequency of hypoglycemic episodes were associated with poorer neurological functioning during the first 2 weeks after birth.

Original languageEnglish
Pages (from-to)1518-1525
Number of pages8
JournalJournal of perinatology
Volume38
Issue number11
Publication statusPublished - Nov-2018

    Keywords

  • PATENT DUCTUS-ARTERIOSUS, GENERAL MOVEMENTS, NEURODEVELOPMENTAL OUTCOMES, WEIGHT INFANTS, QUALITATIVE CHANGES, CEREBRAL-PALSY, BRAIN-LESIONS, HYPOGLYCEMIA, DYSFUNCTION, CHILDREN

ID: 76434342