Publication

Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders

Fuermaier, A. B. M., Piersma, D., de Waard, D., Davidse, R. J., de Groot, J., Doumen, M. J. A., Bredewoud, R. A., Claesen, R., Lemstra, A. W., Scheltens, P., Vermeeren, A., Ponds, R., Verhey, F., De Deyn, P. P., Brouwer, W. H. & Tucha, O., 2019, In : Journal of Alzheimer’s Disease. 69, 4, p. 1019-1030 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Fuermaier, A. B. M., Piersma, D., de Waard, D., Davidse, R. J., de Groot, J., Doumen, M. J. A., ... Tucha, O. (2019). Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders. Journal of Alzheimer’s Disease, 69(4), 1019-1030. https://doi.org/10.3233/JAD-181095

Author

Fuermaier, Anselm B. M. ; Piersma, Dafne ; de Waard, Dick ; Davidse, Ragnhild J. ; de Groot, Jolieke ; Doumen, Michelle J. A. ; Bredewoud, Ruud A. ; Claesen, René ; Lemstra, Afina W. ; Scheltens, Philip ; Vermeeren, Annemiek ; Ponds, Rudolf ; Verhey, Frans ; De Deyn, Peter Paul ; Brouwer, Wiebo H. ; Tucha, Oliver. / Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders. In: Journal of Alzheimer’s Disease. 2019 ; Vol. 69, No. 4. pp. 1019-1030.

Harvard

Fuermaier, ABM, Piersma, D, de Waard, D, Davidse, RJ, de Groot, J, Doumen, MJA, Bredewoud, RA, Claesen, R, Lemstra, AW, Scheltens, P, Vermeeren, A, Ponds, R, Verhey, F, De Deyn, PP, Brouwer, WH & Tucha, O 2019, 'Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders', Journal of Alzheimer’s Disease, vol. 69, no. 4, pp. 1019-1030. https://doi.org/10.3233/JAD-181095

Standard

Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders. / Fuermaier, Anselm B. M.; Piersma, Dafne; de Waard, Dick; Davidse, Ragnhild J.; de Groot, Jolieke; Doumen, Michelle J. A.; Bredewoud, Ruud A.; Claesen, René; Lemstra, Afina W.; Scheltens, Philip; Vermeeren, Annemiek; Ponds, Rudolf; Verhey, Frans; De Deyn, Peter Paul; Brouwer, Wiebo H.; Tucha, Oliver.

In: Journal of Alzheimer’s Disease, Vol. 69, No. 4, 2019, p. 1019-1030.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Fuermaier ABM, Piersma D, de Waard D, Davidse RJ, de Groot J, Doumen MJA et al. Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders. Journal of Alzheimer’s Disease. 2019;69(4):1019-1030. https://doi.org/10.3233/JAD-181095


BibTeX

@article{d67a8f9818934269a761b44838955ab4,
title = "Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders",
abstract = "Background/Objective: Neurodegenerative disorders impact fitness to drive of older drivers, but on-road driving studies investigating patients with different neurodegenerative disorders are scarce. A variety of driving errors have been reported in patients with Alzheimer's disease (AD), but it is unclear which types of driving errors occur most frequently. Moreover, patients with other neurodegenerative disorders than AD typically present with different symptoms and impairments, therefore different driving errors may be expected.Methods: Patients with AD (n = 80), patients with other neurodegenerative disorders with cognitive decline (i.e., vascular dementia, frontotemporal dementia, dementia with Lewybodies/Parkinson's disease, n = 59), and healthy older drivers (n = 45) participated in a fitness-to-drive assessment study including on-road driving.Results: Patients with AD performed significantly worse than healthy older drivers on operational, tactical, visual, and global aspects of on-road driving. In patients with AD, on-road measures were significantly associated with 'off-road' measures. Patients with neurodegenerative disorders other than AD showed large overlap in the types of driving errors. Several driving errors were identified that appear to be characteristic for patients with particular neurodegenerative disorders.Conclusion: Patients from each group of neurodegenerative disorders commonly display tactical driving errors regarding lane positioning, slow driving, observation of the blind spot, and scanning behavior. Several other tactical and operational driving errors, including not communicating with cyclists and unsteady steering, were more frequently observed in patients with nonAD neurodegenerative disorders. These findings have implications for on-road and 'off-road' fitness-to-drive assessments for patients with neurodegenerative disorders with cognitive decline.",
keywords = "Alzheimer's disease, automobile driving, cognitive decline, frontotemporal dementia, dementia with Lewy bodies, neurodegenerative diseases, Parkinson's disease, vascular dementia, PARKINSONS-DISEASE, CLINICAL-DIAGNOSIS, ROAD TEST, PERFORMANCE, DEMENTIA, DRIVERS, ACCURACY, CRITERIA, FITNESS, PEOPLE",
author = "Fuermaier, {Anselm B. M.} and Dafne Piersma and {de Waard}, Dick and Davidse, {Ragnhild J.} and {de Groot}, Jolieke and Doumen, {Michelle J. A.} and Bredewoud, {Ruud A.} and Ren{\'e} Claesen and Lemstra, {Afina W.} and Philip Scheltens and Annemiek Vermeeren and Rudolf Ponds and Frans Verhey and {De Deyn}, {Peter Paul} and Brouwer, {Wiebo H.} and Oliver Tucha",
year = "2019",
doi = "10.3233/JAD-181095",
language = "English",
volume = "69",
pages = "1019--1030",
journal = "Journal of Alzheimer’s Disease",
issn = "1875-8908",
publisher = "IOS Press",
number = "4",

}

RIS

TY - JOUR

T1 - Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders

AU - Fuermaier, Anselm B. M.

AU - Piersma, Dafne

AU - de Waard, Dick

AU - Davidse, Ragnhild J.

AU - de Groot, Jolieke

AU - Doumen, Michelle J. A.

AU - Bredewoud, Ruud A.

AU - Claesen, René

AU - Lemstra, Afina W.

AU - Scheltens, Philip

AU - Vermeeren, Annemiek

AU - Ponds, Rudolf

AU - Verhey, Frans

AU - De Deyn, Peter Paul

AU - Brouwer, Wiebo H.

AU - Tucha, Oliver

PY - 2019

Y1 - 2019

N2 - Background/Objective: Neurodegenerative disorders impact fitness to drive of older drivers, but on-road driving studies investigating patients with different neurodegenerative disorders are scarce. A variety of driving errors have been reported in patients with Alzheimer's disease (AD), but it is unclear which types of driving errors occur most frequently. Moreover, patients with other neurodegenerative disorders than AD typically present with different symptoms and impairments, therefore different driving errors may be expected.Methods: Patients with AD (n = 80), patients with other neurodegenerative disorders with cognitive decline (i.e., vascular dementia, frontotemporal dementia, dementia with Lewybodies/Parkinson's disease, n = 59), and healthy older drivers (n = 45) participated in a fitness-to-drive assessment study including on-road driving.Results: Patients with AD performed significantly worse than healthy older drivers on operational, tactical, visual, and global aspects of on-road driving. In patients with AD, on-road measures were significantly associated with 'off-road' measures. Patients with neurodegenerative disorders other than AD showed large overlap in the types of driving errors. Several driving errors were identified that appear to be characteristic for patients with particular neurodegenerative disorders.Conclusion: Patients from each group of neurodegenerative disorders commonly display tactical driving errors regarding lane positioning, slow driving, observation of the blind spot, and scanning behavior. Several other tactical and operational driving errors, including not communicating with cyclists and unsteady steering, were more frequently observed in patients with nonAD neurodegenerative disorders. These findings have implications for on-road and 'off-road' fitness-to-drive assessments for patients with neurodegenerative disorders with cognitive decline.

AB - Background/Objective: Neurodegenerative disorders impact fitness to drive of older drivers, but on-road driving studies investigating patients with different neurodegenerative disorders are scarce. A variety of driving errors have been reported in patients with Alzheimer's disease (AD), but it is unclear which types of driving errors occur most frequently. Moreover, patients with other neurodegenerative disorders than AD typically present with different symptoms and impairments, therefore different driving errors may be expected.Methods: Patients with AD (n = 80), patients with other neurodegenerative disorders with cognitive decline (i.e., vascular dementia, frontotemporal dementia, dementia with Lewybodies/Parkinson's disease, n = 59), and healthy older drivers (n = 45) participated in a fitness-to-drive assessment study including on-road driving.Results: Patients with AD performed significantly worse than healthy older drivers on operational, tactical, visual, and global aspects of on-road driving. In patients with AD, on-road measures were significantly associated with 'off-road' measures. Patients with neurodegenerative disorders other than AD showed large overlap in the types of driving errors. Several driving errors were identified that appear to be characteristic for patients with particular neurodegenerative disorders.Conclusion: Patients from each group of neurodegenerative disorders commonly display tactical driving errors regarding lane positioning, slow driving, observation of the blind spot, and scanning behavior. Several other tactical and operational driving errors, including not communicating with cyclists and unsteady steering, were more frequently observed in patients with nonAD neurodegenerative disorders. These findings have implications for on-road and 'off-road' fitness-to-drive assessments for patients with neurodegenerative disorders with cognitive decline.

KW - Alzheimer's disease

KW - automobile driving

KW - cognitive decline

KW - frontotemporal dementia

KW - dementia with Lewy bodies

KW - neurodegenerative diseases

KW - Parkinson's disease

KW - vascular dementia

KW - PARKINSONS-DISEASE

KW - CLINICAL-DIAGNOSIS

KW - ROAD TEST

KW - PERFORMANCE

KW - DEMENTIA

KW - DRIVERS

KW - ACCURACY

KW - CRITERIA

KW - FITNESS

KW - PEOPLE

U2 - 10.3233/JAD-181095

DO - 10.3233/JAD-181095

M3 - Article

VL - 69

SP - 1019

EP - 1030

JO - Journal of Alzheimer’s Disease

JF - Journal of Alzheimer’s Disease

SN - 1875-8908

IS - 4

ER -

ID: 81813718