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Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders

Fuermaier, A. B. M., Piersma, D., de Waard, D., Davidse, R. J., de Groot, J., Doumen, M. J. A., Bredewoud, R. A., Claesen, R., Lemstra, A. W., Scheltens, P., Vermeeren, A., Ponds, R., Verhey, F., De Deyn, P. P., Brouwer, W. H. & Tucha, O., 2019, In : Journal of Alzheimer’s Disease. 69, 4, p. 1019-1030 12 p.

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  • Driving Difficulties Among Patients with Alzheimer’s Disease and Other Neurodegenerative Disorders

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DOI

Background/Objective: Neurodegenerative disorders impact fitness to drive of older drivers, but on-road driving studies investigating patients with different neurodegenerative disorders are scarce. A variety of driving errors have been reported in patients with Alzheimer's disease (AD), but it is unclear which types of driving errors occur most frequently. Moreover, patients with other neurodegenerative disorders than AD typically present with different symptoms and impairments, therefore different driving errors may be expected.

Methods: Patients with AD (n = 80), patients with other neurodegenerative disorders with cognitive decline (i.e., vascular dementia, frontotemporal dementia, dementia with Lewybodies/Parkinson's disease, n = 59), and healthy older drivers (n = 45) participated in a fitness-to-drive assessment study including on-road driving.

Results: Patients with AD performed significantly worse than healthy older drivers on operational, tactical, visual, and global aspects of on-road driving. In patients with AD, on-road measures were significantly associated with 'off-road' measures. Patients with neurodegenerative disorders other than AD showed large overlap in the types of driving errors. Several driving errors were identified that appear to be characteristic for patients with particular neurodegenerative disorders.

Conclusion: Patients from each group of neurodegenerative disorders commonly display tactical driving errors regarding lane positioning, slow driving, observation of the blind spot, and scanning behavior. Several other tactical and operational driving errors, including not communicating with cyclists and unsteady steering, were more frequently observed in patients with nonAD neurodegenerative disorders. These findings have implications for on-road and 'off-road' fitness-to-drive assessments for patients with neurodegenerative disorders with cognitive decline.

Original languageEnglish
Pages (from-to)1019-1030
Number of pages12
JournalJournal of Alzheimer’s Disease
Volume69
Issue number4
Early online date30-Apr-2019
Publication statusPublished - 2019

    Keywords

  • Alzheimer's disease, automobile driving, cognitive decline, frontotemporal dementia, dementia with Lewy bodies, neurodegenerative diseases, Parkinson's disease, vascular dementia, PARKINSONS-DISEASE, CLINICAL-DIAGNOSIS, ROAD TEST, PERFORMANCE, DEMENTIA, DRIVERS, ACCURACY, CRITERIA, FITNESS, PEOPLE

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