Does smoking influence outcome after intravenous thrombolysis for acute ischaemic stroke?Aries, M. J. H., Uyttenboogaart, M., Koch, M. W., Langedijk, M., Vroomen, P. C., Luijckx, G. J. & De Keyser, J., Jul-2009, In : European Journal of Neurology. 16, 7, p. 819-822 4 p.
Research output: Contribution to journal › Article › Academic › peer-review
It remains uncertain whether current smoking influences outcome in patients with acute ischaemic stroke.
To evaluate the effect of current smoking in routinely tissue plasminogen activator (tPA)-treated stroke patients on the 3-month functional outcome and the occurrence of symptomatic intracerebral hemorrhage (ICH).
We analyzed data from a single stroke care unit registry of 345 consecutive patients with ischaemic stroke, treated with tPA. Logistic regression models were used to assess if smoking was independently associated with 3-months good outcome defined as a modified Rankin Scale score of
In the multivariable models, smoking was not associated with a good outcome or a decreased risk of symptomatic ICH.
Current smoking did not affect functional outcome at 3 months or the risk of symptomatic ICH in patients routinely treated with tPA for ischaemic stroke.
|Number of pages||4|
|Journal||European Journal of Neurology|
|Publication status||Published - Jul-2009|
- ischaemic stroke, outcome, smoking, symptomatic intracerebral hemorrhage, thrombolysis, tissue plasminogen activator, ACUTE MYOCARDIAL-INFARCTION, THERAPY, TRIAL, MORTALITY, PARADOX