Publication

Diversification of self-replicating molecules

Sadownik, J. W., Mattia, E., Nowak, P. & Otto, S., 2016, In : Nature Chemistry. 8, 3, p. 264-269 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Sadownik, J. W., Mattia, E., Nowak, P., & Otto, S. (2016). Diversification of self-replicating molecules. Nature Chemistry, 8(3), 264-269. https://doi.org/10.1038/nchem.2419

Author

Sadownik, Jan W. ; Mattia, Elio ; Nowak, Piotr ; Otto, Sijbren. / Diversification of self-replicating molecules. In: Nature Chemistry. 2016 ; Vol. 8, No. 3. pp. 264-269.

Harvard

Sadownik, JW, Mattia, E, Nowak, P & Otto, S 2016, 'Diversification of self-replicating molecules', Nature Chemistry, vol. 8, no. 3, pp. 264-269. https://doi.org/10.1038/nchem.2419

Standard

Diversification of self-replicating molecules. / Sadownik, Jan W.; Mattia, Elio; Nowak, Piotr; Otto, Sijbren.

In: Nature Chemistry, Vol. 8, No. 3, 2016, p. 264-269.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Sadownik JW, Mattia E, Nowak P, Otto S. Diversification of self-replicating molecules. Nature Chemistry. 2016;8(3):264-269. https://doi.org/10.1038/nchem.2419


BibTeX

@article{132b8a8828e24faaafeecc002adebb98,
title = "Diversification of self-replicating molecules",
abstract = "How new species emerge in nature is still incompletely understood and difficult to study directly. Self-replicating molecules provide a simple model that allows us to capture the fundamental processes that occur in species formation. We have been able to monitor in real time and at a molecular level the diversification of self-replicating molecules into two distinct sets that compete for two different building blocks ('food') and so capture an important aspect of the process by which species may arise. The results show that the second replicator set is a descendant of the first and that both sets are kinetic products that oppose the thermodynamic preference of the system. The sets occupy related but complementary food niches. As diversification into sets takes place on the timescale of weeks and can be investigated at the molecular level, this work opens up new opportunities for experimentally investigating the process through which species arise both in real time and with enhanced detail.",
author = "Sadownik, {Jan W.} and Elio Mattia and Piotr Nowak and Sijbren Otto",
year = "2016",
doi = "10.1038/nchem.2419",
language = "English",
volume = "8",
pages = "264--269",
journal = "Nature Chemistry",
issn = "1755-4330",
publisher = "Nature Publishing Group",
number = "3",

}

RIS

TY - JOUR

T1 - Diversification of self-replicating molecules

AU - Sadownik, Jan W.

AU - Mattia, Elio

AU - Nowak, Piotr

AU - Otto, Sijbren

PY - 2016

Y1 - 2016

N2 - How new species emerge in nature is still incompletely understood and difficult to study directly. Self-replicating molecules provide a simple model that allows us to capture the fundamental processes that occur in species formation. We have been able to monitor in real time and at a molecular level the diversification of self-replicating molecules into two distinct sets that compete for two different building blocks ('food') and so capture an important aspect of the process by which species may arise. The results show that the second replicator set is a descendant of the first and that both sets are kinetic products that oppose the thermodynamic preference of the system. The sets occupy related but complementary food niches. As diversification into sets takes place on the timescale of weeks and can be investigated at the molecular level, this work opens up new opportunities for experimentally investigating the process through which species arise both in real time and with enhanced detail.

AB - How new species emerge in nature is still incompletely understood and difficult to study directly. Self-replicating molecules provide a simple model that allows us to capture the fundamental processes that occur in species formation. We have been able to monitor in real time and at a molecular level the diversification of self-replicating molecules into two distinct sets that compete for two different building blocks ('food') and so capture an important aspect of the process by which species may arise. The results show that the second replicator set is a descendant of the first and that both sets are kinetic products that oppose the thermodynamic preference of the system. The sets occupy related but complementary food niches. As diversification into sets takes place on the timescale of weeks and can be investigated at the molecular level, this work opens up new opportunities for experimentally investigating the process through which species arise both in real time and with enhanced detail.

U2 - 10.1038/nchem.2419

DO - 10.1038/nchem.2419

M3 - Article

VL - 8

SP - 264

EP - 269

JO - Nature Chemistry

JF - Nature Chemistry

SN - 1755-4330

IS - 3

ER -

ID: 32895611