Publication

Diuretic response and renal function in heart failure

ter Maaten, J. M., 2016, [Groningen]: Rijksuniversiteit Groningen. 241 p.

Research output: ThesisThesis fully internal (DIV)

Copy link to clipboard

Documents

  • Title and contents

    Final publisher's version, 567 KB, PDF document

  • Chapter 1

    Final publisher's version, 537 KB, PDF document

  • Chapter 2

    Final publisher's version, 2.99 MB, PDF document

  • Chapter 3

    Final publisher's version, 764 KB, PDF document

  • Chapter 4

    Final publisher's version, 633 KB, PDF document

  • Chapter 5

    Final publisher's version, 652 KB, PDF document

  • Chapter 6

    Final publisher's version, 538 KB, PDF document

  • Chapter 7

    Final publisher's version, 747 KB, PDF document

  • Chapter 8

    Final publisher's version, 1.03 MB, PDF document

  • Chapter 9

    Final publisher's version, 681 KB, PDF document

  • Chapter 10

    Final publisher's version, 1.49 MB, PDF document

  • Chapter 11

    Final publisher's version, 569 KB, PDF document

  • Appendices

    Final publisher's version, 590 KB, PDF document

  • Complete thesis

    Final publisher's version, 5.59 MB, PDF document

  • Propositions

    Final publisher's version, 516 KB, PDF document

  • Jozine Magdalena ter Maaten
In patients with heart failure fluid overload is a frequently occurring problem, which is among others caused by an impaired function of the heart. This fluid overload may lead to severe dyspnea warranting an acute hospitalization. The first choice treatment of this fluid overload is administration of water pills. The effect of these pills is that excess water is lost with the urine. The research in this thesis showed that a great number of patients do not respond well to this treatment. A poor response is also associated with higher hospitalization and mortality rates and is therefore a great problem. One of the reasons why these patients do not respond well are renal adaptations. This causes an impaired response as these pills act on the kidney. Several biomarkers in the circulation can help in assessing both renal function and response to these water pills. Our research also showed that clincians can already assess response to treatment 24 hours after starting. Future research will have to show whether (additional) treatment with other medications will improve the response and hopefully also survival of these severely diseased patients.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
Supervisors/Advisors
Award date20-Jun-2016
Place of Publication[Groningen]
Publisher
Print ISBNs978-94-6169-884-1
Publication statusPublished - 2016

Download statistics

No data available

ID: 32723586