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Distinguishing Patients With a Coordination Disorder From Healthy Controls Using Local Features of Movement Trajectories During the Finger-to-Nose Test

Soancatl Aguilar, V., Martinez Manzanera, O., Sival, D. A., Maurits, N. M. & Roerdink, J. B. T. M., Jun-2019, In : IEEE Trans. Biomedical Engineering. 66, 6, p. 1714-1722 9 p.

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  • Distinguishing Patients with a Coordination Disorder from Healthy Controls using Local Features of Movement Trajectories during the Finger-to-nose Test

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DOI

Assessment of coordination disorders is valuable for monitoring progression of patients, distinguishing healthy and pathological conditions, and ultimately aiding in clinical decision making, thereby offering the possibility to improve medical care or rehabilitation. A common method to assess movement disorders is by using clinical rating scales. However, rating scales depend on the evaluation and interpretation of an observer, implying that subjective phenotypic assignment precedes the application of the scales. Objective and more accurate methods are under continuous development but gold standards are still scarce. Here, we show how a method we previously developed, originally aimed at assessing dynamic balance by a probabilistic generalized linear model, can be used to assess a broader range of functional movements. In this paper, the method is applied to distinguish patients with coordination disorders from healthy controls. We focused on movements recorded during the finger-to-nose task (FNT), which is commonly used to assess coordination disorders. We also compared clinical FNT scores and model scores. Our method achieved 84% classification accuracy in distinguishing patients and healthy participants, using only two features. Future work could entail testing the reliability of the method by using additional features and other clinical tests such as finger chasing, quiet standing, and/or usage of tracking devices such as depth cameras or force plates.

Original languageEnglish
Pages (from-to)1714-1722
Number of pages9
JournalIEEE Trans. Biomedical Engineering
Volume66
Issue number6
Early online date2018
Publication statusPublished - Jun-2019

    Keywords

  • Coordination disorders, classification, finger-to-nose test, generalized linear models, instantaneous speed and local curvature, ATAXIA, CLASSIFICATION, RELIABILITY, CHILDREN

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