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Disagreement of diameter and volume measurements for pulmonary nodule size estimation in CT lung cancer screening

Heuvelmans, M. A., Walter, J. E., Vliegenthart, R., van Ooijen, P. M. A., De Bock, G. H., de Koning, H. J. & Oudkerk, M., Aug-2018, In : Thorax. 73, 8, p. 779-781 3 p.

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  • Disagreement of diameter and volume measurements for pulmonary nodule size estimation in CT lung cancer screening

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DOI

We studied 2240 indeterminate solid nodules (volume 50-500 mm(3)) to determine the correlation of diameter and semi-automated volume measurements for pulmonary nodule size estimation. Intra-nodular diameter variation, defined as maximum minus minimum diameter through the nodule's center, varied by 2.8 mm (median, IQR: 2.2-3.7 mm), so above the 1.5 mm cutoff for nodule growth used in Lung CT Screening Reporting and Data System (Lung-RADS). Using mean or maximum axial diameter to assess nodule volume led to a substantial mean overestimation of nodule volume of 47.2% and 85.1%, respectively, compared to semi-automated volume. Thus, size of indeterminate nodules is poorly represented by diameter.

Original languageEnglish
Pages (from-to)779-781
Number of pages3
JournalThorax
Volume73
Issue number8
Early online date22-Oct-2017
Publication statusPublished - Aug-2018

    Keywords

  • Journal Article

ID: 49525096