Disagreement of diameter and volume measurements for pulmonary nodule size estimation in CT lung cancer screeningHeuvelmans, M. A., Walter, J. E., Vliegenthart, R., van Ooijen, P. M. A., De Bock, G. H., de Koning, H. J. & Oudkerk, M., Aug-2018, In : Thorax. 73, 8, p. 779-781 3 p.
Research output: Contribution to journal › Letter › Academic › peer-review
We studied 2240 indeterminate solid nodules (volume 50-500 mm(3)) to determine the correlation of diameter and semi-automated volume measurements for pulmonary nodule size estimation. Intra-nodular diameter variation, defined as maximum minus minimum diameter through the nodule's center, varied by 2.8 mm (median, IQR: 2.2-3.7 mm), so above the 1.5 mm cutoff for nodule growth used in Lung CT Screening Reporting and Data System (Lung-RADS). Using mean or maximum axial diameter to assess nodule volume led to a substantial mean overestimation of nodule volume of 47.2% and 85.1%, respectively, compared to semi-automated volume. Thus, size of indeterminate nodules is poorly represented by diameter.
|Number of pages||3|
|Early online date||22-Oct-2017|
|Publication status||Published - Aug-2018|
- Journal Article