Publication

Differences in the diagnostic value between fiberoptic and high definition laryngoscopy for the characterisation of pharyngeal and laryngeal lesions: A multi-observer paired analysis of videos

Scholman, C., Westra, J. M., Zwakenberg, M. A., Dikkers, F. G., Halmos, G. B., Wedman, J., Wachters, J. E., van der Laan, B. F. A. M. & Plaat, B. E. C., Jan-2020, In : Clinical Otolaryngology. 45, 1, p. 119-125 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Scholman, C., Westra, J. M., Zwakenberg, M. A., Dikkers, F. G., Halmos, G. B., Wedman, J., Wachters, J. E., van der Laan, B. F. A. M., & Plaat, B. E. C. (2020). Differences in the diagnostic value between fiberoptic and high definition laryngoscopy for the characterisation of pharyngeal and laryngeal lesions: A multi-observer paired analysis of videos. Clinical Otolaryngology, 45(1), 119-125. https://doi.org/10.1111/coa.13476

Author

Scholman, Constanze ; Westra, Jeroen M. ; Zwakenberg, Manon A. ; Dikkers, Frederik G. ; Halmos, Gyorgy B. ; Wedman, Jan ; Wachters, Jan E. ; van der Laan, Bernard F. A. M. ; Plaat, Boudewijn E. C. / Differences in the diagnostic value between fiberoptic and high definition laryngoscopy for the characterisation of pharyngeal and laryngeal lesions : A multi-observer paired analysis of videos. In: Clinical Otolaryngology. 2020 ; Vol. 45, No. 1. pp. 119-125.

Harvard

Scholman, C, Westra, JM, Zwakenberg, MA, Dikkers, FG, Halmos, GB, Wedman, J, Wachters, JE, van der Laan, BFAM & Plaat, BEC 2020, 'Differences in the diagnostic value between fiberoptic and high definition laryngoscopy for the characterisation of pharyngeal and laryngeal lesions: A multi-observer paired analysis of videos', Clinical Otolaryngology, vol. 45, no. 1, pp. 119-125. https://doi.org/10.1111/coa.13476

Standard

Differences in the diagnostic value between fiberoptic and high definition laryngoscopy for the characterisation of pharyngeal and laryngeal lesions : A multi-observer paired analysis of videos. / Scholman, Constanze; Westra, Jeroen M.; Zwakenberg, Manon A.; Dikkers, Frederik G.; Halmos, Gyorgy B.; Wedman, Jan; Wachters, Jan E.; van der Laan, Bernard F. A. M.; Plaat, Boudewijn E. C.

In: Clinical Otolaryngology, Vol. 45, No. 1, 01.2020, p. 119-125.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Scholman C, Westra JM, Zwakenberg MA, Dikkers FG, Halmos GB, Wedman J et al. Differences in the diagnostic value between fiberoptic and high definition laryngoscopy for the characterisation of pharyngeal and laryngeal lesions: A multi-observer paired analysis of videos. Clinical Otolaryngology. 2020 Jan;45(1):119-125. https://doi.org/10.1111/coa.13476


BibTeX

@article{4c480d3e010241fd883e4dab8eee77c3,
title = "Differences in the diagnostic value between fiberoptic and high definition laryngoscopy for the characterisation of pharyngeal and laryngeal lesions: A multi-observer paired analysis of videos",
abstract = "Objectives High definition laryngoscopy (HDL) could lead to better interpretation of the pharyngeal and laryngeal mucosa than regularly used fiberoptic laryngoscopy (FOL). The primary aim of this study is to quantify the diagnostic advantage of HDL over FOL in detecting mucosal anomalies in general, in differentiating malignant from benign lesions and in predicting specific histological entities. The secondary aim is to analyse image quality of both laryngoscopes. Design Retrospective paired analysis with multiple observers evaluating endoscopic videos simulating daily clinical practice. Setting A tertiary referral hospital. Participants In 36 patients, both FOL and HDL videos were obtained. Six observers were provided with additional clinical information, and 36 FOL and HDL videos were evaluated in a randomised order. Main outcome measures Sensitivity, specificity, positive and negative predictive value and diagnostic accuracy of observers using both flexible laryngoscopes were calculated for detection of mucosal lesions in general and uncovering malignant lesions. Sensitivities were calculated for prediction of specific histological entities. Image quality (scale 1-10) was assessed for both flexible laryngoscopes. Results HDL reached higher sensitivity compared to FOL for detection of mucosal abnormalities in general (96.0% vs 90.4%; P = .03), differentiating malignant from benign lesions (91.7% vs 79.8%; P = .03) and prediction of specific histological entities (59.7% vs 47.2%; P <.01). Image quality was judged better with HDL in comparison with FOL (mean: 8.4 vs 5.4, P <.01). Conclusions HDL is superior to FOL in detecting mucosal anomalies in general, malignancies and specific histological entities. Image quality is considered as superior using HDL compared to FOL.",
keywords = "laryngeal mucosa, laryngoscopy, larynx, mucous membrane, neoplasms, pharynx, sensitivity and specificity, CANCER, ACCURACY, SYSTEM, HEAD",
author = "Constanze Scholman and Westra, {Jeroen M.} and Zwakenberg, {Manon A.} and Dikkers, {Frederik G.} and Halmos, {Gyorgy B.} and Jan Wedman and Wachters, {Jan E.} and {van der Laan}, {Bernard F. A. M.} and Plaat, {Boudewijn E. C.}",
year = "2020",
month = jan,
doi = "10.1111/coa.13476",
language = "English",
volume = "45",
pages = "119--125",
journal = "Clinical Otolaryngology",
issn = "0307-7772",
publisher = "Wiley",
number = "1",

}

RIS

TY - JOUR

T1 - Differences in the diagnostic value between fiberoptic and high definition laryngoscopy for the characterisation of pharyngeal and laryngeal lesions

T2 - A multi-observer paired analysis of videos

AU - Scholman, Constanze

AU - Westra, Jeroen M.

AU - Zwakenberg, Manon A.

AU - Dikkers, Frederik G.

AU - Halmos, Gyorgy B.

AU - Wedman, Jan

AU - Wachters, Jan E.

AU - van der Laan, Bernard F. A. M.

AU - Plaat, Boudewijn E. C.

PY - 2020/1

Y1 - 2020/1

N2 - Objectives High definition laryngoscopy (HDL) could lead to better interpretation of the pharyngeal and laryngeal mucosa than regularly used fiberoptic laryngoscopy (FOL). The primary aim of this study is to quantify the diagnostic advantage of HDL over FOL in detecting mucosal anomalies in general, in differentiating malignant from benign lesions and in predicting specific histological entities. The secondary aim is to analyse image quality of both laryngoscopes. Design Retrospective paired analysis with multiple observers evaluating endoscopic videos simulating daily clinical practice. Setting A tertiary referral hospital. Participants In 36 patients, both FOL and HDL videos were obtained. Six observers were provided with additional clinical information, and 36 FOL and HDL videos were evaluated in a randomised order. Main outcome measures Sensitivity, specificity, positive and negative predictive value and diagnostic accuracy of observers using both flexible laryngoscopes were calculated for detection of mucosal lesions in general and uncovering malignant lesions. Sensitivities were calculated for prediction of specific histological entities. Image quality (scale 1-10) was assessed for both flexible laryngoscopes. Results HDL reached higher sensitivity compared to FOL for detection of mucosal abnormalities in general (96.0% vs 90.4%; P = .03), differentiating malignant from benign lesions (91.7% vs 79.8%; P = .03) and prediction of specific histological entities (59.7% vs 47.2%; P <.01). Image quality was judged better with HDL in comparison with FOL (mean: 8.4 vs 5.4, P <.01). Conclusions HDL is superior to FOL in detecting mucosal anomalies in general, malignancies and specific histological entities. Image quality is considered as superior using HDL compared to FOL.

AB - Objectives High definition laryngoscopy (HDL) could lead to better interpretation of the pharyngeal and laryngeal mucosa than regularly used fiberoptic laryngoscopy (FOL). The primary aim of this study is to quantify the diagnostic advantage of HDL over FOL in detecting mucosal anomalies in general, in differentiating malignant from benign lesions and in predicting specific histological entities. The secondary aim is to analyse image quality of both laryngoscopes. Design Retrospective paired analysis with multiple observers evaluating endoscopic videos simulating daily clinical practice. Setting A tertiary referral hospital. Participants In 36 patients, both FOL and HDL videos were obtained. Six observers were provided with additional clinical information, and 36 FOL and HDL videos were evaluated in a randomised order. Main outcome measures Sensitivity, specificity, positive and negative predictive value and diagnostic accuracy of observers using both flexible laryngoscopes were calculated for detection of mucosal lesions in general and uncovering malignant lesions. Sensitivities were calculated for prediction of specific histological entities. Image quality (scale 1-10) was assessed for both flexible laryngoscopes. Results HDL reached higher sensitivity compared to FOL for detection of mucosal abnormalities in general (96.0% vs 90.4%; P = .03), differentiating malignant from benign lesions (91.7% vs 79.8%; P = .03) and prediction of specific histological entities (59.7% vs 47.2%; P <.01). Image quality was judged better with HDL in comparison with FOL (mean: 8.4 vs 5.4, P <.01). Conclusions HDL is superior to FOL in detecting mucosal anomalies in general, malignancies and specific histological entities. Image quality is considered as superior using HDL compared to FOL.

KW - laryngeal mucosa

KW - laryngoscopy

KW - larynx

KW - mucous membrane

KW - neoplasms

KW - pharynx

KW - sensitivity and specificity

KW - CANCER

KW - ACCURACY

KW - SYSTEM

KW - HEAD

U2 - 10.1111/coa.13476

DO - 10.1111/coa.13476

M3 - Article

VL - 45

SP - 119

EP - 125

JO - Clinical Otolaryngology

JF - Clinical Otolaryngology

SN - 0307-7772

IS - 1

ER -

ID: 109244033