Publication

Diagnostic accuracy of arterial and venous renal Doppler assessment for acute kidney injury in critically ill patients: A prospective study

SICS Study Group, Wiersema, R., Kaufmann, T., van der Veen, H. N., de Haas, R. J., Franssen, C. F. M., Koeze, J., van der Horst, I. C. C. & Keus, F., Oct-2020, In : Journal of Critical Care. 59, p. 57-62 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

SICS Study Group, Wiersema, R., Kaufmann, T., van der Veen, H. N., de Haas, R. J., Franssen, C. F. M., ... Keus, F. (2020). Diagnostic accuracy of arterial and venous renal Doppler assessment for acute kidney injury in critically ill patients: A prospective study. Journal of Critical Care, 59, 57-62. https://doi.org/10.1016/j.jcrc.2020.05.012

Author

SICS Study Group ; Wiersema, Renske ; Kaufmann, Thomas ; van der Veen, Hilde N ; de Haas, Robbert J ; Franssen, Casper F M ; Koeze, Jacqueline ; van der Horst, Iwan C C ; Keus, Frederik. / Diagnostic accuracy of arterial and venous renal Doppler assessment for acute kidney injury in critically ill patients : A prospective study. In: Journal of Critical Care. 2020 ; Vol. 59. pp. 57-62.

Harvard

SICS Study Group, Wiersema, R, Kaufmann, T, van der Veen, HN, de Haas, RJ, Franssen, CFM, Koeze, J, van der Horst, ICC & Keus, F 2020, 'Diagnostic accuracy of arterial and venous renal Doppler assessment for acute kidney injury in critically ill patients: A prospective study', Journal of Critical Care, vol. 59, pp. 57-62. https://doi.org/10.1016/j.jcrc.2020.05.012

Standard

Diagnostic accuracy of arterial and venous renal Doppler assessment for acute kidney injury in critically ill patients : A prospective study. / SICS Study Group ; Wiersema, Renske; Kaufmann, Thomas; van der Veen, Hilde N; de Haas, Robbert J; Franssen, Casper F M; Koeze, Jacqueline; van der Horst, Iwan C C; Keus, Frederik.

In: Journal of Critical Care, Vol. 59, 10.2020, p. 57-62.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

SICS Study Group, Wiersema R, Kaufmann T, van der Veen HN, de Haas RJ, Franssen CFM et al. Diagnostic accuracy of arterial and venous renal Doppler assessment for acute kidney injury in critically ill patients: A prospective study. Journal of Critical Care. 2020 Oct;59:57-62. https://doi.org/10.1016/j.jcrc.2020.05.012


BibTeX

@article{1901c12f8d8141c0a5871ab12a70fe5a,
title = "Diagnostic accuracy of arterial and venous renal Doppler assessment for acute kidney injury in critically ill patients: A prospective study",
abstract = "BACKGROUND AND PURPOSE: Renal Resistive Index (RRI) and Venous Impedance Index (VII) might be of additional value for diagnosing Acute Kidney Injury (AKI). The purpose of this study was to assess the diagnostic accuracy of RRI and VII for AKI.MATERIALS AND METHODS: In the prospective Simple Intensive Care Studies-II (NCT03577405), we measured RRI and VII in acutely admitted adult intensive care patients within 24 h of admission. AKI was defined by the Kidney Disease Improving Global Outcome (KDIGO) criteria. The primary outcome was persistent AKI, defined as non-resolved AKI on day three. We tested specificity, sensitivity and diagnostic accuracy of both RRI and VII for persistent AKI.RESULTS: In total, 371 patients were included of whom 123 patients (33{\%}) had persistent AKI. RRI and VII did not differ between patients with and those without persistent AKI (p = .08 and p = .59). RRI had a moderate specificity (72{\%}, 95{\%}CI 66-78{\%}) and low sensitivity (32{\%}, 95{\%}CI 24-41{\%}) and VII had high sensitivity (93{\%}, 95{\%}CI 85-98{\%}) and low specificity (11{\%}, 95{\%}CI 6-16{\%}) for persistent AKI. Overall diagnostic accuracy of RRI and VII was moderate.CONCLUSIONS: In acutely admitted critically ill patients, measures of renal perfusion by renal ultrasound were not different between patients with and without AKI, and show limited diagnostic accuracy for AKI. Registered:NCT03577405.",
author = "{SICS Study Group} and Renske Wiersema and Thomas Kaufmann and {van der Veen}, {Hilde N} and {de Haas}, {Robbert J} and Franssen, {Casper F M} and Jacqueline Koeze and {van der Horst}, {Iwan C C} and Frederik Keus",
note = "Copyright {\circledC} 2020. Published by Elsevier Inc.",
year = "2020",
month = "10",
doi = "10.1016/j.jcrc.2020.05.012",
language = "English",
volume = "59",
pages = "57--62",
journal = "Journal of Critical Care",
issn = "0883-9441",
publisher = "W B SAUNDERS CO-ELSEVIER INC",

}

RIS

TY - JOUR

T1 - Diagnostic accuracy of arterial and venous renal Doppler assessment for acute kidney injury in critically ill patients

T2 - A prospective study

AU - SICS Study Group

AU - Wiersema, Renske

AU - Kaufmann, Thomas

AU - van der Veen, Hilde N

AU - de Haas, Robbert J

AU - Franssen, Casper F M

AU - Koeze, Jacqueline

AU - van der Horst, Iwan C C

AU - Keus, Frederik

N1 - Copyright © 2020. Published by Elsevier Inc.

PY - 2020/10

Y1 - 2020/10

N2 - BACKGROUND AND PURPOSE: Renal Resistive Index (RRI) and Venous Impedance Index (VII) might be of additional value for diagnosing Acute Kidney Injury (AKI). The purpose of this study was to assess the diagnostic accuracy of RRI and VII for AKI.MATERIALS AND METHODS: In the prospective Simple Intensive Care Studies-II (NCT03577405), we measured RRI and VII in acutely admitted adult intensive care patients within 24 h of admission. AKI was defined by the Kidney Disease Improving Global Outcome (KDIGO) criteria. The primary outcome was persistent AKI, defined as non-resolved AKI on day three. We tested specificity, sensitivity and diagnostic accuracy of both RRI and VII for persistent AKI.RESULTS: In total, 371 patients were included of whom 123 patients (33%) had persistent AKI. RRI and VII did not differ between patients with and those without persistent AKI (p = .08 and p = .59). RRI had a moderate specificity (72%, 95%CI 66-78%) and low sensitivity (32%, 95%CI 24-41%) and VII had high sensitivity (93%, 95%CI 85-98%) and low specificity (11%, 95%CI 6-16%) for persistent AKI. Overall diagnostic accuracy of RRI and VII was moderate.CONCLUSIONS: In acutely admitted critically ill patients, measures of renal perfusion by renal ultrasound were not different between patients with and without AKI, and show limited diagnostic accuracy for AKI. Registered:NCT03577405.

AB - BACKGROUND AND PURPOSE: Renal Resistive Index (RRI) and Venous Impedance Index (VII) might be of additional value for diagnosing Acute Kidney Injury (AKI). The purpose of this study was to assess the diagnostic accuracy of RRI and VII for AKI.MATERIALS AND METHODS: In the prospective Simple Intensive Care Studies-II (NCT03577405), we measured RRI and VII in acutely admitted adult intensive care patients within 24 h of admission. AKI was defined by the Kidney Disease Improving Global Outcome (KDIGO) criteria. The primary outcome was persistent AKI, defined as non-resolved AKI on day three. We tested specificity, sensitivity and diagnostic accuracy of both RRI and VII for persistent AKI.RESULTS: In total, 371 patients were included of whom 123 patients (33%) had persistent AKI. RRI and VII did not differ between patients with and those without persistent AKI (p = .08 and p = .59). RRI had a moderate specificity (72%, 95%CI 66-78%) and low sensitivity (32%, 95%CI 24-41%) and VII had high sensitivity (93%, 95%CI 85-98%) and low specificity (11%, 95%CI 6-16%) for persistent AKI. Overall diagnostic accuracy of RRI and VII was moderate.CONCLUSIONS: In acutely admitted critically ill patients, measures of renal perfusion by renal ultrasound were not different between patients with and without AKI, and show limited diagnostic accuracy for AKI. Registered:NCT03577405.

U2 - 10.1016/j.jcrc.2020.05.012

DO - 10.1016/j.jcrc.2020.05.012

M3 - Article

C2 - 32526633

VL - 59

SP - 57

EP - 62

JO - Journal of Critical Care

JF - Journal of Critical Care

SN - 0883-9441

ER -

ID: 127957193