Publication

Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire: comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the hospital Anxiety and Depression Scale (HADS)

Terluin, B., Brouwers, E., van Marwijk, H. W. J., Verhaak, P. & van der Horst, H., 23-Aug-2009, In : BMC Family Practice. 10, 58, 12 p., 58.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Terluin, B., Brouwers, E., van Marwijk, H. W. J., Verhaak, P., & van der Horst, H. (2009). Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire: comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the hospital Anxiety and Depression Scale (HADS). BMC Family Practice, 10(58), [58]. https://doi.org/10.1186/1471-2296-10-58

Author

Terluin, Berend ; Brouwers, Evelien ; van Marwijk, Harm W. J. ; Verhaak, Peter ; van der Horst, Henriette . / Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire : comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the hospital Anxiety and Depression Scale (HADS). In: BMC Family Practice. 2009 ; Vol. 10, No. 58.

Harvard

Terluin, B, Brouwers, E, van Marwijk, HWJ, Verhaak, P & van der Horst, H 2009, 'Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire: comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the hospital Anxiety and Depression Scale (HADS)', BMC Family Practice, vol. 10, no. 58, 58. https://doi.org/10.1186/1471-2296-10-58

Standard

Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire : comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the hospital Anxiety and Depression Scale (HADS). / Terluin, Berend; Brouwers, Evelien; van Marwijk, Harm W. J.; Verhaak, Peter; van der Horst, Henriette .

In: BMC Family Practice, Vol. 10, No. 58, 58, 23.08.2009.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Terluin B, Brouwers E, van Marwijk HWJ, Verhaak P, van der Horst H. Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire: comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the hospital Anxiety and Depression Scale (HADS). BMC Family Practice. 2009 Aug 23;10(58). 58. https://doi.org/10.1186/1471-2296-10-58


BibTeX

@article{b0b5628a49d54107b2f8cc7057509989,
title = "Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire: comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the hospital Anxiety and Depression Scale (HADS)",
abstract = "Background: Depressive and anxiety disorders often go unrecognized in distressed primary care patients, despite the overtlypsychosocial nature of their demand for help. This is especially problematic in more severe disorders needing specific treatment(e.g. antidepressant pharmacotherapy or specialized cognitive behavioural therapy). The use of a screening tool to detect (moresevere) depressive and anxiety disorders may be useful not to overlook such disorders. We examined the accuracy with whichthe Four-Dimensional Symptom Questionnaire (4DSQ) and the Hospital Anxiety and Depression Scale (HADS) are able todetect (more severe) depressive and anxiety disorders in distressed patients, and which cut-off points should be used.Methods: Seventy general practitioners (GPs) included 295 patients on sick leave due to psychological problems. They excludedpatients with recognized depressive or anxiety disorders. Patients completed the 4DSQ and HADS. Standardized diagnoses ofDSM-IV defined depressive and anxiety disorders were established with the Composite International Diagnostic Interview(CIDI). Receiver Operating Characteristic (ROC) analyses were performed to obtain sensitivity and specificity values for a rangeof scores, and area under the curve (AUC) values as a measure of diagnostic accuracy.Results: With respect to the detection of any depressive or anxiety disorder (180 patients, 61%), the 4DSQ and HADS scalesyielded comparable results with AUC values between 0.745 and 0.815. Also with respect to the detection of moderate or severedepressive disorder, the 4DSQ and HADS depression scales performed comparably (AUC 0.780 and 0.739, p 0.165). Withrespect to the detection of panic disorder, agoraphobia and social phobia, the 4DSQ anxiety scale performed significantly betterthan the HADS anxiety scale (AUC 0.852 versus 0.757, p 0.001). The recommended cut-off points of both HADS scalesappeared to be too low while those of the 4DSQ anxiety scale appeared to be too high.Conclusion: In general practice patients on sick leave because of psychological problems, the 4DSQ and the HADS are equallyable to detect depressive and anxiety disorders. However, for the detection of cases severe enough to warrant specifictreatment, the 4DSQ may have some advantages over the HADS, specifically for the detection of panic disorder, agoraphobiaand social phobia.",
author = "Berend Terluin and Evelien Brouwers and {van Marwijk}, {Harm W. J.} and Peter Verhaak and {van der Horst}, Henriette",
year = "2009",
month = aug,
day = "23",
doi = "10.1186/1471-2296-10-58",
language = "English",
volume = "10",
journal = "BMC Family Practice",
issn = "1471-2296",
publisher = "BioMed Central Ltd.",
number = "58",

}

RIS

TY - JOUR

T1 - Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire

T2 - comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the hospital Anxiety and Depression Scale (HADS)

AU - Terluin, Berend

AU - Brouwers, Evelien

AU - van Marwijk, Harm W. J.

AU - Verhaak, Peter

AU - van der Horst, Henriette

PY - 2009/8/23

Y1 - 2009/8/23

N2 - Background: Depressive and anxiety disorders often go unrecognized in distressed primary care patients, despite the overtlypsychosocial nature of their demand for help. This is especially problematic in more severe disorders needing specific treatment(e.g. antidepressant pharmacotherapy or specialized cognitive behavioural therapy). The use of a screening tool to detect (moresevere) depressive and anxiety disorders may be useful not to overlook such disorders. We examined the accuracy with whichthe Four-Dimensional Symptom Questionnaire (4DSQ) and the Hospital Anxiety and Depression Scale (HADS) are able todetect (more severe) depressive and anxiety disorders in distressed patients, and which cut-off points should be used.Methods: Seventy general practitioners (GPs) included 295 patients on sick leave due to psychological problems. They excludedpatients with recognized depressive or anxiety disorders. Patients completed the 4DSQ and HADS. Standardized diagnoses ofDSM-IV defined depressive and anxiety disorders were established with the Composite International Diagnostic Interview(CIDI). Receiver Operating Characteristic (ROC) analyses were performed to obtain sensitivity and specificity values for a rangeof scores, and area under the curve (AUC) values as a measure of diagnostic accuracy.Results: With respect to the detection of any depressive or anxiety disorder (180 patients, 61%), the 4DSQ and HADS scalesyielded comparable results with AUC values between 0.745 and 0.815. Also with respect to the detection of moderate or severedepressive disorder, the 4DSQ and HADS depression scales performed comparably (AUC 0.780 and 0.739, p 0.165). Withrespect to the detection of panic disorder, agoraphobia and social phobia, the 4DSQ anxiety scale performed significantly betterthan the HADS anxiety scale (AUC 0.852 versus 0.757, p 0.001). The recommended cut-off points of both HADS scalesappeared to be too low while those of the 4DSQ anxiety scale appeared to be too high.Conclusion: In general practice patients on sick leave because of psychological problems, the 4DSQ and the HADS are equallyable to detect depressive and anxiety disorders. However, for the detection of cases severe enough to warrant specifictreatment, the 4DSQ may have some advantages over the HADS, specifically for the detection of panic disorder, agoraphobiaand social phobia.

AB - Background: Depressive and anxiety disorders often go unrecognized in distressed primary care patients, despite the overtlypsychosocial nature of their demand for help. This is especially problematic in more severe disorders needing specific treatment(e.g. antidepressant pharmacotherapy or specialized cognitive behavioural therapy). The use of a screening tool to detect (moresevere) depressive and anxiety disorders may be useful not to overlook such disorders. We examined the accuracy with whichthe Four-Dimensional Symptom Questionnaire (4DSQ) and the Hospital Anxiety and Depression Scale (HADS) are able todetect (more severe) depressive and anxiety disorders in distressed patients, and which cut-off points should be used.Methods: Seventy general practitioners (GPs) included 295 patients on sick leave due to psychological problems. They excludedpatients with recognized depressive or anxiety disorders. Patients completed the 4DSQ and HADS. Standardized diagnoses ofDSM-IV defined depressive and anxiety disorders were established with the Composite International Diagnostic Interview(CIDI). Receiver Operating Characteristic (ROC) analyses were performed to obtain sensitivity and specificity values for a rangeof scores, and area under the curve (AUC) values as a measure of diagnostic accuracy.Results: With respect to the detection of any depressive or anxiety disorder (180 patients, 61%), the 4DSQ and HADS scalesyielded comparable results with AUC values between 0.745 and 0.815. Also with respect to the detection of moderate or severedepressive disorder, the 4DSQ and HADS depression scales performed comparably (AUC 0.780 and 0.739, p 0.165). Withrespect to the detection of panic disorder, agoraphobia and social phobia, the 4DSQ anxiety scale performed significantly betterthan the HADS anxiety scale (AUC 0.852 versus 0.757, p 0.001). The recommended cut-off points of both HADS scalesappeared to be too low while those of the 4DSQ anxiety scale appeared to be too high.Conclusion: In general practice patients on sick leave because of psychological problems, the 4DSQ and the HADS are equallyable to detect depressive and anxiety disorders. However, for the detection of cases severe enough to warrant specifictreatment, the 4DSQ may have some advantages over the HADS, specifically for the detection of panic disorder, agoraphobiaand social phobia.

U2 - 10.1186/1471-2296-10-58

DO - 10.1186/1471-2296-10-58

M3 - Article

VL - 10

JO - BMC Family Practice

JF - BMC Family Practice

SN - 1471-2296

IS - 58

M1 - 58

ER -

ID: 14842512