Publication

Depression and cardiac mortality - Results from a community-based longitudinal study

Penninx, BWJH., Beekman, ATF., Honig, A., Deeg, DJH., Schoevers, RA., van Eijk, JTM. & van Tilburg, W., Mar-2001, In : Archives of General Psychiatry. 58, 3, p. 221-227 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Penninx, BWJH., Beekman, ATF., Honig, A., Deeg, DJH., Schoevers, RA., van Eijk, JTM., & van Tilburg, W. (2001). Depression and cardiac mortality - Results from a community-based longitudinal study. Archives of General Psychiatry, 58(3), 221-227.

Author

Penninx, BWJH ; Beekman, ATF ; Honig, A ; Deeg, DJH ; Schoevers, RA ; van Eijk, JTM ; van Tilburg, W. / Depression and cardiac mortality - Results from a community-based longitudinal study. In: Archives of General Psychiatry. 2001 ; Vol. 58, No. 3. pp. 221-227.

Harvard

Penninx, BWJH, Beekman, ATF, Honig, A, Deeg, DJH, Schoevers, RA, van Eijk, JTM & van Tilburg, W 2001, 'Depression and cardiac mortality - Results from a community-based longitudinal study', Archives of General Psychiatry, vol. 58, no. 3, pp. 221-227.

Standard

Depression and cardiac mortality - Results from a community-based longitudinal study. / Penninx, BWJH; Beekman, ATF; Honig, A; Deeg, DJH; Schoevers, RA; van Eijk, JTM; van Tilburg, W.

In: Archives of General Psychiatry, Vol. 58, No. 3, 03.2001, p. 221-227.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Penninx BWJH, Beekman ATF, Honig A, Deeg DJH, Schoevers RA, van Eijk JTM et al. Depression and cardiac mortality - Results from a community-based longitudinal study. Archives of General Psychiatry. 2001 Mar;58(3):221-227.


BibTeX

@article{92f622e8c8be429b94e14e47d65cabc1,
title = "Depression and cardiac mortality - Results from a community-based longitudinal study",
abstract = "Background: Depression may be a potential risk factor for subsequent cardiac death. The impact of depression on cardiac mortality has been suggested to depend on cardiac disease status, and to be stronger among cardiac patients. This study examined and compared the effect of depression on cardiac mortality in community-dwelling persons with and without cardiac disease.Methods: A cohort of 2847 men and women aged 55 to 85 years was evaluated for 4 years. Major depression was defined according to psychiatric DSM-III criteria. Minor depression was defined by Center for Epidemiologic Studies-Depression Scale scores of 16 or higher. Effects of minor and major depression on cardiac mortality were examined separately in 450 subjects with a diagnosis of cardiac disease and in 2397 subjects without cardiac disease after adjusting for demographics, smoking, alcohol use, blood pressure, body mass index, and comorbidity.Results: Compared with nondepressed cardiac patients, the relative risk of subsequent cardiac mortality was 1.6 (95{\%} confidence interval ICI], 1.0-2.7) for cardiac patients with minor depression and 3.0 (95{\%} CI, 1.1-7.8) for cardiac patients with major depression, after adjustment for confounding variables. Among subjects without cardiac disease at baseline, similar increased cardiac mortality risks were found for minor depression (1.5 [95{\%} CI, 0.9-2.61) and major depression (3.9 [95{\%} CI, 1.4-10.9]).Conclusion: Depression increases the risk for cardiac mortality in subjects with and without cardiac disease at baseline. The excess cardiac mortality risk was more than twice as high for major depression as for minor depression.",
keywords = "ACUTE MYOCARDIAL-INFARCTION, CORONARY-ARTERY DISEASE, ISCHEMIC-HEART-DISEASE, CARDIOVASCULAR EVENTS, MAJOR DEPRESSION, OLDER PERSONS, LATER LIFE, RISK, SYMPTOMS, NETHERLANDS",
author = "BWJH Penninx and ATF Beekman and A Honig and DJH Deeg and RA Schoevers and {van Eijk}, JTM and {van Tilburg}, W",
year = "2001",
month = "3",
language = "English",
volume = "58",
pages = "221--227",
journal = "Archives of General Psychiatry",
issn = "0003-990X",
number = "3",

}

RIS

TY - JOUR

T1 - Depression and cardiac mortality - Results from a community-based longitudinal study

AU - Penninx, BWJH

AU - Beekman, ATF

AU - Honig, A

AU - Deeg, DJH

AU - Schoevers, RA

AU - van Eijk, JTM

AU - van Tilburg, W

PY - 2001/3

Y1 - 2001/3

N2 - Background: Depression may be a potential risk factor for subsequent cardiac death. The impact of depression on cardiac mortality has been suggested to depend on cardiac disease status, and to be stronger among cardiac patients. This study examined and compared the effect of depression on cardiac mortality in community-dwelling persons with and without cardiac disease.Methods: A cohort of 2847 men and women aged 55 to 85 years was evaluated for 4 years. Major depression was defined according to psychiatric DSM-III criteria. Minor depression was defined by Center for Epidemiologic Studies-Depression Scale scores of 16 or higher. Effects of minor and major depression on cardiac mortality were examined separately in 450 subjects with a diagnosis of cardiac disease and in 2397 subjects without cardiac disease after adjusting for demographics, smoking, alcohol use, blood pressure, body mass index, and comorbidity.Results: Compared with nondepressed cardiac patients, the relative risk of subsequent cardiac mortality was 1.6 (95% confidence interval ICI], 1.0-2.7) for cardiac patients with minor depression and 3.0 (95% CI, 1.1-7.8) for cardiac patients with major depression, after adjustment for confounding variables. Among subjects without cardiac disease at baseline, similar increased cardiac mortality risks were found for minor depression (1.5 [95% CI, 0.9-2.61) and major depression (3.9 [95% CI, 1.4-10.9]).Conclusion: Depression increases the risk for cardiac mortality in subjects with and without cardiac disease at baseline. The excess cardiac mortality risk was more than twice as high for major depression as for minor depression.

AB - Background: Depression may be a potential risk factor for subsequent cardiac death. The impact of depression on cardiac mortality has been suggested to depend on cardiac disease status, and to be stronger among cardiac patients. This study examined and compared the effect of depression on cardiac mortality in community-dwelling persons with and without cardiac disease.Methods: A cohort of 2847 men and women aged 55 to 85 years was evaluated for 4 years. Major depression was defined according to psychiatric DSM-III criteria. Minor depression was defined by Center for Epidemiologic Studies-Depression Scale scores of 16 or higher. Effects of minor and major depression on cardiac mortality were examined separately in 450 subjects with a diagnosis of cardiac disease and in 2397 subjects without cardiac disease after adjusting for demographics, smoking, alcohol use, blood pressure, body mass index, and comorbidity.Results: Compared with nondepressed cardiac patients, the relative risk of subsequent cardiac mortality was 1.6 (95% confidence interval ICI], 1.0-2.7) for cardiac patients with minor depression and 3.0 (95% CI, 1.1-7.8) for cardiac patients with major depression, after adjustment for confounding variables. Among subjects without cardiac disease at baseline, similar increased cardiac mortality risks were found for minor depression (1.5 [95% CI, 0.9-2.61) and major depression (3.9 [95% CI, 1.4-10.9]).Conclusion: Depression increases the risk for cardiac mortality in subjects with and without cardiac disease at baseline. The excess cardiac mortality risk was more than twice as high for major depression as for minor depression.

KW - ACUTE MYOCARDIAL-INFARCTION

KW - CORONARY-ARTERY DISEASE

KW - ISCHEMIC-HEART-DISEASE

KW - CARDIOVASCULAR EVENTS

KW - MAJOR DEPRESSION

KW - OLDER PERSONS

KW - LATER LIFE

KW - RISK

KW - SYMPTOMS

KW - NETHERLANDS

M3 - Article

VL - 58

SP - 221

EP - 227

JO - Archives of General Psychiatry

T2 - Archives of General Psychiatry

JF - Archives of General Psychiatry

SN - 0003-990X

IS - 3

ER -

ID: 24763013