Publication

Definition, discrimination, diagnosis and treatment of central breathing disturbances during sleep

Randerath, W., Verbraecken, J., Andreas, S., Arzt, M., Bloch, K. E., Brack, T., Buyse, B., De Backer, W., Eckert, D. J., Grote, L., Hagmeyer, L., Hedner, J., Jennum, P., La Rovere, M. T., Miltz, C., McNicholas, W. T., Montserrat, J., Naughton, M., Pepin, J-L., Pevernagie, D., Sanner, B., Testelmans, D., Tonia, T., Vrijsen, B., Wijkstra, P. & Levy, P., 2017, In : European Respiratory Journal. 49, 1, 28 p.

Research output: Contribution to journalArticleAcademicpeer-review

Copy link to clipboard

Documents

  • Definition, discrimination, diagnosis and treatment of central breathing disturbances during sleep

    Final publisher's version, 539 KB, PDF document

DOI

  • Winfried Randerath
  • Johan Verbraecken
  • Stefan Andreas
  • Michael Arzt
  • Konrad E Bloch
  • Thomas Brack
  • Bertien Buyse
  • Wilfried De Backer
  • Danny Joel Eckert
  • Ludger Grote
  • Lars Hagmeyer
  • Jan Hedner
  • Poul Jennum
  • Maria Teresa La Rovere
  • Carla Miltz
  • Walter T McNicholas
  • Josep Montserrat
  • Matthew Naughton
  • Jean-Louis Pepin
  • Dirk Pevernagie
  • Bernd Sanner
  • Dries Testelmans
  • Thomy Tonia
  • Bart Vrijsen
  • Peter Wijkstra
  • Patrick Levy

The complexity of central breathing disturbances during sleep has become increasingly obvious. They present as central sleep apnoeas (CSAs) and hypopnoeas, periodic breathing with apnoeas, or irregular breathing in patients with cardiovascular, other internal or neurological disorders, and can emerge under positive airway pressure treatment or opioid use, or at high altitude. As yet, there is insufficient knowledge on the clinical features, pathophysiological background and consecutive algorithms for stepped-care treatment. Most recently, it has been discussed intensively if CSA in heart failure is a "marker" of disease severity or a "mediator" of disease progression, and if and which type of positive airway pressure therapy is indicated. In addition, disturbances of respiratory drive or the translation of central impulses may result in hypoventilation, associated with cerebral or neuromuscular diseases, or severe diseases of lung or thorax. These statements report the results of an European Respiratory Society Task Force addressing actual diagnostic and therapeutic standards. The statements are based on a systematic review of the literature and a systematic two-step decision process. Although the Task Force does not make recommendations, it describes its current practice of treatment of CSA in heart failure and hypoventilation.

Original languageEnglish
Number of pages28
JournalEuropean Respiratory Journal
Volume49
Issue number1
Early online date5-Dec-2016
Publication statusPublished - 2017

    Keywords

  • POSITIVE AIRWAY PRESSURE, OBESITY-HYPOVENTILATION SYNDROME, CHEYNE-STOKES RESPIRATION, CHRONIC HEART-FAILURE, AMYOTROPHIC-LATERAL-SCLEROSIS, RANDOMIZED CONTROLLED-TRIAL, ADAPTIVE SERVO-VENTILATION, DUCHENNE MUSCULAR-DYSTROPHY, INTERSTITIAL LUNG-DISEASE, QUALITY-OF-LIFE

View graph of relations

ID: 38005875