Publication

CYTOGENETIC STUDY OF A NODULAR HYPERPLASIA OF THE THYROID AFTER IRRADIATION FOR HODGKINS-DISEASE

VANDENBERG, E., VANDOORMAAL, JJ., OOSTERHUIS, JW., DEJONG, B., BUIST, J., VOS, AM., VERMEIJ, A. & Dam, A., May-1991, In : Cancer Genetics and Cytogenetics. 53, 1, p. 15-21 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

We describe cytogenetics of a case of nodular hyperplasia of the thyroid with papillary microcarcinoma following radiotherapy for Hodgkin's disease. The chromosomal pattern found was very heterogeneous with a clonal abnormality of chromosome 10, among others. Together with some recent data from the literature, this finding may point to an important role of chromosome 10 abnormalities in the pathogenesis of benign and malignant thyroid neoplasms.

Original languageEnglish
Pages (from-to)15-21
Number of pages7
JournalCancer Genetics and Cytogenetics
Volume53
Issue number1
Publication statusPublished - May-1991

    Keywords

  • ENDOCRINE NEOPLASIA TYPE-2A, HUMAN CHROMOSOME-3, SOLID TUMORS, CARCINOMA, CANCER, SUSCEPTIBILITY, PREDISPOSITION, INSTABILITY, ADENOMAS, ONCOGENE

ID: 6288423