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Coping style predicts the (in)sensitivity for developing hyperinsulinemia on a high fat diet in rats

Boersma, G. J., Benthem, L., van Dijk, G., Steimer, T. J. & Scheurink, A. J. W., 16-Jun-2010, In : Physiology & Behavior. 100, 4, p. 401-407 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

APA

Boersma, G. J., Benthem, L., van Dijk, G., Steimer, T. J., & Scheurink, A. J. W. (2010). Coping style predicts the (in)sensitivity for developing hyperinsulinemia on a high fat diet in rats. Physiology & Behavior, 100(4), 401-407. https://doi.org/10.1016/j.physbeh.2010.04.007

Author

Boersma, Gretha J. ; Benthem, Lambertus ; van Dijk, Gertjan ; Steimer, Thierry J. ; Scheurink, Anton J. W. / Coping style predicts the (in)sensitivity for developing hyperinsulinemia on a high fat diet in rats. In: Physiology & Behavior. 2010 ; Vol. 100, No. 4. pp. 401-407.

Harvard

Boersma, GJ, Benthem, L, van Dijk, G, Steimer, TJ & Scheurink, AJW 2010, 'Coping style predicts the (in)sensitivity for developing hyperinsulinemia on a high fat diet in rats', Physiology & Behavior, vol. 100, no. 4, pp. 401-407. https://doi.org/10.1016/j.physbeh.2010.04.007

Standard

Coping style predicts the (in)sensitivity for developing hyperinsulinemia on a high fat diet in rats. / Boersma, Gretha J.; Benthem, Lambertus; van Dijk, Gertjan; Steimer, Thierry J.; Scheurink, Anton J. W.

In: Physiology & Behavior, Vol. 100, No. 4, 16.06.2010, p. 401-407.

Research output: Contribution to journal › Article › Academic › peer-review

Vancouver

Boersma GJ, Benthem L, van Dijk G, Steimer TJ, Scheurink AJW. Coping style predicts the (in)sensitivity for developing hyperinsulinemia on a high fat diet in rats. Physiology & Behavior. 2010 Jun 16;100(4):401-407. https://doi.org/10.1016/j.physbeh.2010.04.007

BibTeX

@article{b75f59ccd9ae4a1683453fa5e0c63ebc,
title = "Coping style predicts the (in)sensitivity for developing hyperinsulinemia on a high fat diet in rats",
abstract = "The aim of this study was to explore interactions between coping style and diet as risk factors for developing insulin resistance in rats. We hypothesized that rats characterized by a passive coping strategy are more susceptible for developing insulin resistance and visceral obesity than proactively coping rats, particularly on a high (45%) fat diet. This hypothesis was tested by comparing 1) insulin and glucose responses to an intravenous glucose tolerance test (IVGTT), and 2) body fat distribution, in two rat models for passive and proactive coping styles. We found that the most extremely passive rats are characterized by elevated insulin levels during a IVGTT, even on chow. Moderately passive rats display normal insulin responses under chow conditions, but develop insulin resistance on a high fat diet. Proactive rats are remarkably resistant to insulin resistance and visceral obesity, even when overfeeding on a high fat diet. Carcass analysis revealed that passive rats are characterized by increased epididymal fat deposition, which is in line with the observed differences in insulin resistance. We conclude that a passive personality is prone to develop insulin resistance and visceral obesity on a palatable fat diet and a proactive personality might be protected against the development of diet-induced insulin resistance. (C) 2010 Elsevier Inc. All rights reserved.",
keywords = "Insulin, Glucose, Personality, Visceral obesity, ROMAN HIGH-AVOIDANCE, MIDDLE-AGED MEN, INSULIN-RESISTANCE, METABOLIC SYNDROME, GLUCOSE, STRESS, BLOOD, GLUCOCORTICOIDS, INFUSION, BEHAVIOR",
author = "Boersma, {Gretha J.} and Lambertus Benthem and {van Dijk}, Gertjan and Steimer, {Thierry J.} and Scheurink, {Anton J. W.}",
year = "2010",
month = jun,
day = "16",
doi = "10.1016/j.physbeh.2010.04.007",
language = "English",
volume = "100",
pages = "401--407",
journal = "Physiology & Behavior",
issn = "0031-9384",
publisher = "PERGAMON-ELSEVIER SCIENCE LTD",
number = "4",

}

RIS

TY - JOUR

T1 - Coping style predicts the (in)sensitivity for developing hyperinsulinemia on a high fat diet in rats

AU - Boersma, Gretha J.

AU - Benthem, Lambertus

AU - van Dijk, Gertjan

AU - Steimer, Thierry J.

AU - Scheurink, Anton J. W.

PY - 2010/6/16

Y1 - 2010/6/16

N2 - The aim of this study was to explore interactions between coping style and diet as risk factors for developing insulin resistance in rats. We hypothesized that rats characterized by a passive coping strategy are more susceptible for developing insulin resistance and visceral obesity than proactively coping rats, particularly on a high (45%) fat diet. This hypothesis was tested by comparing 1) insulin and glucose responses to an intravenous glucose tolerance test (IVGTT), and 2) body fat distribution, in two rat models for passive and proactive coping styles. We found that the most extremely passive rats are characterized by elevated insulin levels during a IVGTT, even on chow. Moderately passive rats display normal insulin responses under chow conditions, but develop insulin resistance on a high fat diet. Proactive rats are remarkably resistant to insulin resistance and visceral obesity, even when overfeeding on a high fat diet. Carcass analysis revealed that passive rats are characterized by increased epididymal fat deposition, which is in line with the observed differences in insulin resistance. We conclude that a passive personality is prone to develop insulin resistance and visceral obesity on a palatable fat diet and a proactive personality might be protected against the development of diet-induced insulin resistance. (C) 2010 Elsevier Inc. All rights reserved.

AB - The aim of this study was to explore interactions between coping style and diet as risk factors for developing insulin resistance in rats. We hypothesized that rats characterized by a passive coping strategy are more susceptible for developing insulin resistance and visceral obesity than proactively coping rats, particularly on a high (45%) fat diet. This hypothesis was tested by comparing 1) insulin and glucose responses to an intravenous glucose tolerance test (IVGTT), and 2) body fat distribution, in two rat models for passive and proactive coping styles. We found that the most extremely passive rats are characterized by elevated insulin levels during a IVGTT, even on chow. Moderately passive rats display normal insulin responses under chow conditions, but develop insulin resistance on a high fat diet. Proactive rats are remarkably resistant to insulin resistance and visceral obesity, even when overfeeding on a high fat diet. Carcass analysis revealed that passive rats are characterized by increased epididymal fat deposition, which is in line with the observed differences in insulin resistance. We conclude that a passive personality is prone to develop insulin resistance and visceral obesity on a palatable fat diet and a proactive personality might be protected against the development of diet-induced insulin resistance. (C) 2010 Elsevier Inc. All rights reserved.

KW - Insulin

KW - Glucose

KW - Personality

KW - Visceral obesity

KW - ROMAN HIGH-AVOIDANCE

KW - MIDDLE-AGED MEN

KW - INSULIN-RESISTANCE

KW - METABOLIC SYNDROME

KW - GLUCOSE

KW - STRESS

KW - BLOOD

KW - GLUCOCORTICOIDS

KW - INFUSION

KW - BEHAVIOR

U2 - 10.1016/j.physbeh.2010.04.007

DO - 10.1016/j.physbeh.2010.04.007

M3 - Article

VL - 100

SP - 401

EP - 407

JO - Physiology & Behavior

JF - Physiology & Behavior

SN - 0031-9384

IS - 4

ER -

ID: 5108505

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