Publication

Conceptual design of a large pixelated CZT detector with four-hole collimator matched pixel detector for SPECT imaging: a Monte Carlo simulation study

Boutaghane, N., Bouzid, B. & Zaidi, H., Feb-2019, In : Journal of Instrumentation. 14, 16 p., 02026.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Boutaghane, N., Bouzid, B., & Zaidi, H. (2019). Conceptual design of a large pixelated CZT detector with four-hole collimator matched pixel detector for SPECT imaging: a Monte Carlo simulation study. Journal of Instrumentation, 14, [02026]. https://doi.org/10.1088/1748-0221/14/02/P02026

Author

Boutaghane, N. ; Bouzid, B. ; Zaidi, H. / Conceptual design of a large pixelated CZT detector with four-hole collimator matched pixel detector for SPECT imaging : a Monte Carlo simulation study. In: Journal of Instrumentation. 2019 ; Vol. 14.

Harvard

Boutaghane, N, Bouzid, B & Zaidi, H 2019, 'Conceptual design of a large pixelated CZT detector with four-hole collimator matched pixel detector for SPECT imaging: a Monte Carlo simulation study', Journal of Instrumentation, vol. 14, 02026. https://doi.org/10.1088/1748-0221/14/02/P02026

Standard

Conceptual design of a large pixelated CZT detector with four-hole collimator matched pixel detector for SPECT imaging : a Monte Carlo simulation study. / Boutaghane, N.; Bouzid, B.; Zaidi, H.

In: Journal of Instrumentation, Vol. 14, 02026, 02.2019.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Boutaghane N, Bouzid B, Zaidi H. Conceptual design of a large pixelated CZT detector with four-hole collimator matched pixel detector for SPECT imaging: a Monte Carlo simulation study. Journal of Instrumentation. 2019 Feb;14. 02026. https://doi.org/10.1088/1748-0221/14/02/P02026


BibTeX

@article{ae35d02190d6480892b17c81219c2e6e,
title = "Conceptual design of a large pixelated CZT detector with four-hole collimator matched pixel detector for SPECT imaging: a Monte Carlo simulation study",
abstract = "Significant progress has been achieved in the design of pixelated CZT detectors dedicated to cardiac and breast SPECT imaging. However, their detector geometry and associated collimators' design have limited their clinical use. The aim of this work is to determine the best combination between a large pixelated CZT detector and parallel-hole collimator that can provide high spatial resolution at low injected activity with low-energy radiotracers. Our proposed combination resulted in the design of a novel four-hole matched pixel detector (4-HMPD) configuration. Our novel 4-HMPD design based on large pixelated CZT detector was firstly compared to the standard one-hole matched pixel detector (1-HMPD) configuration using Monte Carlo simulation. We have also predicted the influence of pixel size, interpixel gap and source-to-collimator distance on the basis of resulting spatial resolution, sensitivity and crosstalk events fraction for three collimator hole lengths for Tc-99m (140 keV). Thereafter, we used the same detector and collimator settings of the 1-HMPD configuration as constructed with the D-SPECT camera module (Redlen Technologies, BC, Canada) for our 4-HMPD design to compare the performance of the two configurations. Our preliminary results showed that a large pixel size, a small interpixel gap and a small collimator hole length increased significantly the sensitivity at the detriment of spatial resolution. The performance comparison between the 4-HMPD and the 1-HMPD configurations demonstrated an improved reconstructed spatial resolution (by a factor two), higher contrast with the large sphere of the modified Jaszczak phantom (from 63.1{\%} to 39.1{\%}), clear appearance of cold spheres (> 14 mm diameter) and the cold cylinders (> 11.1 mm diameter). The crosstalk events fraction varied from 8.5{\%} to 12.8{\%}. Our novel detector/collimator combination allows less electronic readout complexity, less crosstalk events between pixels and twofold increase in septal thickness resulting in low septal penetration compared to the classical 1-HMPD configuration. It also showed the highest enhancement in terms of spatial resolution even in cases of low sensitivity with less injected activity, and outperformed the performance of existing conventional NaI (TI) crystal-based systems.",
keywords = "SPECT, CZT detector, parallel-hole collimator, Monte Carlo, crosstalk, SPATIAL-RESOLUTION, COMPENSATION, PERFORMANCE, CAMERAS, SYSTEM",
author = "N. Boutaghane and B. Bouzid and H. Zaidi",
year = "2019",
month = "2",
doi = "10.1088/1748-0221/14/02/P02026",
language = "English",
volume = "14",
journal = "Journal of Instrumentation",
issn = "1748-0221",
publisher = "IOP PUBLISHING LTD",

}

RIS

TY - JOUR

T1 - Conceptual design of a large pixelated CZT detector with four-hole collimator matched pixel detector for SPECT imaging

T2 - a Monte Carlo simulation study

AU - Boutaghane, N.

AU - Bouzid, B.

AU - Zaidi, H.

PY - 2019/2

Y1 - 2019/2

N2 - Significant progress has been achieved in the design of pixelated CZT detectors dedicated to cardiac and breast SPECT imaging. However, their detector geometry and associated collimators' design have limited their clinical use. The aim of this work is to determine the best combination between a large pixelated CZT detector and parallel-hole collimator that can provide high spatial resolution at low injected activity with low-energy radiotracers. Our proposed combination resulted in the design of a novel four-hole matched pixel detector (4-HMPD) configuration. Our novel 4-HMPD design based on large pixelated CZT detector was firstly compared to the standard one-hole matched pixel detector (1-HMPD) configuration using Monte Carlo simulation. We have also predicted the influence of pixel size, interpixel gap and source-to-collimator distance on the basis of resulting spatial resolution, sensitivity and crosstalk events fraction for three collimator hole lengths for Tc-99m (140 keV). Thereafter, we used the same detector and collimator settings of the 1-HMPD configuration as constructed with the D-SPECT camera module (Redlen Technologies, BC, Canada) for our 4-HMPD design to compare the performance of the two configurations. Our preliminary results showed that a large pixel size, a small interpixel gap and a small collimator hole length increased significantly the sensitivity at the detriment of spatial resolution. The performance comparison between the 4-HMPD and the 1-HMPD configurations demonstrated an improved reconstructed spatial resolution (by a factor two), higher contrast with the large sphere of the modified Jaszczak phantom (from 63.1% to 39.1%), clear appearance of cold spheres (> 14 mm diameter) and the cold cylinders (> 11.1 mm diameter). The crosstalk events fraction varied from 8.5% to 12.8%. Our novel detector/collimator combination allows less electronic readout complexity, less crosstalk events between pixels and twofold increase in septal thickness resulting in low septal penetration compared to the classical 1-HMPD configuration. It also showed the highest enhancement in terms of spatial resolution even in cases of low sensitivity with less injected activity, and outperformed the performance of existing conventional NaI (TI) crystal-based systems.

AB - Significant progress has been achieved in the design of pixelated CZT detectors dedicated to cardiac and breast SPECT imaging. However, their detector geometry and associated collimators' design have limited their clinical use. The aim of this work is to determine the best combination between a large pixelated CZT detector and parallel-hole collimator that can provide high spatial resolution at low injected activity with low-energy radiotracers. Our proposed combination resulted in the design of a novel four-hole matched pixel detector (4-HMPD) configuration. Our novel 4-HMPD design based on large pixelated CZT detector was firstly compared to the standard one-hole matched pixel detector (1-HMPD) configuration using Monte Carlo simulation. We have also predicted the influence of pixel size, interpixel gap and source-to-collimator distance on the basis of resulting spatial resolution, sensitivity and crosstalk events fraction for three collimator hole lengths for Tc-99m (140 keV). Thereafter, we used the same detector and collimator settings of the 1-HMPD configuration as constructed with the D-SPECT camera module (Redlen Technologies, BC, Canada) for our 4-HMPD design to compare the performance of the two configurations. Our preliminary results showed that a large pixel size, a small interpixel gap and a small collimator hole length increased significantly the sensitivity at the detriment of spatial resolution. The performance comparison between the 4-HMPD and the 1-HMPD configurations demonstrated an improved reconstructed spatial resolution (by a factor two), higher contrast with the large sphere of the modified Jaszczak phantom (from 63.1% to 39.1%), clear appearance of cold spheres (> 14 mm diameter) and the cold cylinders (> 11.1 mm diameter). The crosstalk events fraction varied from 8.5% to 12.8%. Our novel detector/collimator combination allows less electronic readout complexity, less crosstalk events between pixels and twofold increase in septal thickness resulting in low septal penetration compared to the classical 1-HMPD configuration. It also showed the highest enhancement in terms of spatial resolution even in cases of low sensitivity with less injected activity, and outperformed the performance of existing conventional NaI (TI) crystal-based systems.

KW - SPECT

KW - CZT detector

KW - parallel-hole collimator

KW - Monte Carlo

KW - crosstalk

KW - SPATIAL-RESOLUTION

KW - COMPENSATION

KW - PERFORMANCE

KW - CAMERAS

KW - SYSTEM

U2 - 10.1088/1748-0221/14/02/P02026

DO - 10.1088/1748-0221/14/02/P02026

M3 - Article

VL - 14

JO - Journal of Instrumentation

JF - Journal of Instrumentation

SN - 1748-0221

M1 - 02026

ER -

ID: 92178417