Publication

Compulsory treatment with clozapine: A retrospective long-term cohort study

Schulte, P. F. J., Stienen, J. J., Bogers, J., Cohen, D., van Dijk, D., Lionarons, W. H., Sanders, S. S. & Heck, A. H., 2007, In : International Journal of Law and Psychiatry. 30, 6, p. 539-545 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Schulte, P. F. J., Stienen, J. J., Bogers, J., Cohen, D., van Dijk, D., Lionarons, W. H., ... Heck, A. H. (2007). Compulsory treatment with clozapine: A retrospective long-term cohort study. International Journal of Law and Psychiatry, 30(6), 539-545. https://doi.org/10.1016/j.ijlp.2007.09.003

Author

Schulte, Peter F. J. ; Stienen, Juan J. ; Bogers, Jan ; Cohen, Dan ; van Dijk, Daniel ; Lionarons, Wendell H. ; Sanders, Sophia S. ; Heck, Adolph H. / Compulsory treatment with clozapine : A retrospective long-term cohort study. In: International Journal of Law and Psychiatry. 2007 ; Vol. 30, No. 6. pp. 539-545.

Harvard

Schulte, PFJ, Stienen, JJ, Bogers, J, Cohen, D, van Dijk, D, Lionarons, WH, Sanders, SS & Heck, AH 2007, 'Compulsory treatment with clozapine: A retrospective long-term cohort study' International Journal of Law and Psychiatry, vol. 30, no. 6, pp. 539-545. https://doi.org/10.1016/j.ijlp.2007.09.003

Standard

Compulsory treatment with clozapine : A retrospective long-term cohort study. / Schulte, Peter F. J.; Stienen, Juan J.; Bogers, Jan; Cohen, Dan; van Dijk, Daniel; Lionarons, Wendell H.; Sanders, Sophia S.; Heck, Adolph H.

In: International Journal of Law and Psychiatry, Vol. 30, No. 6, 2007, p. 539-545.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Schulte PFJ, Stienen JJ, Bogers J, Cohen D, van Dijk D, Lionarons WH et al. Compulsory treatment with clozapine: A retrospective long-term cohort study. International Journal of Law and Psychiatry. 2007;30(6):539-545. https://doi.org/10.1016/j.ijlp.2007.09.003


BibTeX

@article{30d4730df68f4e17a57c597d7d0554bc,
title = "Compulsory treatment with clozapine: A retrospective long-term cohort study",
abstract = "Background: Clozapine is the gold standard in treatment of treatment-resistant psychotic patients. We know little about the effects of compulsory treatment in patients unwilling to accept the necessary treatment.Aims: To assess the effectiveness, tolerability and safety of compulsory treatment with clozapine (CTC).Method: A cohort of 17 consecutive patients given compulsory treatment with clozapine were rated retrospectively by their treating psychiatrists on the basis of their case notes.Results: CGI-S decreased significantly over tithe until last observation after a mean of more than 15 months. No patient deteriorated as measured by CGI-1. At last observation as many as ten of the 11 patients still on clozapine were classified as much to very much improved. The degree of custodial restriction at last observation showed improvement in 11 patients and no change in six. No serious adverse events were observed.Conclusion: A trial of compulsory treatment with clozapine showed this treatment to be feasible, effective, safe and well tolerated. (c) 2007 Elsevier Inc. All rights reserved.",
keywords = "clozapine, schizophrenia, treatment refusal, treatment outcome, REFRACTORY SCHIZOPHRENIA, ATTITUDES, SYMPTOMS, TRIAL, DISORDER, SUICIDE, IMPACT, RISK, UK",
author = "Schulte, {Peter F. J.} and Stienen, {Juan J.} and Jan Bogers and Dan Cohen and {van Dijk}, Daniel and Lionarons, {Wendell H.} and Sanders, {Sophia S.} and Heck, {Adolph H.}",
year = "2007",
doi = "10.1016/j.ijlp.2007.09.003",
language = "English",
volume = "30",
pages = "539--545",
journal = "International Journal of Law and Psychiatry",
issn = "0160-2527",
publisher = "PERGAMON-ELSEVIER SCIENCE LTD",
number = "6",

}

RIS

TY - JOUR

T1 - Compulsory treatment with clozapine

T2 - A retrospective long-term cohort study

AU - Schulte, Peter F. J.

AU - Stienen, Juan J.

AU - Bogers, Jan

AU - Cohen, Dan

AU - van Dijk, Daniel

AU - Lionarons, Wendell H.

AU - Sanders, Sophia S.

AU - Heck, Adolph H.

PY - 2007

Y1 - 2007

N2 - Background: Clozapine is the gold standard in treatment of treatment-resistant psychotic patients. We know little about the effects of compulsory treatment in patients unwilling to accept the necessary treatment.Aims: To assess the effectiveness, tolerability and safety of compulsory treatment with clozapine (CTC).Method: A cohort of 17 consecutive patients given compulsory treatment with clozapine were rated retrospectively by their treating psychiatrists on the basis of their case notes.Results: CGI-S decreased significantly over tithe until last observation after a mean of more than 15 months. No patient deteriorated as measured by CGI-1. At last observation as many as ten of the 11 patients still on clozapine were classified as much to very much improved. The degree of custodial restriction at last observation showed improvement in 11 patients and no change in six. No serious adverse events were observed.Conclusion: A trial of compulsory treatment with clozapine showed this treatment to be feasible, effective, safe and well tolerated. (c) 2007 Elsevier Inc. All rights reserved.

AB - Background: Clozapine is the gold standard in treatment of treatment-resistant psychotic patients. We know little about the effects of compulsory treatment in patients unwilling to accept the necessary treatment.Aims: To assess the effectiveness, tolerability and safety of compulsory treatment with clozapine (CTC).Method: A cohort of 17 consecutive patients given compulsory treatment with clozapine were rated retrospectively by their treating psychiatrists on the basis of their case notes.Results: CGI-S decreased significantly over tithe until last observation after a mean of more than 15 months. No patient deteriorated as measured by CGI-1. At last observation as many as ten of the 11 patients still on clozapine were classified as much to very much improved. The degree of custodial restriction at last observation showed improvement in 11 patients and no change in six. No serious adverse events were observed.Conclusion: A trial of compulsory treatment with clozapine showed this treatment to be feasible, effective, safe and well tolerated. (c) 2007 Elsevier Inc. All rights reserved.

KW - clozapine

KW - schizophrenia

KW - treatment refusal

KW - treatment outcome

KW - REFRACTORY SCHIZOPHRENIA

KW - ATTITUDES

KW - SYMPTOMS

KW - TRIAL

KW - DISORDER

KW - SUICIDE

KW - IMPACT

KW - RISK

KW - UK

U2 - 10.1016/j.ijlp.2007.09.003

DO - 10.1016/j.ijlp.2007.09.003

M3 - Article

VL - 30

SP - 539

EP - 545

JO - International Journal of Law and Psychiatry

JF - International Journal of Law and Psychiatry

SN - 0160-2527

IS - 6

ER -

ID: 4655575