Publication

Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older

Beesems, S. G., Blom, M. T., van der Pas, M. H. A., Hulleman, M., van de Glind, E. M. M., van Munster, B. C., Tijssen, J. G. P., Tan, H. L., van Delden, J. J. M. & Koster, R. W., Sep-2015, In : Resuscitation. 94, p. 33-39 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Beesems, S. G., Blom, M. T., van der Pas, M. H. A., Hulleman, M., van de Glind, E. M. M., van Munster, B. C., Tijssen, J. G. P., Tan, H. L., van Delden, J. J. M., & Koster, R. W. (2015). Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older. Resuscitation, 94, 33-39. https://doi.org/10.1016/j.resuscitation.2015.06.017

Author

Beesems, Stefanie G. ; Blom, Marieke T. ; van der Pas, Martine H. A. ; Hulleman, Michiel ; van de Glind, Esther M. M. ; van Munster, Barbara C. ; Tijssen, Jan G. P. ; Tan, Hanno L. ; van Delden, Johannes J. M. ; Koster, Rudolph W. / Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older. In: Resuscitation. 2015 ; Vol. 94. pp. 33-39.

Harvard

Beesems, SG, Blom, MT, van der Pas, MHA, Hulleman, M, van de Glind, EMM, van Munster, BC, Tijssen, JGP, Tan, HL, van Delden, JJM & Koster, RW 2015, 'Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older', Resuscitation, vol. 94, pp. 33-39. https://doi.org/10.1016/j.resuscitation.2015.06.017

Standard

Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older. / Beesems, Stefanie G.; Blom, Marieke T.; van der Pas, Martine H. A.; Hulleman, Michiel; van de Glind, Esther M. M.; van Munster, Barbara C.; Tijssen, Jan G. P.; Tan, Hanno L.; van Delden, Johannes J. M.; Koster, Rudolph W.

In: Resuscitation, Vol. 94, 09.2015, p. 33-39.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Beesems SG, Blom MT, van der Pas MHA, Hulleman M, van de Glind EMM, van Munster BC et al. Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older. Resuscitation. 2015 Sep;94:33-39. https://doi.org/10.1016/j.resuscitation.2015.06.017


BibTeX

@article{4b30048008c84081bbc365d8f159c3ba,
title = "Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older",
abstract = "Introduction: Advanced age is reported to be associated with lower survival after out-of-hospital cardiac arrest (OHCA). We aimed to establish survival rate and neurological outcome at hospital discharge after OHCA in older patients and evaluated whether pre-OHCA comorbidity was associated with favorable neurologic outcome.Methods: From a prospective registry of all cardiopulmonary resuscitation (CPR) attempts after OHCA, we established survival in 1332 patients aged >= 70 years in whom resuscitation with non-traumatic etiology was attempted in 2009-2011. Pre-OHCA factors (age, gender, residing in long-term care institution, Charlson Comorbidity Index [CCI] score) and resuscitation parameters (initial rhythm, bystander witnessed, bystander CPR and time to defibrillator connection) with survival at hospital discharge with favorable neurologic outcome were regressed in the 851 patients of whom CCI was known.Results: We found a 12% survival to discharge rate in patients aged >= 70 years (70-79 years: 16%; >= 80 years: 8%, p = 0.001). Among surviving patients, 90% survived with favorable neurologic outcome. In a model with only pre-OHCA factors age was significantly associated with outcome (age OR 0.94, 95%CI 0.91-0.98), p = 0.003). High CCI score (>= 4) was not statistically significant when associated with survival (7% vs. 12%, OR 0.53, 95%CI (0.25-1.13), p = 0.10). When adjusted for resuscitation parameters, OR for high CCI was 0.71 (95% CI 0.28-1.80, p = 0.47), also none of the other pre-OHCA factors remained statistically significant.Conclusion: In the Netherlands, the survival rate in older patients was 12%; the great majority survived with favorable neurologic outcome. Resuscitation-related factors and not comorbidity determine outcome after OHCA in older patients. (C) 2015 Elsevier Ireland Ltd. All rights reserved.",
keywords = "Cardiopulmonary resuscitation, Survival, Aging, Advance care planning, Comorbidity, EUROPEAN-RESUSCITATION-COUNCIL, CARDIOCEREBRAL RESUSCITATION, COGNITIVE FUNCTION, IMPROVED SURVIVAL, LIFE, AGE, MANAGEMENT, IMPACT, RATES",
author = "Beesems, {Stefanie G.} and Blom, {Marieke T.} and {van der Pas}, {Martine H. A.} and Michiel Hulleman and {van de Glind}, {Esther M. M.} and {van Munster}, {Barbara C.} and Tijssen, {Jan G. P.} and Tan, {Hanno L.} and {van Delden}, {Johannes J. M.} and Koster, {Rudolph W.}",
year = "2015",
month = sep,
doi = "10.1016/j.resuscitation.2015.06.017",
language = "English",
volume = "94",
pages = "33--39",
journal = "Resuscitation",
issn = "0300-9572",
publisher = "ELSEVIER IRELAND LTD",

}

RIS

TY - JOUR

T1 - Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older

AU - Beesems, Stefanie G.

AU - Blom, Marieke T.

AU - van der Pas, Martine H. A.

AU - Hulleman, Michiel

AU - van de Glind, Esther M. M.

AU - van Munster, Barbara C.

AU - Tijssen, Jan G. P.

AU - Tan, Hanno L.

AU - van Delden, Johannes J. M.

AU - Koster, Rudolph W.

PY - 2015/9

Y1 - 2015/9

N2 - Introduction: Advanced age is reported to be associated with lower survival after out-of-hospital cardiac arrest (OHCA). We aimed to establish survival rate and neurological outcome at hospital discharge after OHCA in older patients and evaluated whether pre-OHCA comorbidity was associated with favorable neurologic outcome.Methods: From a prospective registry of all cardiopulmonary resuscitation (CPR) attempts after OHCA, we established survival in 1332 patients aged >= 70 years in whom resuscitation with non-traumatic etiology was attempted in 2009-2011. Pre-OHCA factors (age, gender, residing in long-term care institution, Charlson Comorbidity Index [CCI] score) and resuscitation parameters (initial rhythm, bystander witnessed, bystander CPR and time to defibrillator connection) with survival at hospital discharge with favorable neurologic outcome were regressed in the 851 patients of whom CCI was known.Results: We found a 12% survival to discharge rate in patients aged >= 70 years (70-79 years: 16%; >= 80 years: 8%, p = 0.001). Among surviving patients, 90% survived with favorable neurologic outcome. In a model with only pre-OHCA factors age was significantly associated with outcome (age OR 0.94, 95%CI 0.91-0.98), p = 0.003). High CCI score (>= 4) was not statistically significant when associated with survival (7% vs. 12%, OR 0.53, 95%CI (0.25-1.13), p = 0.10). When adjusted for resuscitation parameters, OR for high CCI was 0.71 (95% CI 0.28-1.80, p = 0.47), also none of the other pre-OHCA factors remained statistically significant.Conclusion: In the Netherlands, the survival rate in older patients was 12%; the great majority survived with favorable neurologic outcome. Resuscitation-related factors and not comorbidity determine outcome after OHCA in older patients. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

AB - Introduction: Advanced age is reported to be associated with lower survival after out-of-hospital cardiac arrest (OHCA). We aimed to establish survival rate and neurological outcome at hospital discharge after OHCA in older patients and evaluated whether pre-OHCA comorbidity was associated with favorable neurologic outcome.Methods: From a prospective registry of all cardiopulmonary resuscitation (CPR) attempts after OHCA, we established survival in 1332 patients aged >= 70 years in whom resuscitation with non-traumatic etiology was attempted in 2009-2011. Pre-OHCA factors (age, gender, residing in long-term care institution, Charlson Comorbidity Index [CCI] score) and resuscitation parameters (initial rhythm, bystander witnessed, bystander CPR and time to defibrillator connection) with survival at hospital discharge with favorable neurologic outcome were regressed in the 851 patients of whom CCI was known.Results: We found a 12% survival to discharge rate in patients aged >= 70 years (70-79 years: 16%; >= 80 years: 8%, p = 0.001). Among surviving patients, 90% survived with favorable neurologic outcome. In a model with only pre-OHCA factors age was significantly associated with outcome (age OR 0.94, 95%CI 0.91-0.98), p = 0.003). High CCI score (>= 4) was not statistically significant when associated with survival (7% vs. 12%, OR 0.53, 95%CI (0.25-1.13), p = 0.10). When adjusted for resuscitation parameters, OR for high CCI was 0.71 (95% CI 0.28-1.80, p = 0.47), also none of the other pre-OHCA factors remained statistically significant.Conclusion: In the Netherlands, the survival rate in older patients was 12%; the great majority survived with favorable neurologic outcome. Resuscitation-related factors and not comorbidity determine outcome after OHCA in older patients. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

KW - Cardiopulmonary resuscitation

KW - Survival

KW - Aging

KW - Advance care planning

KW - Comorbidity

KW - EUROPEAN-RESUSCITATION-COUNCIL

KW - CARDIOCEREBRAL RESUSCITATION

KW - COGNITIVE FUNCTION

KW - IMPROVED SURVIVAL

KW - LIFE

KW - AGE

KW - MANAGEMENT

KW - IMPACT

KW - RATES

U2 - 10.1016/j.resuscitation.2015.06.017

DO - 10.1016/j.resuscitation.2015.06.017

M3 - Article

VL - 94

SP - 33

EP - 39

JO - Resuscitation

JF - Resuscitation

SN - 0300-9572

ER -

ID: 79051886