Publication

Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands in 1996 and in 2007: Differential changes by gender and age

van Aar, F., de Moraes, M., Morre, S. A., van Bergen, J. E. A. M., van der Klis, F. R. M., Land, J. A., van der Sande, M. A. B. & van den Broek, I. V. F., Aug-2014, In : Sexually Transmitted Infections. 90, 5, p. 434-440 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

van Aar, F., de Moraes, M., Morre, S. A., van Bergen, J. E. A. M., van der Klis, F. R. M., Land, J. A., ... van den Broek, I. V. F. (2014). Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands in 1996 and in 2007: Differential changes by gender and age. Sexually Transmitted Infections, 90(5), 434-440. https://doi.org/10.1136/sextrans-2013-051074

Author

van Aar, F. ; de Moraes, M. ; Morre, S. A. ; van Bergen, J. E. A. M. ; van der Klis, F. R. M. ; Land, J. A. ; van der Sande, M. A. B. ; van den Broek, I. V. F. / Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands in 1996 and in 2007 : Differential changes by gender and age. In: Sexually Transmitted Infections. 2014 ; Vol. 90, No. 5. pp. 434-440.

Harvard

van Aar, F, de Moraes, M, Morre, SA, van Bergen, JEAM, van der Klis, FRM, Land, JA, van der Sande, MAB & van den Broek, IVF 2014, 'Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands in 1996 and in 2007: Differential changes by gender and age', Sexually Transmitted Infections, vol. 90, no. 5, pp. 434-440. https://doi.org/10.1136/sextrans-2013-051074

Standard

Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands in 1996 and in 2007 : Differential changes by gender and age. / van Aar, F.; de Moraes, M.; Morre, S. A.; van Bergen, J. E. A. M.; van der Klis, F. R. M.; Land, J. A.; van der Sande, M. A. B.; van den Broek, I. V. F.

In: Sexually Transmitted Infections, Vol. 90, No. 5, 08.2014, p. 434-440.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

van Aar F, de Moraes M, Morre SA, van Bergen JEAM, van der Klis FRM, Land JA et al. Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands in 1996 and in 2007: Differential changes by gender and age. Sexually Transmitted Infections. 2014 Aug;90(5):434-440. https://doi.org/10.1136/sextrans-2013-051074


BibTeX

@article{df431af8c9d74e378ce4e0c945207b92,
title = "Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands in 1996 and in 2007: Differential changes by gender and age",
abstract = "Objectives Chlamydia trachomatis (CT) reporting rates from sexually transmitted infection clinics and general practitioners have shown a rising trend in the Netherlands. It is unknown to what extent this reflects increased CT transmission or improved case finding. To achieve more insight into the CT epidemic, we explored the CT IgG seroprevalence (a marker of past CT infection) in the general population of the Netherlands in 1996 and in 2007.Methods From two population-based studies in 1996 and 2007, serum samples, demographic and sexual behaviour outcomes were examined, including 1246 men and 1930 women aged 15-39 years. Serum CT IgG antibodies were analysed using the Medac CT IgG ELISA test. Multivariate logistic regression analyses explored the seroprevalence and determinants over time.Results The CT IgG seroprevalence was higher in women than in men (10{\%} vs 6{\%}). Among women aged 25-39 years the seroprevalence was lower in 2007 (9{\%}) than in 1996 (14{\%}; adjusted OR (aOR) 0.6, 95{\%} CI 0.4 to 0.8). There was no statistical evidence of a difference in seroprevalence within birth cohorts. Factors associated with seropositivity were male gender (aOR 0.4, 95{\%} CI 0.3 to 0.7), a self-reported history of CT infection (aOR 5.1, 95{\%} CI 2.6 to 10.0), age 25-39 years (aOR 1.7, 95{\%} CI 1.1 to 2.7), non-Western ethnicity (aOR 2.2, 95{\%} CI 1.4 to 3.3) and >= recent sexual partners (aOR 2.2, 95{\%} CI 1.3 to 3.5).Conclusions Between 1996 and 2007 the proportion of individuals in the general population with CT IgG antibodies was lower among women aged 25-39 years, but remained similar among younger women and men.",
keywords = "ACUTE SALPINGITIS, INFECTION, SEROLOGY, WOMEN, INFERTILITY, PREVALENCE, ANTIBODIES, ASSAY",
author = "{van Aar}, F. and {de Moraes}, M. and Morre, {S. A.} and {van Bergen}, {J. E. A. M.} and {van der Klis}, {F. R. M.} and Land, {J. A.} and {van der Sande}, {M. A. B.} and {van den Broek}, {I. V. F.}",
year = "2014",
month = "8",
doi = "10.1136/sextrans-2013-051074",
language = "English",
volume = "90",
pages = "434--440",
journal = "Sexually Transmitted Infections",
issn = "1368-4973",
publisher = "BMJ PUBLISHING GROUP",
number = "5",

}

RIS

TY - JOUR

T1 - Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands in 1996 and in 2007

T2 - Differential changes by gender and age

AU - van Aar, F.

AU - de Moraes, M.

AU - Morre, S. A.

AU - van Bergen, J. E. A. M.

AU - van der Klis, F. R. M.

AU - Land, J. A.

AU - van der Sande, M. A. B.

AU - van den Broek, I. V. F.

PY - 2014/8

Y1 - 2014/8

N2 - Objectives Chlamydia trachomatis (CT) reporting rates from sexually transmitted infection clinics and general practitioners have shown a rising trend in the Netherlands. It is unknown to what extent this reflects increased CT transmission or improved case finding. To achieve more insight into the CT epidemic, we explored the CT IgG seroprevalence (a marker of past CT infection) in the general population of the Netherlands in 1996 and in 2007.Methods From two population-based studies in 1996 and 2007, serum samples, demographic and sexual behaviour outcomes were examined, including 1246 men and 1930 women aged 15-39 years. Serum CT IgG antibodies were analysed using the Medac CT IgG ELISA test. Multivariate logistic regression analyses explored the seroprevalence and determinants over time.Results The CT IgG seroprevalence was higher in women than in men (10% vs 6%). Among women aged 25-39 years the seroprevalence was lower in 2007 (9%) than in 1996 (14%; adjusted OR (aOR) 0.6, 95% CI 0.4 to 0.8). There was no statistical evidence of a difference in seroprevalence within birth cohorts. Factors associated with seropositivity were male gender (aOR 0.4, 95% CI 0.3 to 0.7), a self-reported history of CT infection (aOR 5.1, 95% CI 2.6 to 10.0), age 25-39 years (aOR 1.7, 95% CI 1.1 to 2.7), non-Western ethnicity (aOR 2.2, 95% CI 1.4 to 3.3) and >= recent sexual partners (aOR 2.2, 95% CI 1.3 to 3.5).Conclusions Between 1996 and 2007 the proportion of individuals in the general population with CT IgG antibodies was lower among women aged 25-39 years, but remained similar among younger women and men.

AB - Objectives Chlamydia trachomatis (CT) reporting rates from sexually transmitted infection clinics and general practitioners have shown a rising trend in the Netherlands. It is unknown to what extent this reflects increased CT transmission or improved case finding. To achieve more insight into the CT epidemic, we explored the CT IgG seroprevalence (a marker of past CT infection) in the general population of the Netherlands in 1996 and in 2007.Methods From two population-based studies in 1996 and 2007, serum samples, demographic and sexual behaviour outcomes were examined, including 1246 men and 1930 women aged 15-39 years. Serum CT IgG antibodies were analysed using the Medac CT IgG ELISA test. Multivariate logistic regression analyses explored the seroprevalence and determinants over time.Results The CT IgG seroprevalence was higher in women than in men (10% vs 6%). Among women aged 25-39 years the seroprevalence was lower in 2007 (9%) than in 1996 (14%; adjusted OR (aOR) 0.6, 95% CI 0.4 to 0.8). There was no statistical evidence of a difference in seroprevalence within birth cohorts. Factors associated with seropositivity were male gender (aOR 0.4, 95% CI 0.3 to 0.7), a self-reported history of CT infection (aOR 5.1, 95% CI 2.6 to 10.0), age 25-39 years (aOR 1.7, 95% CI 1.1 to 2.7), non-Western ethnicity (aOR 2.2, 95% CI 1.4 to 3.3) and >= recent sexual partners (aOR 2.2, 95% CI 1.3 to 3.5).Conclusions Between 1996 and 2007 the proportion of individuals in the general population with CT IgG antibodies was lower among women aged 25-39 years, but remained similar among younger women and men.

KW - ACUTE SALPINGITIS

KW - INFECTION

KW - SEROLOGY

KW - WOMEN

KW - INFERTILITY

KW - PREVALENCE

KW - ANTIBODIES

KW - ASSAY

U2 - 10.1136/sextrans-2013-051074

DO - 10.1136/sextrans-2013-051074

M3 - Article

VL - 90

SP - 434

EP - 440

JO - Sexually Transmitted Infections

JF - Sexually Transmitted Infections

SN - 1368-4973

IS - 5

ER -

ID: 13703724