Publication

Chemokines and their receptors in central nervous system disease

Biber, K., de Jong, EK., van Weering, HRJ. & Boddeke, HWGM., Jan-2006, In : CURRENT DRUG TARGETS. 7, 1, p. 29-46 18 p.

Research output: Contribution to journalReview articleAcademicpeer-review

APA

Biber, K., de Jong, EK., van Weering, HRJ., & Boddeke, HWGM. (2006). Chemokines and their receptors in central nervous system disease. CURRENT DRUG TARGETS, 7(1), 29-46.

Author

Biber, K ; de Jong, EK ; van Weering, HRJ ; Boddeke, HWGM. / Chemokines and their receptors in central nervous system disease. In: CURRENT DRUG TARGETS. 2006 ; Vol. 7, No. 1. pp. 29-46.

Harvard

Biber, K, de Jong, EK, van Weering, HRJ & Boddeke, HWGM 2006, 'Chemokines and their receptors in central nervous system disease', CURRENT DRUG TARGETS, vol. 7, no. 1, pp. 29-46.

Standard

Chemokines and their receptors in central nervous system disease. / Biber, K; de Jong, EK; van Weering, HRJ; Boddeke, HWGM.

In: CURRENT DRUG TARGETS, Vol. 7, No. 1, 01.2006, p. 29-46.

Research output: Contribution to journalReview articleAcademicpeer-review

Vancouver

Biber K, de Jong EK, van Weering HRJ, Boddeke HWGM. Chemokines and their receptors in central nervous system disease. CURRENT DRUG TARGETS. 2006 Jan;7(1):29-46.


BibTeX

@article{a668427e13ee4700ad6a227e9c912dc2,
title = "Chemokines and their receptors in central nervous system disease",
abstract = "Almost a decade ago, it was discovered that the human deficiency virus (HIV) makes use of chemokine receptors to infect blood cells. This appreciation of the clinical relevance of specific chemokine receptors has initiated a considerable boost in the field of chemokine research. It is clear today that chemokine signaling orchestrates the immune system and is widely involved in both physiological and pathophysiological processes. Since the chemokine system offers various targets through which pathology could be influenced, most pharmaceutical companies have chosen this system as a therapeutic target for a variety of diseases. Here recent developments concerning the role of chemokines in diseases of the central nervous system (CNS) as well as their possible therapeutic relevance are discussed.",
keywords = "EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS, MONOCYTE CHEMOATTRACTANT PROTEIN-1, FOCAL CEREBRAL-ISCHEMIA, EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS, BLOOD-BRAIN-BARRIER, MACROPHAGE INFLAMMATORY PROTEIN-1, MULTIPLE-SCLEROSIS LESIONS, INDUCED NEUTROPHIL CHEMOATTRACTANT, INTERFERON-INDUCIBLE PROTEIN-10, CULTURED HUMAN ASTROCYTES",
author = "K Biber and {de Jong}, EK and {van Weering}, HRJ and HWGM Boddeke",
year = "2006",
month = jan,
language = "English",
volume = "7",
pages = "29--46",
journal = "CURRENT DRUG TARGETS",
issn = "1389-4501",
number = "1",

}

RIS

TY - JOUR

T1 - Chemokines and their receptors in central nervous system disease

AU - Biber, K

AU - de Jong, EK

AU - van Weering, HRJ

AU - Boddeke, HWGM

PY - 2006/1

Y1 - 2006/1

N2 - Almost a decade ago, it was discovered that the human deficiency virus (HIV) makes use of chemokine receptors to infect blood cells. This appreciation of the clinical relevance of specific chemokine receptors has initiated a considerable boost in the field of chemokine research. It is clear today that chemokine signaling orchestrates the immune system and is widely involved in both physiological and pathophysiological processes. Since the chemokine system offers various targets through which pathology could be influenced, most pharmaceutical companies have chosen this system as a therapeutic target for a variety of diseases. Here recent developments concerning the role of chemokines in diseases of the central nervous system (CNS) as well as their possible therapeutic relevance are discussed.

AB - Almost a decade ago, it was discovered that the human deficiency virus (HIV) makes use of chemokine receptors to infect blood cells. This appreciation of the clinical relevance of specific chemokine receptors has initiated a considerable boost in the field of chemokine research. It is clear today that chemokine signaling orchestrates the immune system and is widely involved in both physiological and pathophysiological processes. Since the chemokine system offers various targets through which pathology could be influenced, most pharmaceutical companies have chosen this system as a therapeutic target for a variety of diseases. Here recent developments concerning the role of chemokines in diseases of the central nervous system (CNS) as well as their possible therapeutic relevance are discussed.

KW - EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS

KW - MONOCYTE CHEMOATTRACTANT PROTEIN-1

KW - FOCAL CEREBRAL-ISCHEMIA

KW - EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

KW - BLOOD-BRAIN-BARRIER

KW - MACROPHAGE INFLAMMATORY PROTEIN-1

KW - MULTIPLE-SCLEROSIS LESIONS

KW - INDUCED NEUTROPHIL CHEMOATTRACTANT

KW - INTERFERON-INDUCIBLE PROTEIN-10

KW - CULTURED HUMAN ASTROCYTES

M3 - Review article

VL - 7

SP - 29

EP - 46

JO - CURRENT DRUG TARGETS

JF - CURRENT DRUG TARGETS

SN - 1389-4501

IS - 1

ER -

ID: 4392378