Cerebral Autoregulation in Sick Infants: Current InsightsKooi, E. M. W. & Richter, A. E., Sep-2020, In : Clinics in perinatology. 47, 3, p. 449-467 19 p.
Research output: Contribution to journal › Review article › Academic › peer-review
Cerebrovascular autoregulation is the ability to maintain stable cerebral blood flow within a range of cerebral perfusion pressures. When cerebral perfusion pressure is outside the limits of effective autoregulation, the brain is subjected to hypoperfusion or hyperperfusion, which may cause vascular injury, hemorrhage, and/or hypoxic white matter injury. Infants born preterm, after fetal growth restriction, with congenital heart disease, or with hypoxic-ischemic encephalopathy are susceptible to a failure of cerebral autoregulation. Bedside assessment of cerebrovascular autoregulation would offer the opportunity to prevent brain injury. Clinicians need to know which patient populations and circumstances are associated with impaired/absent cerebral autoregulation.
|Number of pages||19|
|Journal||Clinics in perinatology|
|Publication status||Published - Sep-2020|
- Cerebral autoregulation, Cerebral hemodynamics, Preterm infant, Fetal growth restriction, Hypoxic-ischemic encephalopathy, Congenital heart disease, Neonatal surgery, NEAR-INFRARED SPECTROSCOPY, HYPOXIC-ISCHEMIC ENCEPHALOPATHY, TISSUE OXYGEN EXTRACTION, PRETERM INFANTS, BLOOD-FLOW, CEREBROVASCULAR AUTOREGULATION, MAGNESIUM-SULFATE, PREMATURE-INFANTS, NECROTIZING ENTEROCOLITIS, PRESSURE AUTOREGULATION