Cell-laden alginate hydrogels for the treatment of diabetes

Izeia, L., Eufrasio-da-Silva, T., Dolatshahi-Pirouz, A., Ostrovidov, S., Paolone, G., Peppas, N. A., De Vos, P., Emerich, D. & Orive, G., 9-Jun-2020, In : Expert Opinion on Drug Delivery. 17, 8, p. 1113-1118 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Copy link to clipboard


  • Cell-laden alginate hydrogels for the treatment of diabetes

    Final author's version, 1.18 MB, PDF document

    Embargo ends: 09/06/2021

    Request copy

  • Cell-laden alginate hydrogels for the treatment of diabetes

    Final publisher's version, 2.21 MB, PDF document

    Request copy


  • Lukin Izeia
  • Tatiane Eufrasio-da-Silva
  • Alireza Dolatshahi-Pirouz
  • Serge Ostrovidov
  • Giovanna Paolone
  • Nicholas A Peppas
  • Paul De Vos
  • Dwaine Emerich
  • Gorka Orive

INTRODUCTION: Diabetes mellitus is an ever-increasing medical condition that currently suffers 1 of 11 adults who may have lifelong commitment with insulin injections. Cell-laden hydrogels releasing insulin may provide the ultimate means of correcting diabetes. Here, we provide insights of this cell-based approach including latest preclinical and clinical progress both from academia and industry.

AREA COVERED: The present article focuses on reviewing latest advances in cell-laden hydrogels both from the technological and biological perspective. The most relevant clinical results including clinical trials are also discussed.

EXPERT OPINION: Current progress in technological issues (stem cells, devices, biomaterials) have contributed cell encapsulation science to have an very relevant progress in the field of diabetes treatment.

Original languageEnglish
Pages (from-to)1113-1118
Number of pages7
JournalExpert Opinion on Drug Delivery
Issue number8
Publication statusE-pub ahead of print - 9-Jun-2020

ID: 127479755