Publication

Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin

Demaria, M., Desprez, P. Y., Campisi, J. & Velarde, M. C., Jul-2015, In : Journal of Investigative Dermatology. 135, 7, p. 1722-6 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Demaria, M., Desprez, P. Y., Campisi, J., & Velarde, M. C. (2015). Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin. Journal of Investigative Dermatology, 135(7), 1722-6. https://doi.org/10.1038/jid.2015.108

Author

Demaria, Marco ; Desprez, Pierre Yves ; Campisi, Judith ; Velarde, Michael C. / Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin. In: Journal of Investigative Dermatology. 2015 ; Vol. 135, No. 7. pp. 1722-6.

Harvard

Demaria, M, Desprez, PY, Campisi, J & Velarde, MC 2015, 'Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin' Journal of Investigative Dermatology, vol. 135, no. 7, pp. 1722-6. https://doi.org/10.1038/jid.2015.108

Standard

Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin. / Demaria, Marco; Desprez, Pierre Yves; Campisi, Judith; Velarde, Michael C.

In: Journal of Investigative Dermatology, Vol. 135, No. 7, 07.2015, p. 1722-6.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Demaria M, Desprez PY, Campisi J, Velarde MC. Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin. Journal of Investigative Dermatology. 2015 Jul;135(7):1722-6. https://doi.org/10.1038/jid.2015.108


BibTeX

@article{3ecb10829c7842a3abbbc3ac18264cc0,
title = "Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin",
abstract = "Human and mouse skin accumulate senescent cells in both the epidermis and dermis during aging. When chronically present, senescent cells are thought to enhance the age-dependent deterioration of the skin during extrinsic and intrinsic aging. However, when transiently present, senescent cells promote optimal wound healing. Here, we review recent studies on how senescent cells and the senescence-associated secretory phenotype contribute to different physiological and pathophysiological conditions in the skin with a focus on some of the cell autonomous and non-autonomous functions of senescent cells in the context of skin aging and wound healing.",
keywords = "Animals, Cell Aging, Cell Differentiation, Cell Division, Epidermis, Female, Fibroblasts, Homeostasis, Humans, Male, Mice, Sensitivity and Specificity, Skin, Skin Aging, Wound Healing",
author = "Marco Demaria and Desprez, {Pierre Yves} and Judith Campisi and Velarde, {Michael C}",
year = "2015",
month = "7",
doi = "10.1038/jid.2015.108",
language = "English",
volume = "135",
pages = "1722--6",
journal = "Journal of Investigative Dermatology",
issn = "0022-202X",
publisher = "ELSEVIER SCIENCE INC",
number = "7",

}

RIS

TY - JOUR

T1 - Cell Autonomous and Non-Autonomous Effects of Senescent Cells in the Skin

AU - Demaria, Marco

AU - Desprez, Pierre Yves

AU - Campisi, Judith

AU - Velarde, Michael C

PY - 2015/7

Y1 - 2015/7

N2 - Human and mouse skin accumulate senescent cells in both the epidermis and dermis during aging. When chronically present, senescent cells are thought to enhance the age-dependent deterioration of the skin during extrinsic and intrinsic aging. However, when transiently present, senescent cells promote optimal wound healing. Here, we review recent studies on how senescent cells and the senescence-associated secretory phenotype contribute to different physiological and pathophysiological conditions in the skin with a focus on some of the cell autonomous and non-autonomous functions of senescent cells in the context of skin aging and wound healing.

AB - Human and mouse skin accumulate senescent cells in both the epidermis and dermis during aging. When chronically present, senescent cells are thought to enhance the age-dependent deterioration of the skin during extrinsic and intrinsic aging. However, when transiently present, senescent cells promote optimal wound healing. Here, we review recent studies on how senescent cells and the senescence-associated secretory phenotype contribute to different physiological and pathophysiological conditions in the skin with a focus on some of the cell autonomous and non-autonomous functions of senescent cells in the context of skin aging and wound healing.

KW - Animals

KW - Cell Aging

KW - Cell Differentiation

KW - Cell Division

KW - Epidermis

KW - Female

KW - Fibroblasts

KW - Homeostasis

KW - Humans

KW - Male

KW - Mice

KW - Sensitivity and Specificity

KW - Skin

KW - Skin Aging

KW - Wound Healing

U2 - 10.1038/jid.2015.108

DO - 10.1038/jid.2015.108

M3 - Article

VL - 135

SP - 1722

EP - 1726

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

SN - 0022-202X

IS - 7

ER -

ID: 26937544