Publication

Bioconjugation of metal-based compounds for targeted biomedical applications: from drug delivery to mass spectrometry imaging

Han, J., 2020, [Groningen]: University of Groningen. 135 p.

Research output: ThesisThesis fully internal (DIV)

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Documents

  • Title and contents

    Final publisher's version, 217 KB, PDF document

  • Chapter 1

    Final publisher's version, 2.27 MB, PDF document

  • Chapter 2

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  • Chapter 3

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  • Chapter 4

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  • Chapter 5

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  • Chapter 6

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  • Summary

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  • Samenvatting

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  • Acknowledgments

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  • Complete thesis

    Final publisher's version, 9.15 MB, PDF document

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  • Propositions

    Final publisher's version, 85.9 KB, PDF document

DOI

This thesis described the synthesis, carachterization, and application of bioconjugated metal-based compounds. The bioconjugated Pd-based metallocages are non-toxic to healthy tissue cells. Their well defined structure make them ideal tools for targeted delivery of anticancer drug cisplatin. The bioconjugated Ru-based compounds exhibit high photocleavable property which can be used as mass-tag for the targted mass spectrometry imaging of tumor tissue.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
Supervisors/Advisors
Award date7-Feb-2020
Place of Publication[Groningen]
Publisher
Print ISBNs978-94-034-2437-8
Electronic ISBNs978-94-034-2436-1
Publication statusPublished - 2020

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