Publication

Awareness among European healthcare professionals of four recent drug safety issues

de Vries, S., 3-Oct-2017, (Unpublished).

Research output: Contribution to conferencePosterAcademic

Awareness among European healthcare professionals of four recent drug safety issues

PhD Sieta T. de Vries1, PhD Petra Denig1, PhD Peter G.M. Mol1,2
1Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, The Netherlands
2Dutch Medicines Evaluation Board, The Netherlands

Background
Knowledge of healthcare professionals’ (HCPs) awareness of specific drug safety issues and factors that are associated with awareness can help to improve safety communication strategies. This study aimed to assess European HCPs’ awareness of specific safety issues, sources through which HCPs had become aware, and which HCP characteristics are associated with awareness.

Methods
In the context of the Strengthening Collaboration for Operating Pharmacovigilance in Europe (SCOPE) Joint Action, a web-based survey was distributed among HCPs from nine European countries (i.e. Denmark, Spain, Croatia, Ireland, Italy, the Netherlands, Norway, Sweden, and the UK). HCPs were asked about awareness of the recent safety issues of combined hormonal contraceptives, diclofenac, valproate, and ivabradine. HCPs aware of a specific safety issue were additionally asked to indicate the source through which they had become aware. Associations between HCP characteristics (gender, profession, years of accreditation) and awareness of each of the safety issues were assessed using a penalized maximum likelihood logistic regression analysis per country.

Results
In total, 3,620 HCPs were included ranging from 68 from Denmark to 1,075 from Spain. Awareness was highest for the diclofenac safety issue (91%). Variation across the countries was largest for the ivabradine safety issue
(range 24% in Sweden to 87% in Italy). Direct Healthcare Professional Communications were the main source of awareness followed by information on a website or in a newsletter but this differed across the countries. Of the
assessed HCP characteristics, profession was mostly associated with awareness. Cardiologists were less aware than general practitioners, except for the ivabradine issue where cardiologists in the Netherlands were more aware than general practitioners (OR 8.79; 95% CI 2.64-29.22).

Conclusion
In several countries, additional strategies are needed to improve awareness of safety issues. DHPCs may not be sufficient to reach cardiologists when communicating safety issues of drugs outside their field.
Original languageEnglish
Publication statusUnpublished - 3-Oct-2017
EventFIGON Dutch Medicines Days - Ede, Netherlands
Duration: 2-Oct-20173-Oct-2017

Conference

ConferenceFIGON Dutch Medicines Days
CountryNetherlands
CityEde
Period02/10/201703/10/2017

Event

FIGON Dutch Medicines Days

02/10/201703/10/2017

Ede, Netherlands

Event: Conference

Related Prizes
  1. Poster prize

    Sieta de Vries (Recipient), 3-Oct-2017

    PrizeAcademic

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