Autophagy in normal hematopoiesis and leukemia: Biological and therapeutic implicationsFolkerts, H., 2019, [Groningen]: Rijksuniversiteit Groningen. 220 p.
Research output: Thesis › Thesis fully internal (DIV) › Academic
All together the studies in this thesis show that autophagy is an essential survival mechanism for both normal hematopoietic and AML cells and MDS erythroblasts. Altered expression of autophagy-associated genes might have consequences for drug resistance. Therefore, these findings suggest that inhibition of autophagy might be a promising therapeutic strategy for the treatment of AML.
|Qualification||Doctor of Philosophy|
|Place of Publication||[Groningen]|
|Publication status||Published - 2019|
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